San Diego

Daré Bioscience (Nasdaq: DARE) is a San Diego-based biopharmaceutical company developing and commercializing therapies for women's reproductive and sexual health, an area of medicine it argues has been chronically underfunded relative to its size.

Khartis Therapeutics is a San Diego biotechnology company developing oral small-molecule medicines targeting clinically validated immunology pathways. Its lead program is an oral; selective IGF-1R inh

Amplifica is a San Diego clinical-stage biopharmaceutical company developing injectable treatments for hair loss. Rather than slowing loss; its approach works on the signalling molecules that govern t

Crystalys Therapeutics is a San Diego clinical-stage biotechnology company developing treatments for gout; a disease it argues remains badly served despite being common. Its lead candidate is in pivot

Wugen is an off-the-shelf Cell Therapies for Cancer founded by Matthew Cooper; Todd Fehniger; Melissa Berrien-Elliott and John DiPersio.

Manifold Security provides runtime security for AI agents running on endpoints; monitoring what autonomous agents call and access rather than treating them as ordinary software.

Netradyne engages in improving fleet safety through computer vision and in-depth data analysis.

South 8 Technologies develops LiGas lithium-ion cells built for performance and safety in demanding environments; targeting automotive; defence; robotics and unmanned aerial systems.

Aspen Neuroscience develops autologous iPSC-derived cell replacement therapies for Parkinson’s disease and other CNS disorders.

Seismic is a computer software company co-founded in 2011 by Douglas Winter; Ed Calnan; Fred Xie; Marc Romano; and Nasser Barghouti.

Founded in 2017; Onchilles Pharma is a drug-discovery and development company pioneering first-in-class cytotoxic therapies that selectively kill cancer cells while preserving and activating immune fu

Arnatar Therapeutics develops RNA medicines from a platform it calls DARGER; which pairs highly active siRNA for silencing a gene with ACT-UP1; an antisense technology that does the opposite and incre

Field Medical is a U.S.-based medical device company pioneering pulsed field ablation (PFA) technology for treating cardiac arrhythmias like ventricular tachycardia. Founded by Dr. Steven Mickelsen; i

Founded in 2016 and headquartered in San Diego; Clearspeed provides voice-based risk assessment software that returns real-time risk indicators for insurance; government; defense; and financial-servic

Actio Biosciences is a biotechnology company pioneering precision medicine by developing genetically targeted therapies for both rare and common diseases. Leveraging advanced genomics; Actio aims to t

Coral Vita Inc. is a San Diego-based company founded in 2017 by Gator Halpern.

Koji is a San Diego-based company founded in 2016 by Dmitry Shapiro.

Entos Pharmaceuticals develops nucleic acid-based therapies using its proprietary Fusogenix drug delivery system.

Trust & Will is a digital estate planning platform that offers legally valid estate planning documents that comply with state guidelines.

Pleno is a biotechnology company that aims speeding up disease diagnosis and treatment.

Lomond Therapeutics creates pharmacological platforms that target escape mutations.

Pacific Fusion was founded in 2023 with the mission to power the world with abundant; affordable; clean energy.

Escient Pharmaceuticals is a GPCR-targeted Drugs founded in 2018.

Alterome Therapeutics; Inc. is an oncology Treatments founded in 2021 by Eric Murphy.

Abintus Bio; Inc. is a San Diego-based; preclinical stage gene therapy company focused on the discovery and development of a portfolio of product candidates that are designed to directly reprogram imm

Matrisys Bioscience; Inc. is a dermatology & Skin Care founded in 2015 by Richard Gallo.

Cordial is the cross-channel messaging and data platform for customer-obsessed brands.

Epic Sciences is a San Diego-based company founded in 2008 by Jorge Nieva; David Nelson and Peter Kuhn.

Housecall Pro is a company founded in 2013 by Adam Perry-Pelletier; Ian Heidt; Roland Ligtenberg; Reza Olfat and Chris Zwickilton.

Galley Solutions is a San Diego-based company.

Concert Health delivers behavioural health services inside primary care using the collaborative care model; embedding its own clinicians alongside medical groups and health systems so that depression

The Honest Kitchen makes human-grade pet food for dogs and cats from whole food ingredients.

Molecular Assemblies; Inc. is an enzymatic DNA synthesis technology founded in 2013 by Curt Becker; Bill Efcavitch and William Efcavitch.

A biotechnology company focused on the discovery and development of next-generation therapeutics.

Fermata Energy is a vehicle-to-everything technology business founded in 2010 by David Slutzky and John Wheeler. Its platform combines bidirectional chargers; forecasting and energy-management softwar

Daasity is a San Diego-based company founded in 2017.

Kneron develops and provides edge AI-based integrated software and hardware for a variety of industries.

Developer of a liquid biopsy technology designed to revolutionize the early detection of cancer in pets.

Iru; formerly Kandji; provides Apple device management for enterprises; unifying endpoint management; compliance and identity so IT and security teams administer devices and the access they carry from

Workiz sells field service management software for home service businesses; covering job scheduling; dispatch; invoicing; payments and performance tracking.

CloudBeds is a San Diego-based company founded in 2012 by Richard Castle and Adam Harris.

Mango Technologies; Inc. is a San Diego-based company founded in 2016.

Shoreline Biosciences; Inc. is a Cell-Based Immunotherapies; founded in 2020. It has raised $229M across 4 funding rounds; most recently a $140M in November 2021; from investors including Janus Capita

A project management platform with customization tailored to each individual project and team.

Clarify Medical is a developer of a handheld medical device used to treat psoriasis; eczema; and vitiligo .

MosaicML is a San Francisco-based company offering a generative AI platform for enterprises to build their own AI systems.

Truepic is a San Diego content-authenticity company founded in 2015. Its Truepic Vision platform captures photos and video with verifiable provenance; tamper detection and C2PA-compatible credentials

GoFormz Inc.; an American software company; provides a mobile forms and data capture platform via their web interface and mobile app.

Application composition platform for building applications on Kubernetes using open-source software.

Genomatica; which trades as Geno; is a San Diego industrial biotechnology company founded in 2000 by Christophe Schilling. It engineers micro-organisms and the bioprocesses around them so that widely

Kumquat Biosciences is a San Diego-based biotechnology company focused on the research and development of oncology medicines.

Nanocellect biomedical is a life science tools company manufacturing cell sorters using proprietary technology.

Aristea Therapeutics is a small Molecules founded in 2018.

Sendlane is a San Diego-based company founded in 2013.

Developer of therapeutic discovery quantum molecular simulation engine designed to accelerate molecular discovery.

Element Biosciences is a genetic analysis tools.

ViaCyte is a biotechnology company using stem cells to create pancreatic beta cell precursors for treating diabetes.

Operator of a biotechnology company intended to improve outcomes for people with cancer. The company offers a pipeline against validated oncology targets to deliver radioisotopes that emit alpha parti

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