Southern California's
Startup Directory
Series B$84.3MRebuilding healthcare with AI at the core
Pre-Seed$250KBetter, faster tech vendor research
Series D$833.1MWe provide efficient in-space mobility that moves payloads from low Earth orbit to any destination. Our vehicles deliver rapid, reliable access, reducing costs and timelines to make space operations feasible for commercial, government, and scientific missions.
Series C$80.1MOutpace AI-driven attacks. Unify Digital Risk Protection, Human Risk Management, and Email Security to stop digital threats before they scale, empower your teams to lead your defense, and scale your SOC with agentic AI.
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
Seed$8.1MOrbital defense built for scale.
Series A$8.0MOUTERSPACES INC. PHILADELPHIAS PREMIER DESIGNER AND BUILDER OF LANDSCAPE ARCHITECTURAL ELEMENTS, SWIMMING POOLS, FOUNTAINS, AND OUTDOOR LIVING SPACES.
Seed$7.9MCelestial Therapeutics is developing novel therapies based on innovative and groundbreaking science to treat, prevent and cure infectious diseases, rare diseases and cancers.
Series A$7.7MWe build kitchen intelligence tools to cut food waste, eliminate single-use packaging and optimize resources across every stage of food production.
$7.6MEliseAI is the industry-leading AI platform transforming both property management and healthcare through automation and conversational AI that help housing and healthcare organizations streamline communications and improve operational efficiency.
Series A$7.6MThe infrastructure for the distribution of liquid hydrogen.
Seed$7.6MEzra Climate was founded by Dan Rosen and Dori Rutkevitz, who previously helped scale Mosaic, a solar fintech platform that financed over $15B in projects; Ezra raised an $8M seed round for AI infrastructure serving private capital markets.
Series A$7.5MEpiPlex™ assay detects RNA modifications by proximity barcoding and short read RNA sequencing, revealing insights into gene regulation for disease research.