B2B startups in Southern California
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
It's the largest category here by far, and one of the most varied — the best-funded names span Shield AI's defense-focused autonomy software in San Diego, Metropolis Technologies' AI-powered parking infrastructure in Santa Monica, and Impulse Space's in-space transportation services in El Segundo. What ties them together isn't a shared product category, just a shared buyer: another business, not a consumer.
Companies

Software platform for managing TikTok Shop operations for brands, agencies, and creators.
Pharma and medical-device compliance software plus licensing consulting.

Music-industry platform combining capital, distribution and rights-management technology, and A&R services for artists and labels in 100+ countries.


AI-native digital forensics and incident-response platform automating breach recovery for MSSPs, MSPs, and enterprises.

All-in-one restaurant platform offering a branded app, commission-free online ordering, loyalty, and marketing tools.

SoCal.Startups is a directory built for Southern California founders to find accelerators, investors, and events in one place, see what else is building in their city, and show off what they're building themselves.

Software platform managing enterprise IT device lifecycles — deployment, repair, retrieval, and retirement — for ITAD companies and MSPs.

AI platform unifying availability, pricing, and customer behavior data to help aftermarket auto-parts businesses optimize inventory and pricing.

Walmart-approved agency providing seller management — account setup, listing optimization, advertising, and analytics — for Walmart.com sellers.

Develops and operates AI-ready, build-to-suit, high-density data centers across North America and EMEA.
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Rents dedicated bare-metal GPU workstations, servers, and laptops with flat weekly or monthly pricing.

Smack Technologies is a frontier AI lab for national security that delivers decision dominance through proprietary, domain-specific models grounded in the physics of war and expert human priors.
Steno is a legal tech company offering court reporting services and a software platform to manage depositions, transcripts, and high-stakes litigation, aiming to make the process more efficient.
The future takes shape

Shield AI is a defense-tech company building the world's best AI pilots and next-generation aircraft.

Metropolis transforms the parking experience with a computer vision platform that enables checkout-free payment.

We provide efficient in-space mobility that moves payloads from low Earth orbit to any destination. Our vehicles deliver rapid, reliable access, reducing costs and timelines to make space operations feasible for commercial, government, and scientific missions.
This SEC filing entity shares Castelion's Torrance, CA address; founded in 2022 by three former SpaceX executives, it raised a $1 billion Series C led by Carlyle, JPMorgan Chase and Andreessen Horowitz.
Apex Technology provides value-driven, coordinated design, engineering and optimization services for single-family and multi-family construction projects across the nation.

TOCA offers indoor soccer training for all ages and skill levels. Kids classes, private training, adult pickup, leagues, and camps across North America.

ModRetro brings the best of the past to modern consumer electronics, for those who crave technology with a human soul.

CaskX offers whiskey cask investment and American bourbon barrel investment products to investors around the globe. Start your whiskey portfolio now.
Merkle Manufactory Inc. is a software company that contributes to the Farcaster protocol and works on clients.
Celero was founded by former Marvell senior executives Nariman Yousefi and Oscar Agazzi and raised $140 million for AI datacenter connectivity chips, including a reported $100 million investment from Google parent Alphabet.

Powering premium creator entertainment and delivering proven brand impact. Connect with YouTube's top creators through the leader in Creator TV.
This is the operating entity behind Angel City FC, the NWSL women's soccer club launched with a majority female-led celebrity ownership group including Natalie Portman, Serena Williams, and Eva Longoria.

MatX Inc. develops high-throughput chips designed for large language models (LLMs), focusing on achieving the best possible physical performance for frontier labs.

Focus on your art while we handle the complexities of talent management, including negotiations and long-term strategy.

Recovery Sports, LLC produces RECOVER 180™, an organic sports hydration drink that contains zero artificial dyes, vitamins, antioxidants, organic coconut water, and electrolytes.
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Led by CEO Maxx Mahdieh, the Beverly Hills beauty company disclosed a $110M SEC Form D offering in mid-2025, an unusually large filing for a company this size.
A Santa Monica company still operating in stealth mode (its actual business is undisclosed) that has nonetheless filed SEC Form D notices for roughly $150M in offerings since 2023.

Acquisition.com provides workshops, courses, books, and media to help businesses scale, leveraging the experience of a team that has scaled a portfolio to over $250m+ in annual revenue.
According to Crunchbase, it was founded by actor Darius McCrary, best known for playing Eddie Winslow on the sitcom "Family Matters."

Mach Industries is building faster, smarter defense infrastructure for the modern era.

DigitalBridge is a leading global alternative asset manager dedicated to investing in next-generation digital infrastructure and GenerativeAI

Maxdao provides products and services for building future infrastructure, specializing in mounting brackets, cable clamps, adapters, hangers, and other installation components for various industries like communications and renewable energy.

PatientFi, Inc. provides monthly payment plans to help patients break cost barriers for procedures in areas such as plastic surgery, medspa & dermatology, fertility, hair restoration, audiology, cosmetic dental, and vision.
Advanced material solutions—from AI-driven design to agile U.S. manufacturing—for defense, aerospace, & high-performance applications
Zen Beverage (maker of ZenWTR) was founded by Lance Collins, the serial beverage entrepreneur who previously created BodyArmor and sold Fuze Beverage to Coca-Cola for $250M.
Vertimass seeks to develop and widely license breakthrough technologies that convert renewable ethanol into hydrocarbons to expand the use of sustainable transportation fuels.

Bright Peak Therapeutics is a company that uses its protein engineering capabilities to create multifunctional precision immunotherapies for the treatment of cancer.

Bloom Nutrition provides health and wellness supplements for women, with high quality ingredients to support energy, gut health and hormone balance. Shop our greens, beauty and fitness supplements.

AstroForge is a commercial space startup focused on asteroid mining and the extraction of platinum group metals and other critical minerals. Explore our deep space missions and discover how we’re shaping the future of space resources and off-world mining.

Firestorm Labs - Democratize the fight with radically-affordable, mission-adaptable power for air, land, and sea.

FDA-cleared dental AI that detects 37% more disease. Join 29,000+ dental practices using Pearl's dental AI software. Book a demo.

Outpace AI-driven attacks. Unify Digital Risk Protection, Human Risk Management, and Email Security to stop digital threats before they scale, empower your teams to lead your defense, and scale your SOC with agentic AI.