SoCal.StartupsBe an early user
SAN DIEGO

B2B

Business software and services sold to other companies, built in San Diego.

108
companies
$2.09B
total raised
Series G$1.19B
Shield AI Inc
San Diego, CA

Shield AI is a defense-tech company building the world's best AI pilots and next-generation aircraft.

Series GB2B
Series B$130.0M
DroneBase, Inc.
San Diego, CA
Series BB2B
Series C$126.8M
Drata Inc.
San Diego, CA · Founded 2020
Series CB2B
Series A$83.0M
Firestorm Labs, Inc.
San Diego, CA · Founded 2022

Firestorm Labs - Democratize the fight with radically-affordable, mission-adaptable power for air, land, and sea.

Series AB2B
Series B$56.0M
Fabric8Labs, Inc.
San Diego, CA

Electrochemical Additive Manufacturing Mass Production of Next Generation Components High-Resolution Metal 3D Printing at Scale Electrochemical Additive Manufacturing (ECAM) is... Read More

Series BB2B
Series A$35.6M
Gallant Pet, Inc.
San Diego, CA

Gallant offers ready-to-use stem cell therapies that help pets heal from within, restoring vitality and supporting longer, healthier lives.

Series AB2B
Series A$32.1M
Brain Corp
San Diego, CA

Brain Corp is an autonomous technology company powering the most proven robots and AI, helping organizations create more productive and intelligent operations.

Series AB2B
Series B$30.3M
Sol-ti, Inc.
San Diego, CA

Founded by Ryne O'Donnell in 2014, who self-funded the company; he briefly sold his majority stake and left in 2017 before returning as chairman.

Series BB2B
Series B$30.0M
Turquoise Health Co.
San Diego, CA · Founded 2020

Price with precision. Negotiate with confidence. Turquoise is the platform 300+ healthcare organizations use to make sense of rates, contracts, and compliance.

Series BB2B
Series A$29.1M
SeaSatellites, Inc.
San Diego, CA · Founded 2020

Operates as Seasats; CEO and co-founder Mike Flanigan launched the San Diego autonomous-vessel maker in 2020, and it closed a $20 million Series A backed by Philip Bilden.

Series AB2B
Series B$27.0M
Ventyx Biosciences, Inc.
San Diego, CA

The Encinitas-based clinical-stage biotech was acquired by Eli Lilly for $1.2 billion in cash, after IPOing on Nasdaq (VTYX) in 2021.

Series BB2B
$24.9M
Arvo Partners, LLC
San Diego, CA · Founded 2022

Avaamme mahdollisuudet ja takaamme sinulle paremman kasvun: Arvo Partners, täyden palvelun digitaalinen markkinointitoimisto ja tuleva strateginen kumppanisi.

B2B
Seed$19.7M
NanoImaging Services, Inc.
San Diego, CA

NIS, a US based CRO, provides cryo-EM services to accelerate drug discovery, with structural biology, nanoparticle characterization, and GMP compliant imaging.

SeedB2B
Series A$18.8M
Infracost Inc
San Diego, CA · Founded 2021

FinOps governance for platform teams. Prevent cloud waste and budget overruns before every deploy.

Series AB2B
Series B$15.8M
Verve Cloud, Inc.
San Diego, CA

An integrated communications platform using cloud-hosted phone, chat, contact center and analytics to meet the challenges of today’s business.

Series BB2B
Series A$14.5M
JS-WR JV, INC.
San Diego, CA · Founded 2025

JS-WR JV, Inc. does business as Willie's Remedy+, the CBD/THC beverage and wellness product line created by musician Willie Nelson.

Series AB2B
Series E$12.7M
Dermata Therapeutics, Inc.
San Diego, CA · Founded 2021

Founder and CEO Gerald Proehl previously led Santarus Inc. through its $2.6 billion sale to Salix Pharmaceuticals.

Series EB2B
Series A$12.0M
Modular Medical, Inc.
San Diego, CA

Modular Medical was founded by Paul DiPerna, who also founded Tandem Diabetes Care in 2005 and invented its t:slim insulin pump; the company is now led by CEO Jeb Besser.

Series AB2B
Series B$10.5M
BlueNalu, Inc.
San Diego, CA

BlueNalu, Inc. develops cell-cultivated seafood, beginning with bluefin tuna toro—crafted with care and produced without fishing.

Series BB2B
Seed$9.8M
Provisio Medical Technologies Corp
San Diego, CA · Founded 2025

Founded by Dr. S. Eric Ryan, a former Volcano Corporation VP, Provisio Medical develops intravascular ultrasound smart-catheter technology and has raised tens of millions in venture funding, including backing tied to MedTech Innovator.

SeedB2B
Seed$8.8M
HypeVR
San Diego, CA
SeedB2B
Series A$8.5M
Luxvitae Therapeutics Inc.
San Diego, CA
Series AB2B
Series A$8.5M
Sonocharge Energy, Inc.
San Diego, CA · Founded 2022

A piezoacoustic platform technology that makes the world’s batteries last longer, charge faster, and be safer.

Series AB2B
Series A$8.5M
EdgeX, Inc.
San Diego, CA

Get instant real-time visibility with EdgeX. Wire-free RTLS, asset tracking, and environmental monitoring. Fast ROI, no IT burden, deployed in hours.

Series AB2B
Series B$7.3M
Provisio Medical, Inc.
San Diego, CA
Series BB2B
Seed$6.9M
Vimcal Inc.
San Diego, CA

Vimcal is the world’s fastest calendar, beautifully designed for people who have too many meetings. Drag to share availabilities, schedule across time zones, and see all your Outlook and Google calendars in one view.

SeedB2B
$6.8M
Ferret Systems Inc.
San Diego, CA

Search engines and social networks are not designed for due diligence. Ferret’s unparalleled AI platform combined with world class information provides you with exclusive relationship intelligence that can help you avoid high-risk individuals and spot promising opportunities.

B2B
$6.7M
Soutron Holdings LLC
San Diego, CA · Founded 2025

Technology purpose-built for libraries, archives, and museums for improving Access, Searching, Resource Sharing (interlibrary loan) & Digital Preservation.

B2B
Series D$6.5M
Measurabl, Inc.
San Diego, CA

Measurabl offers comprehensive ESG solutions, empowering businesses with data-driven insights for sustainability & compliance. Learn More

Series DB2B
Seed$6.4M
HUME SUPERNATURAL, INC.
San Diego, CA · Founded 2019

Non-toxic deodorants are only good when they're effective. Our plant & mineral based formulas work on all skin types to keep you smelling fresh all day. Aluminum Free Deodorant | Non-Toxic, Paraben & Cruelty Free Free shipping on orders over $25 | Subscribe and save 15%

SeedB2B
Seed$5.5M
Serenity EHS Inc.
San Diego, CA · Founded 2019

Serenity is a unified EHS platform built on ServiceNow for incident management, audits, risk assessments, compliance, and cyber risk — with AI-powered safety insights.

SeedB2B
$5.3M
Burl Concepts, Inc.
San Diego, CA

Co-founded by James Brailean, previously of Snaptrack (the GPS technology company Qualcomm acquired for about $1 billion), alongside Thilo Hoelscher, inventor of the company's SONAS platform technology.

B2B
Seed$5.0M
FUTURCO HEALTH TECHNOLOGIES, INC.
San Diego, CA

Also known as FuturHealth, this San Diego weight-loss company was co-founded and is led by CEO Luke Mahoney.

SeedB2B
Series D$4.9M
WILDCAT DISCOVERY TECHNOLOGIES, INC.
San Diego, CA

As leaders in cathode innovation, we develop materials that drive clean energy solutions. Click here to explore our pioneering work in battery technology.

Series DB2B
Seed$4.4M
MemComputing, Inc.
San Diego, CA

Co-founded by physicists Dr. Massimiliano Di Ventra and Dr. Fabio Traversa alongside serial entrepreneur John Beane, previously a founder of ecoATM; investors include DARPA and Revolution's Rise of the Rest Seed Fund.

SeedB2B
Series B$4.0M
SkySafe, Inc.
San Diego, CA

SkySafe’s advanced drone detection system and airspace intelligence platform enables organizations to identify, track, analyze, and act on unauthorized drone activity.

Series BB2B
Seed$4.0M
SRE Venture 724, LLC
San Diego, CA · Founded 2024
SeedB2B
Seed$4.0M
MMTM SIX LLC
San Diego, CA · Founded 2023
SeedB2B
Series A$3.8M
Thorwear Inc
San Diego, CA · Founded 2019

Also known as Elevate Dynamics; co-founder Daniel Magy previously founded Citadel Defense Company, a counter-drone defense firm that was later acquired by Blue Halo.

Series AB2B
$3.8M
GetTheReferral.com, Inc.
San Diego, CA

GTR helps home service companies grow with referral software, branded apps, and automated rewards. Turn happy customers into your best lead source.

B2B
Seed$3.7M
Aervivo, Inc.
San Diego, CA · Founded 2020

Aervivo enables our Partners to provide community wide Gigabit managed WiFi, delighting the communities they serve and generating an outstanding 100%+ IRR, quickly.

SeedB2B
Series B$3.7M
Hotel Santa Clara LLC
San Diego, CA · Founded 2023
Series BB2B
Seed$3.5M
Crop Diagnostix, Inc.
San Diego, CA · Founded 2023

Crop Diagnostix uses plant RNA to detect asymptomatic crop stress before symptoms appear. Asymptomatic Agronomy for partners, retailers, and input providers.

SeedB2B
Seed$3.0M
AmbyTech Inc.
San Diego, CA · Founded 2024
SeedB2B
Seed$3.0M
Algenesis Corp
San Diego, CA

Soleic technology is the world's first fully biodegradable, high performance polyurethane material. Plant-based. Zero microplastics.

SeedB2B
Seed$2.8M
Self Inspection Inc.
San Diego, CA · Founded 2021

Self Inspection uses AI trained on 20M+ images to automate vehicle damage detection, condition reports, and CR scoring — built for dealers, fleets, rentals, and lenders.

SeedB2B
Series F$2.8M
Generative Platforms Inc.
San Diego, CA · Founded 2024
Series FB2B
Seed$2.3M
GroGuru, Inc.
San Diego, CA

Founded in 2014 by Patrick Henry, Farooq Anjum, and Jeff Campbell, the agtech soil-sensor company was acquired by Goanna Ag in August 2025.

SeedB2B
Series A$2.2M
Growthsayer, Inc.
San Diego, CA · Founded 2020

Growthsayer was founded by Phillip Geltman, a San Diego-based supply chain specialist who originally built the platform to optimize cannabis industry supply chains before expanding into broader retail demand planning.

Series AB2B
Seed$2.2M
Hauler Hero Inc.
San Diego, CA · Founded 2021

Hauler Hero is a waste management software solution that helps waste haulers improve their operations, increase efficiency, and reduce costs.

SeedB2B
Seed$2.1M
Biocanic, Inc.
San Diego, CA

Streamline your functional health business with Biocanic to get better better scale and outcomes for you and your clients.

SeedB2B
$2.0M
RCPS LLC
San Diego, CA

RCPS LLC does business as "Bulkhead," an energy drink brand based in Chula Vista, California.

B2B
Seed$1.9M
Exploration Technologies, Inc./DE
San Diego, CA · Founded 2023
SeedB2B
$1.5M
Assumable Technologies Inc.
San Diego, CA · Founded 2024

Operating as Assumable.io, it was co-founded by Ryan Carrillo and Louis Ortiz and drew national coverage (including the New York Times) for its marketplace matching buyers with homes carrying low-rate assumable mortgages.

B2B
Series B$1.5M
Algorithmic Objective Corp.
San Diego, CA · Founded 2019
Series BB2B
Seed$1.5M
Limar AI Inc.
San Diego, CA · Founded 2021
SeedB2B
Seed$1.4M
TPT GLOBAL TECH, INC.
San Diego, CA

TPT Global Tech is a technology holding company with an emphasis on Media Content, Medical Technology and Telecommunications.

SeedB2B
Seed$1.3M
Bench Talent Cloud, Inc.
San Diego, CA · Founded 2024

Recruitment CRM for full-time, seasonal, and contract talent. Outreach automation keeps relationships warm and makes rediscovery easy. Works with your ATS.

SeedB2B
Series A$1.2M
Yatiri Bio, Inc.
San Diego, CA · Founded 2021

San Diego cancer-drug-discovery company co-founded in 2020 by Pilgrim Jackson (13 years at Celgene) and Afshin Mahmoudi; backers include CONNECT San Diego.

Series AB2B
Seed$1.1M
Address Insite, Inc.
San Diego, CA · Founded 2023
SeedB2B
Series C$1.1M
W&CC SPV LLC
San Diego, CA · Founded 2025
Series CB2B
Pre-Seed$1.0M
Delta Trail Crane Services I LLC
San Diego, CA · Founded 2024

Founded by Austen Sybert in 2020 as an acquisition vehicle that bought and now operates Atlas Crane Service (a crane-services roll-up), rather than a from-scratch startup.

Pre-SeedB2B
Series A$1.0M
Shreenika Pioneering Inc.
San Diego, CA · Founded 2022
Series AB2B
$984K
Improv Beverages, Inc.
San Diego, CA · Founded 2022

For the ones who believe fun comes in all forms, there’s Improv Cocktails.Our full-flavored, premium non-alcoholic cocktails taste like the real deal, but without the booze. They’re ready to enjoy if you’re going dry, and ready to spike if you’re not.

B2B
Seed$955K
Lytng, LLC
San Diego, CA · Founded 2023
SeedB2B
$900K
DOUBLE GOLD HOLDINGS, INC.
San Diego, CA · Founded 2024

Led by CEO Jim Saxon, the Southern California holding company partnered with Spain's Mora-Figueroa Domecq, S.L. for tequila product management.

B2B
Series C$773K
Terafiber, LLC
San Diego, CA · Founded 2023

Terafiber was founded by Jim Hanley, a San Diego fiber-infrastructure entrepreneur who had previously founded Netly Fiber, another citywide fiber-network builder, before starting Terafiber in 2023.

Series CB2B
$770K
RallyCorp, Inc.
San Diego, CA

Mobile fundraising platform for nonprofits with compliant text messaging, Text-to-Give, and donor engagement. Trusted by 1,000+ organizations.

B2B
Series B$750K
GenseeAI Inc.
San Diego, CA · Founded 2024

GenseeAI, an AI agent infrastructure startup, was co-founded by UC San Diego professor Dr. Yiying Zhang and former Google tech lead Dr. Shengqi Zhu, and is backed by Two Small Fish Ventures.

Series BB2B
$735K
Southeast Idaho Storage 1, LLC
San Diego, CA · Founded 2025
B2B
Seed$725K
SmartProperty, Inc.
San Diego, CA

SmartProperty's Living Reserve Study gives HOA and condo boards real-time reserve fund tracking, capital planning, component inventory, and project management — replacing outdated static reserve studies with a dynamic, always-current platform.

SeedB2B
Series A$660K
Browser bets inc
San Diego, CA · Founded 2025
Series AB2B
Series B$650K
MHP Partners, Inc.
San Diego, CA · Founded 2025
Series BB2B
Series A$600K
Tiled, Inc.
San Diego, CA

Create engaging, interactive presentations effortlessly with Tiled. Enhance your storytelling and captivate your audience with dynamic, customizable content.

Series AB2B
Seed$568K
Scout Distribution AZ, LLC
San Diego, CA · Founded 2022
SeedB2B
Series B$555K
CHEFS LIFE CO, LLC
San Diego, CA · Founded 2020

Chefs Life was created in early 2021 by celebrity chef Brian Malarkey (a Top Chef alum and San Diego restaurateur).

Series BB2B
Seed$500K
Serinity, Inc
San Diego, CA · Founded 2026
SeedB2B
Pre-Seed$425K
International Boardriders League LLC
San Diego, CA · Founded 2022
Pre-SeedB2B
Series A$392K
Sided, Inc.
San Diego, CA

San Diego-based AI-powered polling and community-forum platform for digital publishers, founded by Scott Kaplan, a longtime ESPN 710 LA sports radio host.

Series AB2B
Seed$390K
MOI San Diego, LLC
San Diego, CA · Founded 2022

Discover the world's most extraordinary collection of perspective-changing rooms, mind-bending installations, and optical illusions.

SeedB2B
$350K
Angarak, Inc.
San Diego, CA · Founded 2019
B2B
Seed$318K
Perfect Herbal Blends, Inc.
San Diego, CA · Founded 2019
SeedB2B
Series C$310K
Brain Bioenergetics Inc.
San Diego, CA · Founded 2024
Series CB2B
Series B$300K
KAMIKI GLOBAL INC.
San Diego, CA

Blending a Japanese style whisky that harmonizes Japanese nature and artisanship

Series BB2B
Seed$300K
SuperMem Inc.
San Diego, CA · Founded 2019

San Diego-based SuperMem was founded by Yu Lu and has received funding including from the National Science Foundation and Techlink Ventures.

SeedB2B
Seed$275K
Swastham, Inc
San Diego, CA · Founded 2026

Founded by CEO Sucheta Godbole Deshpande, who in 2025/2026 appointed Theresa M. Brady to the company's board of directors as it builds out its AI-driven lifestyle health platform.

SeedB2B
Seed$260K
HAVYN LLC
San Diego, CA · Founded 2023

We believe that everyone - including those with sensitivities and allergies - should be able to enjoy fragrance. Our non-toxic fragrances are formulated to be free of all 82 EU fragrance allergens and top 9 food allergens, on top of being free from hormone disruptors and carcinogens.

SeedB2B
$250K
AurellaAI, Inc.
San Diego, CA · Founded 2026
B2B
Seed$250K
Healthy Crop, Inc.
San Diego, CA
SeedB2B
$200K
UFLO1, INC.
San Diego, CA · Founded 2024
B2B
Series B$178K
M&R Technology, Inc.
San Diego, CA · Founded 2022

M&R Technology, Inc. does business as The Infinity Shield and holds a U.S. patent (invented by Magid Fazel and colleagues) for garage-door safety sensors designed to protect pets and family members from accidental door strikes.

Series BB2B
Series A$170K
Site Bionics, Inc.
San Diego, CA · Founded 2023

Site Bionics unlocks AI for physical retail, enhancing loss prevention, optimizing store operations, and improving customer experience.

Series AB2B
Seed$150K
MLHere, Inc.
San Diego, CA · Founded 2020
SeedB2B
Series D$125K
Wallabi, Inc.
San Diego, CA · Founded 2023

Wallabi is your AI transformation partner. A strategy and implementation firm specializing in AI and data, built by leaders from Tableau, Salesforce, and Google.

Series DB2B
$119K
40acres & a BTC, Inc.
San Diego, CA · Founded 2025

Financial Freedom with Bitcoin. The digital assets partner for your business. OTC, Swaps, and Enterprise-Grade Solutions

B2B
Seed$100K
RPGMatch Inc.
San Diego, CA · Founded 2023

RPGMatch, a Los Angeles-based tabletop-gaming matchmaking startup, acquired the long-running gaming community site RPGnet in a 2024 merger, with RPGMatch owner Joaquin Lippincott becoming CEO of the combined company.

SeedB2B
Seed$75K
Cytodyme, Inc.
San Diego, CA · Founded 2024

AI-Enabled Quality and Regulatory Workflows

SeedB2B
$56K
Applied Learning Lab LLC
San Diego, CA · Founded 2025
B2B
$45K
Arc Interactive Inc. / DE
San Diego, CA · Founded 2025
B2B
$30K
Greenview Labs, Inc.
San Diego, CA · Founded 2026

According to its founder's LinkedIn profile, Greenview Labs is a golf technology startup founded by Harrison Fitz.

B2B
Seed$25K
Peak Summit Innovations
San Diego, CA · Founded 2025
SeedB2B
Seed$25K
Safu Sake Co
San Diego, CA · Founded 2020

Founded by Wharton MBA Paul Dohrenwend; its premium sake made its retail debut at a Costco in San Diego.

SeedB2B
Seed$10K
Craitor, Inc.
San Diego, CA

Craitor is a San Diego defense startup founded in 2019 by UC San Diego alum Eric Shnell (CEO) and Meher Akhil Birlangi; per Forbes, it has secured $3.3 million in U.S. government contracts.

SeedB2B
$6K
MAPLE FUNG MD INC
San Diego, CA · Founded 2025
B2B
$5K
Influsence, Inc.
San Diego, CA · Founded 2023

Influsence's Chief Advisor is Gil Eyal, founder of HYPR, the influencer-marketing platform he built and later sold (to Julius/JW) in 2020.

B2B
Rethoric
San Diego, CA · Founded 2021 · 4 employees

LinkedIn content consultancy and scheduling platform for busy founders

Y CombinatorB2B
Sourcify
San Diego, CA · Founded 2017 · 15 employees

Sourcify helps brands manufacture products in Asia.

Y CombinatorB2B
Integrated Reasoning
San Diego, CA · Founded 2022 · 1 employees

Faster processors for solving NP-complete problems

Y CombinatorB2B