San Diego

Shield AI is a defense-tech company building the world's best AI pilots and next-generation aircraft.

Developing the next generation of oncology therapies for patients.

We're dedicated to defeating cancer with therapies that target disease, not immune systems. Find our investigational immunotherapy and cell therapy products.

Novartis completed its acquisition of Avidity Biosciences in 2026, folding the San Diego RNA-therapeutics company into its late-stage neuroscience pipeline.

Crinetics is here for endocrine disease patients who are eager to find therapies that provide effective disease control and more simplicity in their lives.

Iambic has created a cutting-edge AI-driven platform to tackle the most challenging design problems in drug discovery and address unmet patient need.

Merck agreed to acquire the San Diego biotech for approximately $9.2 billion in November 2025.

Founded in 2012 by two UC San Diego PhD alumni, Jared Tangney and Josh Windmiller, originally under the name Electrozyme.

Co-founded by Drew Weissman, the 2023 Nobel Prize winner in Physiology or Medicine for mRNA vaccine research, alongside CAR-T pioneer Carl June; the company was later acquired by AbbVie.

Science Seralutinib Seralutinib is an inhaled PDGFRα/β, CSF1R, and c‑KIT inhibitor designed to be delivered via dry powder inhaler for the potential treatment of pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease (PH-ILD).

Founded by Ken Song and launched with over $370 million (later exceeding $500 million) from investors including Venrock Healthcare Capital Partners, RA Capital Management, and Fairmount.

Has raised over $350 million from major healthcare investors including OrbiMed, BlackRock, and Bain Capital Life Sciences.

ABA therapy and comprehensive autism care for children, from diagnosis through developmental and medical therapy. Physician-led and in-network. Find a center near you.

We are on a mission to exponentially improve the number of quality years for patients.

We are a biopharmaceutical company focused on the development of proprietary cannabinoid derivatives for the treatment of glaucoma and other diseases with significant unmet medical needs. Our innovative approach to drug development combines strong science with the drive to find solutions where the need is the greatest.

Our mission is to realize the promise of precision medicines to help patients with cancer lead better, longer lives.

Endeavor BioMedicines is a clinical-stage biotechnology company developing transformational medicines for life-threatening diseases.

A Foresite Labs-incubated biotech backed by Foresite Capital, Qiming Venture Partners, and Samsara BioCapital that raised over $100M before being folded into Candid Therapeutics' $370M launch in 2024.

Autobahn aims to improve life health for people affected by CNS disorders by driving the regenerative power of the human body.

We at Boundless Bio are pioneers in understanding and treating the most intractable cancers. We have charted a new spatial map of the cancer genome within cancer cells and are harnessing our scientific founders’ discoveries about “extrachromosomal DNA,” or ecDNA, to drive a revolution in cancer therapeutics.

TRC 2004 was co-founded by Third Rock Ventures and Two River, the same investor group behind Kite Pharma (sold to Gilead for roughly $11.9B), and later emerged publicly as Candid Therapeutics with a $370M capital raise.

Aardvark Therapeutics is a clinical-stage biopharmaceutical company developing novel, small-molecule therapies designed to inhibit hunger and treat metabolic

Firestorm Labs - Democratize the fight with radically-affordable, mission-adaptable power for air, land, and sea.

Discover how Bionano is striving to elevate health and wellness for all through optical genome mapping (OGM) solutions that transform the way the world sees the genome.

We’re an integrated photonics company in California building the light engines that power the next era of quantum technology — from advanced computing to precision sensing.

Gene therapy company that emerged from stealth in June 2023 with a $51M Series A co-led by Westlake Village BioPartners, developing AAV-based genetic medicines for muscle and heart disease.

San Diego biologics company led by CEO Krisztina Zsebo, PhD, developing vascular biologic therapies for ischemic stroke and acute cardiovascular disease.

Plexium is a next-generation targeted protein degradation (TPD) company that discovers Monovalent Direct Degraders and Molecular Glues.

Electrochemical Additive Manufacturing Mass Production of Next Generation Components High-Resolution Metal 3D Printing at Scale Electrochemical Additive Manufacturing (ECAM) is... Read More

Strata Millenia is tied to Strata Equity Group, which partnered with Ryan Companies to develop a 278-unit multifamily community within the Millenia master-planned district in Chula Vista.

SRT Therapeutics was founded in 2024 by former leaders of Prometheus Biosciences, including President & CEO Lauren Otsuki, and launched with roughly $47M in funding.

Gallant offers ready-to-use stem cell therapies that help pets heal from within, restoring vitality and supporting longer, healthier lives.

Nuvve: Batteries, microgrids and Vehicle-to-Grid (V2G) for Intelligent Electrification; Nuvve powers flexible energy by turning buildings, batteries, and EVs..

Protego Bio is a clinical-stage biotech developing first-in-class small molecule pharmacological chaperones for AL amyloidosis and other protein misfolding diseases.

Brain Corp is an autonomous technology company powering the most proven robots and AI, helping organizations create more productive and intelligent operations.

The most comprehensive executive health assessment — full-body MRI, whole genome sequencing, 120+ biomarkers & AI analysis in one visit. Starting at $8,000.

Founded by Ryne O'Donnell in 2014, who self-funded the company; he briefly sold his majority stake and left in 2017 before returning as chairman.

At Heron, we aim to advance the therapeutic standard of care for patients through a portfolio of best-in-class therapies to deliver medicines that matter.

Price with precision. Negotiate with confidence. Turquoise is the platform 300+ healthcare organizations use to make sense of rates, contracts, and compliance.

Operates as Seasats; CEO and co-founder Mike Flanigan launched the San Diego autonomous-vessel maker in 2020, and it closed a $20 million Series A backed by Philip Bilden.

Discover vMap - The FDA-Cleared Non-Invasive AI-based Arrhythmia Analysis Solution by Vektor Medical. Improve Cardiac Ablation Efficiencies & Outcomes Today.

The Encinitas-based clinical-stage biotech was acquired by Eli Lilly for $1.2 billion in cash, after IPOing on Nasdaq (VTYX) in 2021.

858 Therapeutics (its name references San Diego's 858 area code) has raised $110M across Series A and B rounds led by Versant Ventures and Avidity Partners, with participation from NEA and Insight Partners.

Poseida Therapeutics, a San Diego cell and gene therapy company founded by Eric Ostertag and once listed on Nasdaq as PSTX, was acquired by Roche in a December 2024 tender offer at $9.00/share cash plus a contingent value right.

Avaamme mahdollisuudet ja takaamme sinulle paremman kasvun: Arvo Partners, täyden palvelun digitaalinen markkinointitoimisto ja tuleva strateginen kumppanisi.

AI-powered risk adjustment software designed to increase the profitability of Medicare risk contracts.

The key to managing cancer is early detection. ClearNote Health makes this possible by finding signals of cancer in the blood early

NIS, a US based CRO, provides cryo-EM services to accelerate drug discovery, with structural biology, nanoparticle characterization, and GMP compliant imaging.

FinOps governance for platform teams. Prevent cloud waste and budget overruns before every deploy.

AristaMD empowers primary care providers with excellent specialty care - improving patient outcomes with timely, cost-effective access.

At Daré Bioscience, women’s health is our mission. From clinical trials and non-hormonal contraception to therapies for menopause and vaginal dryness to vaginal health, our research is evidence-based and built exclusively for women.

Tempo Therapeutics is a biotechnology and tissue engineering company based out of San Diego, CA specializing in speeding up patient recovery.

An integrated communications platform using cloud-hosted phone, chat, contact center and analytics to meet the challenges of today’s business.

Primrose Bio specializes in innovative manufacturing solutions for biotherapeutics and vaccines, setting new standards for quality and production efficiency.

JS-WR JV, Inc. does business as Willie's Remedy+, the CBD/THC beverage and wellness product line created by musician Willie Nelson.

In only five minutes and a penny-sized patch, Mindera Health technology captures thousands of RNA transcripts. We enable scalable collection and analysis of individualized genetic information to provide actionable, data-driven decisions for patients, providers and payers.

Founder and CEO Gerald Proehl previously led Santarus Inc. through its $2.6 billion sale to Salix Pharmaceuticals.

Modular Medical was founded by Paul DiPerna, who also founded Tandem Diabetes Care in 2005 and invented its t:slim insulin pump; the company is now led by CEO Jeb Besser.

Cooler Heads is the creator of Amma™, an FDA-cleared scalp cooling system that helps cancer patients reduce hair loss during chemotherapy. Amma delivers hospital-grade cold-cap therapy that’s simple, portable, and patient-first.

BlueNalu, Inc. develops cell-cultivated seafood, beginning with bluefin tuna toro—crafted with care and produced without fishing.

Leading the fight against cancer with targeted stem cell and viral therapies that activate the immune system to destroy solid tumors and metastatic disease.

We bring cell therapies to patients through innovative point-of-care manufacturing solutions.

Founded by Dr. S. Eric Ryan, a former Volcano Corporation VP, Provisio Medical develops intravascular ultrasound smart-catheter technology and has raised tens of millions in venture funding, including backing tied to MedTech Innovator.

A piezoacoustic platform technology that makes the world’s batteries last longer, charge faster, and be safer.

Get instant real-time visibility with EdgeX. Wire-free RTLS, asset tracking, and environmental monitoring. Fast ROI, no IT burden, deployed in hours.

EpiPlex™ assay detects RNA modifications by proximity barcoding and short read RNA sequencing, revealing insights into gene regulation for disease research.

We are a pioneering biotechnology company dedicated to producing innovative solutions to treat traumatic nerve injury.

Vimcal is the world’s fastest calendar, beautifully designed for people who have too many meetings. Drag to share availabilities, schedule across time zones, and see all your Outlook and Google calendars in one view.

Baseline Risk Partners delivers program administration and underwriting expertise in Specialty Property and Workers’ Compensation.

Search engines and social networks are not designed for due diligence. Ferret’s unparalleled AI platform combined with world class information provides you with exclusive relationship intelligence that can help you avoid high-risk individuals and spot promising opportunities.

Cellibre, a San Diego biotech founded by CEO Ben Chiarelli in 2019, closed an $11.5M Series A led by Merida Capital Holdings to commercialize lab-cultured (fermentation-based) cannabinoids.

Technology purpose-built for libraries, archives, and museums for improving Access, Searching, Resource Sharing (interlibrary loan) & Digital Preservation.

Qureator provides integrated human disease model and AI platform to evaluate treatment efficacy in complex disease models.

Measurabl offers comprehensive ESG solutions, empowering businesses with data-driven insights for sustainability & compliance. Learn More

Independa Health Hub® is a simple to use ecosystem of health & wellness benefits on any screen — TV, tablet, computer, or phone. Many benefits absolutely FREE!

Non-toxic deodorants are only good when they're effective. Our plant & mineral based formulas work on all skin types to keep you smelling fresh all day. Aluminum Free Deodorant | Non-Toxic, Paraben & Cruelty Free Free shipping on orders over $25 | Subscribe and save 15%

Gain unprecedented kinetic insights into your CRISPR workflow with the CRISPR QC’s analytics platform

Looking for small business financing? Get approved in 2 minutes or less and get your funds within 24 hours at Cardiff. We have funded over $12 billion for small businesses across the US.

Evofem’s mission is to empower women by providing products that give women the control and flexibility they desire

Serenity is a unified EHS platform built on ServiceNow for incident management, audits, risk assessments, compliance, and cyber risk — with AI-powered safety insights.

selectION Therapeutics' si-544 is a first-in-class Kv1.3 blocker and the first disease modifying treatment for T cell autoimmunity. Autoimmunity affects millions worldwide, but current treatments leave the root cause untouched. si-544 is the first therapy to safely and selectively deactivate disease-causing T cells, while preserving immune competence.

Ospitek empowers surgical centers with real-time IoT and AI-enhanced solutions, improving workflow efficiency, patient care, and staff coordination. Seamlessly integrate with legacy systems and unlock unparalleled operational visibility with Ospitek’s cutting-edge platform.

Co-founded by James Brailean, previously of Snaptrack (the GPS technology company Qualcomm acquired for about $1 billion), alongside Thilo Hoelscher, inventor of the company's SONAS platform technology.

Also known as FuturHealth, this San Diego weight-loss company was co-founded and is led by CEO Luke Mahoney.

Already a publicly traded company on Nasdaq (ticker: GYRE), not a typical early-stage startup; it recently completed an acquisition of Cullgen to create a combined US/China drug-development operation.

Founded and led by Christopher Nero, a San Diego-based finance professional with over 35 years of experience who is also an active private investor in the fintech industry.

Excellos Labs is a cell therapy CDMO offering apheresis collection, PBMC and leukopak processing, T/NK cell isolation, and cGMP manufacturing for biotech and pharma.

As leaders in cathode innovation, we develop materials that drive clean energy solutions. Click here to explore our pioneering work in battery technology.

Transposon Therapeutics, Inc. is developing TPN-101 (also known as Censavudine) and other LINE-1 reverse transcriptase inhibitors for the treatment of rare neurodegenerative diseases such as progressive supranuclear palsy (PSP), amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD).

XiltriX provides 24/7 live agent monitoring for biotech and biopharma labs and facilities that need to prevent sample loss and maintain compliance.

Founded by Dr. Faith H. Barnett, the San Diego biotech has received investment from NuFund Venture Group.

Co-founded by physicists Dr. Massimiliano Di Ventra and Dr. Fabio Traversa alongside serial entrepreneur John Beane, previously a founder of ecoATM; investors include DARPA and Revolution's Rise of the Rest Seed Fund.

Acurion's OncoGaze™ technology delivers critical genomic insights at the biopsy stage, empowering oncologists to make precision therapy a reality for more patients.

Why Use the Virchow Medical Crow’s Nest Biopsy Catchment System? To Improve Core Needle Biopsy Collection, Tissue Management, and Access to Targeted Diagnostics.

SkySafe’s advanced drone detection system and airspace intelligence platform enables organizations to identify, track, analyze, and act on unauthorized drone activity.

Also known as Elevate Dynamics; co-founder Daniel Magy previously founded Citadel Defense Company, a counter-drone defense firm that was later acquired by Blue Halo.

Precision fit and fully alignable. Unbelievably durable, versatile and affordable. It’s time for the UniLeg.

GTR helps home service companies grow with referral software, branded apps, and automated rewards. Turn happy customers into your best lead source.

Aervivo enables our Partners to provide community wide Gigabit managed WiFi, delighting the communities they serve and generating an outstanding 100%+ IRR, quickly.

Certis Oncology Intelligence: predictive AI + advanced cancer models for more insightful data. Translational science, done differently.

Crop Diagnostix uses plant RNA to detect asymptomatic crop stress before symptoms appear. Asymptomatic Agronomy for partners, retailers, and input providers.

The majority of molecules sequenced are uninformative. Jumpcode Genomics is changing that by helping researchers boost usable NGS data.

Meet Cloud RO, an under sink reverse osmosis water system that removes 99% of the toxins in your tap and adds the essential minerals your body needs.

Illudent (operating as Illudent Therapeutics), a San Diego cancer-treatment biotech, has raised roughly $3.25-5.2M in funding from investors including Ulu Ventures and SeedFolio.

Ocelot Bio closed a $36M Series A led by RA Capital Management, Venrock, and Vivo Capital.

Soleic technology is the world's first fully biodegradable, high performance polyurethane material. Plant-based. Zero microplastics.

Self Inspection uses AI trained on 20M+ images to automate vehicle damage detection, condition reports, and CR scoring — built for dealers, fleets, rentals, and lenders.

CARI Health empowers clinicians to personalize methadone dosing for every patient.

Disrupting Tobacco

Founded by Thomas Estok and Dr. Mohamed Ragab, the cancer-drug developer has raised about $59M from investors including Deerfield Management and i&i Biotech Fund.

Founded in 2014 by Patrick Henry, Farooq Anjum, and Jeff Campbell, the agtech soil-sensor company was acquired by Goanna Ag in August 2025.

Growthsayer was founded by Phillip Geltman, a San Diego-based supply chain specialist who originally built the platform to optimize cannabis industry supply chains before expanding into broader retail demand planning.

Hauler Hero is a waste management software solution that helps waste haulers improve their operations, increase efficiency, and reduce costs.

Aethlon Medical is a publicly traded company on Nasdaq under the ticker AEMD.

Streamline your functional health business with Biocanic to get better better scale and outcomes for you and your clients.

Transforming medicine through cellular therapies that restore, regenerate, and repair tissues and organs

RCPS LLC does business as "Bulkhead," an energy drink brand based in Chula Vista, California.

AscentX Medical was founded by Dr. Stefan Lemperle and has raised over $10 million, including a grant from the European Union's Horizon 2020 program.

Operating as Assumable.io, it was co-founded by Ryan Carrillo and Louis Ortiz and drew national coverage (including the New York Times) for its marketplace matching buyers with homes carrying low-rate assumable mortgages.

Founders First Capital Partners - Revenue-Based Funding & Business Advisory

TPT Global Tech is a technology holding company with an emphasis on Media Content, Medical Technology and Telecommunications.

Navega Therapeutics was founded in 2018 by Ana Moreno along with UC San Diego bioengineering professor Prashant Mali, developing gene therapies for chronic pain; it has received a CIRM grant to support its work.

Recruitment CRM for full-time, seasonal, and contract talent. Outreach automation keeps relationships warm and makes rediscovery easy. Works with your ATS.

Discover delicious and nourishing Oatmilks, Almondmilks, Creamers, Coffees, and other natural, non-GMO beverages from Califia Farms. We’re dedicated to powering your wellness transformation by innovating better forms of nourishment with delicious dairy-free plant-based products.

San Diego cancer-drug-discovery company co-founded in 2020 by Pilgrim Jackson (13 years at Celgene) and Afshin Mahmoudi; backers include CONNECT San Diego.

Founded by Austen Sybert in 2020 as an acquisition vehicle that bought and now operates Atlas Crane Service (a crane-services roll-up), rather than a from-scratch startup.

For the ones who believe fun comes in all forms, there’s Improv Cocktails.Our full-flavored, premium non-alcoholic cocktails taste like the real deal, but without the booze. They’re ready to enjoy if you’re going dry, and ready to spike if you’re not.

Led by CEO Jim Saxon, the Southern California holding company partnered with Spain's Mora-Figueroa Domecq, S.L. for tequila product management.

Terafiber was founded by Jim Hanley, a San Diego fiber-infrastructure entrepreneur who had previously founded Netly Fiber, another citywide fiber-network builder, before starting Terafiber in 2023.

Mobile fundraising platform for nonprofits with compliant text messaging, Text-to-Give, and donor engagement. Trusted by 1,000+ organizations.

Alderbuck Energy is modernizing power distribution with solid-state transformer technology built for the electricity demands of AI, EVs, and the modern grid.

GenseeAI, an AI agent infrastructure startup, was co-founded by UC San Diego professor Dr. Yiying Zhang and former Google tech lead Dr. Shengqi Zhu, and is backed by Two Small Fish Ventures.

SmartProperty's Living Reserve Study gives HOA and condo boards real-time reserve fund tracking, capital planning, component inventory, and project management — replacing outdated static reserve studies with a dynamic, always-current platform.

Pi Energy was co-founded by Phil Layton (COO), and the solar technology company has raised capital from retail investors through the equity crowdfunding platform StartEngine.

LJ Watershed LLC is the legal entity behind "Watershed," the restaurant concept from chef Drew Deckman, per Crunchbase.

Berman Medical is a San Diego medical-imaging AI startup founded in 2024 by co-founder and CEO Andrew Hanna, and has raised about $607K to date.

Create engaging, interactive presentations effortlessly with Tiled. Enhance your storytelling and captivate your audience with dynamic, customizable content.

Developing Life-Changing Therapeutics For Our Pets Monoclonal antibodies (mAbs) for modern veterinary practices Developing Life-Changing Therapeutics For Our Pets Monoclonal... Read More

Chefs Life was created in early 2021 by celebrity chef Brian Malarkey (a Top Chef alum and San Diego restaurateur).

Explore Persperion for innovative sweat sensing technology and metabolic health monitoring at your fingertips.

San Diego-based AI-powered polling and community-forum platform for digital publishers, founded by Scott Kaplan, a longtime ESPN 710 LA sports radio host.

Discover the world's most extraordinary collection of perspective-changing rooms, mind-bending installations, and optical illusions.

Our mission is to provide a compassionate, world-class customer experience to the families we serve.

Blending a Japanese style whisky that harmonizes Japanese nature and artisanship

San Diego-based SuperMem was founded by Yu Lu and has received funding including from the National Science Foundation and Techlink Ventures.

Founded by CEO Sucheta Godbole Deshpande, who in 2025/2026 appointed Theresa M. Brady to the company's board of directors as it builds out its AI-driven lifestyle health platform.

We believe that everyone - including those with sensitivities and allergies - should be able to enjoy fragrance. Our non-toxic fragrances are formulated to be free of all 82 EU fragrance allergens and top 9 food allergens, on top of being free from hormone disruptors and carcinogens.

Unlocking the microbiome for better skin health The Human Body Relies On The Microbiome For: Inflammation Control Infection Protection Wound Healing And More The Microbiome Cannot Be Ignored For over 100 years, "skincare" has often treated

Operated as "The BXNG Club," a luxury boxing gym chain in San Diego; the company filed Chapter 11 bankruptcy in June 2024 and abruptly closed all its remaining locations.

Mindfully Crafted Apparel, Surf Craft and Skateboards for the Human Experience™. Mindful Utility™.

Nobility SD, LLC was founded in late 2021 to open a restaurant in La Jolla, San Diego, and later became the subject of a California appellate court case (Nobility SD v. Rocher) stemming from a dispute with the chef who joined the venture in 2022.

M&R Technology, Inc. does business as The Infinity Shield and holds a U.S. patent (invented by Magid Fazel and colleagues) for garage-door safety sensors designed to protect pets and family members from accidental door strikes.

Site Bionics unlocks AI for physical retail, enhancing loss prevention, optimizing store operations, and improving customer experience.

Wallabi is your AI transformation partner. A strategy and implementation firm specializing in AI and data, built by leaders from Tableau, Salesforce, and Google.

Financial Freedom with Bitcoin. The digital assets partner for your business. OTC, Swaps, and Enterprise-Grade Solutions

Nutralase® is a precision enzyme system from Alcheme Bio that removes off-flavors from plant proteins at the molecular source — clean label, drop-in, no reformulation.

RPGMatch, a Los Angeles-based tabletop-gaming matchmaking startup, acquired the long-running gaming community site RPGnet in a 2024 merger, with RPGMatch owner Joaquin Lippincott becoming CEO of the combined company.

AI-Enabled Quality and Regulatory Workflows

Unlocking New Indications for the in vivo CAR-T Modality

Serafin Labs is a San Diego cancer-therapeutics company founded by CEO Sural Ranamukhaarachchi (UC San Diego bioengineering PhD) and affiliated with UCSD's Fraley Lab; it is still operating in stealth mode.

According to its founder's LinkedIn profile, Greenview Labs is a golf technology startup founded by Harrison Fitz.

Intrigue Health, a San Diego home-diagnostics startup, was founded by Dereck Tatman, Ph.D., MBA, who brings over 25 years of industry experience to the company.

Founded by Wharton MBA Paul Dohrenwend; its premium sake made its retail debut at a Costco in San Diego.

Craitor is a San Diego defense startup founded in 2019 by UC San Diego alum Eric Shnell (CEO) and Meher Akhil Birlangi; per Forbes, it has secured $3.3 million in U.S. government contracts.

Influsence's Chief Advisor is Gil Eyal, founder of HYPR, the influencer-marketing platform he built and later sold (to Julius/JW) in 2020.

High quality mRNA for therapeutic application

Bioengineered kidneys for patients with kidney failure

The social app for edge-of-culture communities

Faster processors for solving NP-complete problems

Fermentation-derived natural products to solve health problems

Drop-in Direct Billing SDK for In-App Purchases

We are using the gut microbiome to end cancer.

Oral drugs to halt neurodegeneration

Payments infrastructure for government benefits

LinkedIn content consultancy and scheduling platform for busy founders

Sourcify helps brands manufacture products in Asia.

Powering tomorrow's industrial revolution in space

MedCrypt gives medical device vendors cybersecurity features in a few…

Government-funded online addiction treatment

CRISPR powered Diagnostics with results in minutes.

ML to predict and prevent pregnancy complications