Health tech, medical devices, and diagnostics startups. San Diego's decades-old biotech corridor makes healthcare its deepest startup category by far.

Developing the next generation of oncology therapies for patients.
We're dedicated to defeating cancer with therapies that target disease, not immune systems. Find our investigational immunotherapy and cell therapy products.
Novartis completed its acquisition of Avidity Biosciences in 2026, folding the San Diego RNA-therapeutics company into its late-stage neuroscience pipeline.

Crinetics is here for endocrine disease patients who are eager to find therapies that provide effective disease control and more simplicity in their lives.

Iambic has created a cutting-edge AI-driven platform to tackle the most challenging design problems in drug discovery and address unmet patient need.
Merck agreed to acquire the San Diego biotech for approximately $9.2 billion in November 2025.
Founded in 2012 by two UC San Diego PhD alumni, Jared Tangney and Josh Windmiller, originally under the name Electrozyme.
Co-founded by Drew Weissman, the 2023 Nobel Prize winner in Physiology or Medicine for mRNA vaccine research, alongside CAR-T pioneer Carl June; the company was later acquired by AbbVie.


Science Seralutinib Seralutinib is an inhaled PDGFRα/β, CSF1R, and c‑KIT inhibitor designed to be delivered via dry powder inhaler for the potential treatment of pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease (PH-ILD).

Founded by Ken Song and launched with over $370 million (later exceeding $500 million) from investors including Venrock Healthcare Capital Partners, RA Capital Management, and Fairmount.

Has raised over $350 million from major healthcare investors including OrbiMed, BlackRock, and Bain Capital Life Sciences.

ABA therapy and comprehensive autism care for children, from diagnosis through developmental and medical therapy. Physician-led and in-network. Find a center near you.

We are on a mission to exponentially improve the number of quality years for patients.

We are a biopharmaceutical company focused on the development of proprietary cannabinoid derivatives for the treatment of glaucoma and other diseases with significant unmet medical needs. Our innovative approach to drug development combines strong science with the drive to find solutions where the need is the greatest.

Our mission is to realize the promise of precision medicines to help patients with cancer lead better, longer lives.

Endeavor BioMedicines is a clinical-stage biotechnology company developing transformational medicines for life-threatening diseases.
A Foresite Labs-incubated biotech backed by Foresite Capital, Qiming Venture Partners, and Samsara BioCapital that raised over $100M before being folded into Candid Therapeutics' $370M launch in 2024.

Autobahn aims to improve life health for people affected by CNS disorders by driving the regenerative power of the human body.

We at Boundless Bio are pioneers in understanding and treating the most intractable cancers. We have charted a new spatial map of the cancer genome within cancer cells and are harnessing our scientific founders’ discoveries about “extrachromosomal DNA,” or ecDNA, to drive a revolution in cancer therapeutics.
TRC 2004 was co-founded by Third Rock Ventures and Two River, the same investor group behind Kite Pharma (sold to Gilead for roughly $11.9B), and later emerged publicly as Candid Therapeutics with a $370M capital raise.
Aardvark Therapeutics is a clinical-stage biopharmaceutical company developing novel, small-molecule therapies designed to inhibit hunger and treat metabolic
Discover how Bionano is striving to elevate health and wellness for all through optical genome mapping (OGM) solutions that transform the way the world sees the genome.
Gene therapy company that emerged from stealth in June 2023 with a $51M Series A co-led by Westlake Village BioPartners, developing AAV-based genetic medicines for muscle and heart disease.
San Diego biologics company led by CEO Krisztina Zsebo, PhD, developing vascular biologic therapies for ischemic stroke and acute cardiovascular disease.

Plexium is a next-generation targeted protein degradation (TPD) company that discovers Monovalent Direct Degraders and Molecular Glues.
SRT Therapeutics was founded in 2024 by former leaders of Prometheus Biosciences, including President & CEO Lauren Otsuki, and launched with roughly $47M in funding.
Protego Bio is a clinical-stage biotech developing first-in-class small molecule pharmacological chaperones for AL amyloidosis and other protein misfolding diseases.

The most comprehensive executive health assessment — full-body MRI, whole genome sequencing, 120+ biomarkers & AI analysis in one visit. Starting at $8,000.
At Heron, we aim to advance the therapeutic standard of care for patients through a portfolio of best-in-class therapies to deliver medicines that matter.

Discover vMap - The FDA-Cleared Non-Invasive AI-based Arrhythmia Analysis Solution by Vektor Medical. Improve Cardiac Ablation Efficiencies & Outcomes Today.
858 Therapeutics (its name references San Diego's 858 area code) has raised $110M across Series A and B rounds led by Versant Ventures and Avidity Partners, with participation from NEA and Insight Partners.
Poseida Therapeutics, a San Diego cell and gene therapy company founded by Eric Ostertag and once listed on Nasdaq as PSTX, was acquired by Roche in a December 2024 tender offer at $9.00/share cash plus a contingent value right.

AI-powered risk adjustment software designed to increase the profitability of Medicare risk contracts.

The key to managing cancer is early detection. ClearNote Health makes this possible by finding signals of cancer in the blood early


AristaMD empowers primary care providers with excellent specialty care - improving patient outcomes with timely, cost-effective access.
At Daré Bioscience, women’s health is our mission. From clinical trials and non-hormonal contraception to therapies for menopause and vaginal dryness to vaginal health, our research is evidence-based and built exclusively for women.
Tempo Therapeutics is a biotechnology and tissue engineering company based out of San Diego, CA specializing in speeding up patient recovery.
Primrose Bio specializes in innovative manufacturing solutions for biotherapeutics and vaccines, setting new standards for quality and production efficiency.
In only five minutes and a penny-sized patch, Mindera Health technology captures thousands of RNA transcripts. We enable scalable collection and analysis of individualized genetic information to provide actionable, data-driven decisions for patients, providers and payers.

Cooler Heads is the creator of Amma™, an FDA-cleared scalp cooling system that helps cancer patients reduce hair loss during chemotherapy. Amma delivers hospital-grade cold-cap therapy that’s simple, portable, and patient-first.
Leading the fight against cancer with targeted stem cell and viral therapies that activate the immune system to destroy solid tumors and metastatic disease.

We bring cell therapies to patients through innovative point-of-care manufacturing solutions.
EpiPlex™ assay detects RNA modifications by proximity barcoding and short read RNA sequencing, revealing insights into gene regulation for disease research.

We are a pioneering biotechnology company dedicated to producing innovative solutions to treat traumatic nerve injury.

Cellibre, a San Diego biotech founded by CEO Ben Chiarelli in 2019, closed an $11.5M Series A led by Merida Capital Holdings to commercialize lab-cultured (fermentation-based) cannabinoids.
Qureator provides integrated human disease model and AI platform to evaluate treatment efficacy in complex disease models.

Independa Health Hub® is a simple to use ecosystem of health & wellness benefits on any screen — TV, tablet, computer, or phone. Many benefits absolutely FREE!
Gain unprecedented kinetic insights into your CRISPR workflow with the CRISPR QC’s analytics platform
Evofem’s mission is to empower women by providing products that give women the control and flexibility they desire

selectION Therapeutics' si-544 is a first-in-class Kv1.3 blocker and the first disease modifying treatment for T cell autoimmunity. Autoimmunity affects millions worldwide, but current treatments leave the root cause untouched. si-544 is the first therapy to safely and selectively deactivate disease-causing T cells, while preserving immune competence.

Ospitek empowers surgical centers with real-time IoT and AI-enhanced solutions, improving workflow efficiency, patient care, and staff coordination. Seamlessly integrate with legacy systems and unlock unparalleled operational visibility with Ospitek’s cutting-edge platform.
Already a publicly traded company on Nasdaq (ticker: GYRE), not a typical early-stage startup; it recently completed an acquisition of Cullgen to create a combined US/China drug-development operation.

Excellos Labs is a cell therapy CDMO offering apheresis collection, PBMC and leukopak processing, T/NK cell isolation, and cGMP manufacturing for biotech and pharma.
Transposon Therapeutics, Inc. is developing TPN-101 (also known as Censavudine) and other LINE-1 reverse transcriptase inhibitors for the treatment of rare neurodegenerative diseases such as progressive supranuclear palsy (PSP), amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD).

XiltriX provides 24/7 live agent monitoring for biotech and biopharma labs and facilities that need to prevent sample loss and maintain compliance.

Founded by Dr. Faith H. Barnett, the San Diego biotech has received investment from NuFund Venture Group.

Acurion's OncoGaze™ technology delivers critical genomic insights at the biopsy stage, empowering oncologists to make precision therapy a reality for more patients.

Why Use the Virchow Medical Crow’s Nest Biopsy Catchment System? To Improve Core Needle Biopsy Collection, Tissue Management, and Access to Targeted Diagnostics.
Precision fit and fully alignable. Unbelievably durable, versatile and affordable. It’s time for the UniLeg.

Certis Oncology Intelligence: predictive AI + advanced cancer models for more insightful data. Translational science, done differently.
The majority of molecules sequenced are uninformative. Jumpcode Genomics is changing that by helping researchers boost usable NGS data.

Illudent (operating as Illudent Therapeutics), a San Diego cancer-treatment biotech, has raised roughly $3.25-5.2M in funding from investors including Ulu Ventures and SeedFolio.
Ocelot Bio closed a $36M Series A led by RA Capital Management, Venrock, and Vivo Capital.

CARI Health empowers clinicians to personalize methadone dosing for every patient.
Founded by Thomas Estok and Dr. Mohamed Ragab, the cancer-drug developer has raised about $59M from investors including Deerfield Management and i&i Biotech Fund.
Aethlon Medical is a publicly traded company on Nasdaq under the ticker AEMD.
Transforming medicine through cellular therapies that restore, regenerate, and repair tissues and organs
AscentX Medical was founded by Dr. Stefan Lemperle and has raised over $10 million, including a grant from the European Union's Horizon 2020 program.
Navega Therapeutics was founded in 2018 by Ana Moreno along with UC San Diego bioengineering professor Prashant Mali, developing gene therapies for chronic pain; it has received a CIRM grant to support its work.
Discover delicious and nourishing Oatmilks, Almondmilks, Creamers, Coffees, and other natural, non-GMO beverages from Califia Farms. We’re dedicated to powering your wellness transformation by innovating better forms of nourishment with delicious dairy-free plant-based products.

Berman Medical is a San Diego medical-imaging AI startup founded in 2024 by co-founder and CEO Andrew Hanna, and has raised about $607K to date.

Developing Life-Changing Therapeutics For Our Pets Monoclonal antibodies (mAbs) for modern veterinary practices Developing Life-Changing Therapeutics For Our Pets Monoclonal... Read More

Explore Persperion for innovative sweat sensing technology and metabolic health monitoring at your fingertips.

Our mission is to provide a compassionate, world-class customer experience to the families we serve.

Unlocking the microbiome for better skin health The Human Body Relies On The Microbiome For: Inflammation Control Infection Protection Wound Healing And More The Microbiome Cannot Be Ignored For over 100 years, "skincare" has often treated
Operated as "The BXNG Club," a luxury boxing gym chain in San Diego; the company filed Chapter 11 bankruptcy in June 2024 and abruptly closed all its remaining locations.

Unlocking New Indications for the in vivo CAR-T Modality
Serafin Labs is a San Diego cancer-therapeutics company founded by CEO Sural Ranamukhaarachchi (UC San Diego bioengineering PhD) and affiliated with UCSD's Fraley Lab; it is still operating in stealth mode.

Intrigue Health, a San Diego home-diagnostics startup, was founded by Dereck Tatman, Ph.D., MBA, who brings over 25 years of industry experience to the company.

High quality mRNA for therapeutic application

Oral drugs to halt neurodegeneration

We are using the gut microbiome to end cancer.

CRISPR powered Diagnostics with results in minutes.


Government-funded online addiction treatment

MedCrypt gives medical device vendors cybersecurity features in a few…


Fermentation-derived natural products to solve health problems
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ML to predict and prevent pregnancy complications


Bioengineered kidneys for patients with kidney failure