B2B startups in Southern California

Capra Projects specializes in creating frameless glass, architectural steel, and aluminum solutions, including balustrades, showers, doors, and staircase design and construction.

Does business as ChipAgents, an agentic AI chip-design platform founded by CEO William Wang; has raised $134M in funding from investors including Bessemer Venture Partners and Matter Venture Partners.

ProrataAI, Inc. builds AI-powered search, advertising, and attribution solutions that respect content creators and publishers by ensuring transparent crediting and equitable value sharing.

Supplying Demand, Inc. provides quality HVAC, appliance, and repair parts for professionals and homeowners.

Legal name of Flip, the TikTok-style social shopping app headquartered in El Segundo, CA; the company raised $144M and reached a $1B valuation before shutting down in August 2025.

Kudos® is the recognition and rewards platform designed to fit your unique workplace culture.

Brasada Ranch is a family-friendly resort located just outside of Bend, Oregon that features luxurious accommodations, championship golf, world-class dining and amenities, and endless recreation throughout Central Oregon.

1 Supercompany, 7 Frontier Labs Building an Everything Supercompany for Humanity

HiveWatch provides a platform that unifies physical security systems into one AI-powered command center to help security teams prioritize incidents and automate responses.

Electrochemical Additive Manufacturing Mass Production of Next Generation Components High-Resolution Metal 3D Printing at Scale Electrochemical Additive Manufacturing (ECAM) is... Read More

Big Shot Pictures is a next-generation studio building global franchises, founded by Brian Robbins.

Praesidium applies an owner-oriented, private equity approach to investing in the public markets. Praesidium manages long-term capital for a select group of institutional investors.

TITAN CONTENT is a K-pop entertainment company based in the United States. We create global & innovative K-pop artists and content.

Make smarter real estate decisions and close more deals with Placer.ai's location intelligence and foot traffic insights.

Laxmi will help people with diabetes stay in range more often, supporting better day-to-day control and long-term health through industry-first dermal continuous glucose monitoring.

Tide Rock is a growth platform for B2B companies that acquires founder-run businesses using an unlevered buyout model to grow their legacy.

Lose weight, get fit and feel great anytime, anywhere with free on-demand fitness classes, personalized workout plans and guided meditations.

Virtualitics is an AI solutions company that transforms data into impactful action with AI readiness applications for defense, government, and enterprise.

Epsilyte manufactures expandable polystyrene EPS materials for insulation, protective packaging, cold chain, foodservice, and molded applications.

Metro Coffee is an Onsite Beverage Service provider located in the Metro Atlanta area

Deep 6 AI, founded in 2013 by Brian Dolan and Wout Brusselaers with backing from Point72 Ventures and the Cedars-Sinai Accelerator, was acquired by Tempus AI (Nasdaq: TEM) in March 2025.

Counterpart is the first Agentic Insurance™ system specializing in management and professional liability insurance.

Affinity Biosensors’ LifeScale platform delivers rapid, high-throughput phenotypic antimicrobial susceptibility testing in under four hours, empowering clinical labs to make timely antibiotic decisions and combat drug-resistant infections.

Robotics Startup for Space Development

Movandi Corp develops next-generation mmWave solutions that power both terrestrial and non-terrestrial communications, advancing 5G, fixed wireless, and satellite networks worldwide.

ABL Space Systems is a company based in El Segundo, California, focused on launch vehicle and launch systems technology development.

Global Spirits is one of the world's leaders in alcohol production.

Transcend is the only real-time data governance and decision layer that answers “Can I use this data?” to unblock AI, agentic, and first-party data initiatives.

Electric Solidus, Inc. is the legal name behind Swan Bitcoin, founded by well-known Bitcoin investor Cory Klippsten along with Brady Swenson and Yan Pritzker, headquartered in the LA area (Calabasas).

Qardio is making heart health easier for everyone. Improve your health by tracking your blood pressure, ECG & heart rate, weight, body composition and more.

unlimited AI conversations, translation, and voice recordings — all in your $199 AI-native device rabbit r1, plus a chance to explore cutting-edge agents.

California Naturals, Inc. sells clean, natural, and effective daily essentials for hair, body, kids, and men, available in various scents and for different needs.

Matter Intelligence is pioneering a new ultraspectral vision ecosystem that sees molecular chemistry, unlocking superintelligent vision for the physical world.

Gallant offers ready-to-use stem cell therapies that help pets heal from within, restoring vitality and supporting longer, healthier lives.

Salted Inc. is a platform that builds national, digital-first restaurant brands with clean, craveable food designed for a new generation.

John Paul DeJoria, co-founder of Patrón Tequila and Paul Mitchell hair-care, joined the company as an advisor and investor.

Brain Corp is an autonomous technology company powering the most proven robots and AI, helping organizations create more productive and intelligent operations.

Pave LLC provides nationwide commercial parking lot management services including asphalt and concrete maintenance, crack sealing, sealcoating, and striping.

Sol-ti sells organic living beverages, including SuperShot, SuperAde, and SuperStix products, which are glass bottled, cold pressed, and made in the USA.

Co-founded by CEO Nicole Clark in 2017; the legal analytics platform raised a $15 million Series B in 2023.

Price with precision. Negotiate with confidence. Turquoise is the platform 300+ healthcare organizations use to make sense of rates, contracts, and compliance.

Operates as Seasats; CEO and co-founder Mike Flanigan launched the San Diego autonomous-vessel maker in 2020, and it closed a $20 million Series A backed by Philip Bilden.

Feel free, feel good. feel free tonics and capsules feature noble kava root & other functional botanicals from around the world. Thoughtfully crafted to deliver a mood lift, a boost of energy, and a focus enhancement.

The Encinitas-based clinical-stage biotech was acquired by Eli Lilly for $1.2 billion in cash, after IPOing on Nasdaq (VTYX) in 2021.

GATC Health is a tech-bio company that uses proprietary AI to accelerate and de-risk the discovery and development of safer and more effective drugs for biopharma companies and investors.

Founded by Jonathan Yaney and backed by Google Ventures, Airbus Ventures and Kleiner Perkins, the company builds a kinetic (spinning) launch system to hurl satellites toward orbit instead of using rocket boosters for the first stage.

Enhance, extend or replace your legacy GTM software with affordable enterprise-grade AI-native trade and tariff management software from KYG Trade.

Mapped turns any building's systems, sensors, and devices into a structured, real-time world model — the data foundation AI agents and applications need to understand and act on the physical world.