Healthcare
Health tech, medical devices, and diagnostics startups. San Diego's decades-old biotech corridor makes healthcare its deepest startup category by far.
The breakdown
79 of 99 companies have disclosed funding, $4.76B combined, 21 at Series A stage, making up 25% of the 400 San Diego startups on file across every industry, founding dates span 2002-2026.
Companies
Daré Bioscience (Nasdaq: DARE) is a San Diego-based biopharmaceutical company developing and commercializing therapies for women's reproductive and sexual health, an area of medicine it argues has been chronically underfunded relative to its size.
CLARIFY MEDICAL; INC. is a San Diego-based healthcare company.
PatientSafe Solutions is a San Diego-based company founded in 2002.
Suneva Medical is an aesthetic Medicine founded in 2009.
A company that develops therapeutics for the treatment of cancer

Developing the next generation of oncology therapies for patients.
Mirador Therapeutics is focused on discovering and developing precision medicines for immune-mediated inflammatory and fibrotic diseases using its Mirador360™ engine, which harnesses biology, multi-modal data, AI, and advanced analytics.
Avidity Biosciences is a company driven by the mission to profoundly improve people's lives by revolutionizing a new class of targeted RNA therapeutics through its Antibody Oligonucleotide Conjugates (AOC™) platform.

Iambic has created a cutting-edge AI-driven platform to tackle the most challenging design problems in drug discovery and address unmet patient need.
Merck agreed to acquire the San Diego biotech for approximately $9.2 billion in November 2025.
Biolinq Inc. develops the Biolinq Shine™ sensor, which is a fully autonomous, needle-free glucose sensor that integrates glucose, activity, and sleep information.
Co-founded by Drew Weissman, the 2023 Nobel Prize winner in Physiology or Medicine for mRNA vaccine research, alongside CAR-T pioneer Carl June; the company was later acquired by AbbVie.

Rakuten Medical is developing the Alluminox® platform, an investigational platform based on photoimmunotherapy, to transform cancer treatments.
Founded by Ken Song and launched with over $370 million (later exceeding $500 million) from investors including Venrock Healthcare Capital Partners, RA Capital Management, and Fairmount.

ADARx Pharmaceuticals, Inc. is a company that develops RNA medicines leveraging RNA science and proprietary targeted delivery platforms to silence the underlying cause of disease.

ABA therapy and comprehensive autism care for children, from diagnosis through developmental and medical therapy. Physician-led and in-network. Find a center near you.

Endeavor BioMedicines is a clinical-stage biotechnology company developing transformational medicines for life-threatening diseases.
A Foresite Labs-incubated biotech backed by Foresite Capital, Qiming Venture Partners, and Samsara BioCapital that raised over $100M before being folded into Candid Therapeutics' $370M launch in 2024.

Autobahn aims to improve life health for people affected by CNS disorders by driving the regenerative power of the human body.
TRC 2004 was co-founded by Third Rock Ventures and Two River, the same investor group behind Kite Pharma (sold to Gilead for roughly $11.9B), and later emerged publicly as Candid Therapeutics with a $370M capital raise.
Gene therapy company that emerged from stealth in June 2023 with a $51M Series A co-led by Westlake Village BioPartners, developing AAV-based genetic medicines for muscle and heart disease.
VST BIO Corp is a biotechnology company developing first-in-class antibody drugs for the treatment of inflammatory and cardiovascular diseases, including stroke and acute myocardial infarction, as well as sepsis.

Plexium is a next-generation targeted protein degradation (TPD) company that discovers Monovalent Direct Degraders and Molecular Glues.
SRT Therapeutics was founded in 2024 by former leaders of Prometheus Biosciences, including President & CEO Lauren Otsuki, and launched with roughly $47M in funding.
Protego Bio is a clinical-stage biotech developing first-in-class small molecule pharmacological chaperones for AL amyloidosis and other protein misfolding diseases.

The most comprehensive executive health assessment — full-body MRI, whole genome sequencing, 120+ biomarkers & AI analysis in one visit. Starting at $8,000.

Discover vMap - The FDA-Cleared Non-Invasive AI-based Arrhythmia Analysis Solution by Vektor Medical. Improve Cardiac Ablation Efficiencies & Outcomes Today.
858 Therapeutics (its name references San Diego's 858 area code) has raised $110M across Series A and B rounds led by Versant Ventures and Avidity Partners, with participation from NEA and Insight Partners.
Poseida Therapeutics, a San Diego cell and gene therapy company founded by Eric Ostertag and once listed on Nasdaq as PSTX, was acquired by Roche in a December 2024 tender offer at $9.00/share cash plus a contingent value right.

AI-powered risk adjustment software designed to increase the profitability of Medicare risk contracts.

The key to managing cancer is early detection. ClearNote Health makes this possible by finding signals of cancer in the blood early

Rejuvenate Bio uses a gene therapy approach to treat chronic, age-related diseases by targeting the root causes of aging to create treatments for chronic conditions affecting both companion animals and humans.

AristaMD empowers primary care providers with excellent specialty care - improving patient outcomes with timely, cost-effective access.
Tempo Therapeutics is a biotechnology and tissue engineering company based out of San Diego, CA specializing in speeding up patient recovery.
Primrose Bio specializes in innovative manufacturing solutions for biotherapeutics and vaccines, setting new standards for quality and production efficiency.
In only five minutes and a penny-sized patch, Mindera Health technology captures thousands of RNA transcripts. We enable scalable collection and analysis of individualized genetic information to provide actionable, data-driven decisions for patients, providers and payers.

Cooler Heads is the creator of Amma™, an FDA-cleared scalp cooling system that helps cancer patients reduce hair loss during chemotherapy. Amma delivers hospital-grade cold-cap therapy that’s simple, portable, and patient-first.

We bring cell therapies to patients through innovative point-of-care manufacturing solutions.
EpiPlex™ assay detects RNA modifications by proximity barcoding and short read RNA sequencing, revealing insights into gene regulation for disease research.

We are a pioneering biotechnology company dedicated to producing innovative solutions to treat traumatic nerve injury.

Cellibre, Inc. uses biology as a manufacturing technology, leveraging nature to create sustainable products through strain engineering, biochemistry, and precision fermentation.
Qureator provides integrated human disease model and AI platform to evaluate treatment efficacy in complex disease models.

Independa Health Hub® is a simple to use ecosystem of health & wellness benefits on any screen — TV, tablet, computer, or phone. Many benefits absolutely FREE!
Gain unprecedented kinetic insights into your CRISPR workflow with the CRISPR QC’s analytics platform

selectION Therapeutics' si-544 is a first-in-class Kv1.3 blocker and the first disease modifying treatment for T cell autoimmunity. Autoimmunity affects millions worldwide, but current treatments leave the root cause untouched. si-544 is the first therapy to safely and selectively deactivate disease-causing T cells, while preserving immune competence.

Ospitek empowers surgical centers with real-time IoT and AI-enhanced solutions, improving workflow efficiency, patient care, and staff coordination. Seamlessly integrate with legacy systems and unlock unparalleled operational visibility with Ospitek’s cutting-edge platform.

Excellos Labs is a cell therapy CDMO offering apheresis collection, PBMC and leukopak processing, T/NK cell isolation, and cGMP manufacturing for biotech and pharma.
Transposon Therapeutics, Inc. is developing TPN-101 (also known as Censavudine) and other LINE-1 reverse transcriptase inhibitors for the treatment of rare neurodegenerative diseases such as progressive supranuclear palsy (PSP), amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD).

XiltriX provides 24/7 live agent monitoring for biotech and biopharma labs and facilities that need to prevent sample loss and maintain compliance.

Resolute Science, Inc. is a biotechnology company developing a pipeline of first-in-class synthetic drug conjugates, specifically Macrophage-Targeted Conjugates (MAC-TACs), for the treatment of solid tumors.

Acurion's OncoGaze™ technology delivers critical genomic insights at the biopsy stage, empowering oncologists to make precision therapy a reality for more patients.

Why Use the Virchow Medical Crow’s Nest Biopsy Catchment System? To Improve Core Needle Biopsy Collection, Tissue Management, and Access to Targeted Diagnostics.
Precision fit and fully alignable. Unbelievably durable, versatile and affordable. It’s time for the UniLeg.

Certis Oncology Intelligence: predictive AI + advanced cancer models for more insightful data. Translational science, done differently.
The majority of molecules sequenced are uninformative. Jumpcode Genomics is changing that by helping researchers boost usable NGS data.

Illudent (operating as Illudent Therapeutics), a San Diego cancer-treatment biotech, has raised roughly $3.25-5.2M in funding from investors including Ulu Ventures and SeedFolio.
Ocelot Bio closed a $36M Series A led by RA Capital Management, Venrock, and Vivo Capital.

CARI Health empowers clinicians to personalize methadone dosing for every patient.
Dracen Pharmaceuticals is a private pharmaceutical company leveraging immuno-metabolism to create new cancer treatments, with their lead candidate, sirpiglenastat (DRP-104), being a unique glutamine inhibitor.
Transforming medicine through cellular therapies that restore, regenerate, and repair tissues and organs
AscentX Medical, Inc. is dedicated to improving quality of life through injectable regenerative therapy focusing on advanced soft tissue engineering using autologous tissue engineering technology with injectable microspheres.
Navega Therapeutics is harnessing the precision of zinc-finger and CRISPR based epigenome regulation to enable next-generation gene therapies for chronic pain and precision pain management.
Discover delicious and nourishing Oatmilks, Almondmilks, Creamers, Coffees, and other natural, non-GMO beverages from Califia Farms. We’re dedicated to powering your wellness transformation by innovating better forms of nourishment with delicious dairy-free plant-based products.

Berman Medical is building the image-guided navigation layer for point-of-care procedures to make patient-specific 3D visualization and navigation accessible.

Developing Life-Changing Therapeutics For Our Pets Monoclonal antibodies (mAbs) for modern veterinary practices Developing Life-Changing Therapeutics For Our Pets Monoclonal... Read More

Explore Persperion for innovative sweat sensing technology and metabolic health monitoring at your fingertips.

Our mission is to provide a compassionate, world-class customer experience to the families we serve.

Unlocking the microbiome for better skin health The Human Body Relies On The Microbiome For: Inflammation Control Infection Protection Wound Healing And More The Microbiome Cannot Be Ignored For over 100 years, "skincare" has often treated
Operated as "The BXNG Club," a luxury boxing gym chain in San Diego; the company filed Chapter 11 bankruptcy in June 2024 and abruptly closed all its remaining locations.

Unlocking New Indications for the in vivo CAR-T Modality
Serafin Labs is a San Diego cancer-therapeutics company founded by CEO Sural Ranamukhaarachchi (UC San Diego bioengineering PhD) and affiliated with UCSD's Fraley Lab; it is still operating in stealth mode.

Intrigue Health aims to empower patients and healthcare providers with home diagnostics.

MedicalMex helps and protects international patients traveling to Mexico for affordable medical services, including weight loss surgery, plastic surgery, pain management, hair restoration, dental, vascular, more procedures, orthopedic surgery, and general surgery.

Novoron Bioscience is pioneering lipoprotein-receptor drug development to repair damage and degeneration of the brain, spinal cord, and beyond, with therapies to block the spread of prion-like proteins and enhance spinal cord regeneration.

Kenai Therapeutics is a clinical-stage biotechnology company advancing off-the-shelf dopamine neuron replacement cell therapies and gene-modified medicines to cure neurological conditions.

Neomorph develops molecular glue degraders to target and destroy disease-causing proteins by engineering neomorphic protein surfaces.

Sidewinder Therapeutics pioneers the next generation of bispecific antibody-drug conjugates (ADCs) to expand the therapeutic window for patients with difficult-to-treat cancers.

RyboDyn is pioneering immunotherapy development by unlocking the dark proteome with its proprietary RyboCypher™ technology to reveal hidden targets and transform biological signals into breakthrough therapies.
Replicate Bioscience leverages self-replicating RNA (srRNA) vectors to advance treatments across therapeutic areas like infectious disease, oncology, and autoimmune disorders.

Recludix Pharma is developing new oral precision medicines with selective inhibitors to tackle protein targets for people living with inflammatory diseases.
Primmune Therapeutics is a clinical-stage biotechnology company focused on developing systemic cancer immunotherapies that activate the immune system in a precise and controlled manner.

Sharpen DTX, by Resiliency Technologies, Inc., provides mental health literacy tools and prevention toolkits for schools, families, colleges, and community organizations to improve mental wellness and resiliency.

Oral drugs to halt neurodegeneration

We are using the gut microbiome to end cancer.


Fermentation-derived natural products to solve health problems


Bioengineered kidneys for patients with kidney failure

High quality mRNA for therapeutic application
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ML to predict and prevent pregnancy complications

MedCrypt gives medical device vendors cybersecurity features in a few…


Government-funded online addiction treatment


CRISPR powered Diagnostics with results in minutes.