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SANTA BARBARA

B2B

B2B startups in Santa Barbara. Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.

28
companies
$164.2M
total raised
Series A$48.5M
AFFINITY BIOSENSORS LLC
Santa Barbara, CA

Affinity Biosensors’ LifeScale platform delivers rapid, high-throughput phenotypic antimicrobial susceptibility testing in under four hours, empowering clinical labs to make timely antibiotic decisions and combat drug-resistant infections.

Series AB2B
$25.0M
Mesa Residential Co LLC
Santa Barbara, CA · Founded 2025
B2B
$13.2M
Painted Cave, Inc.
Santa Barbara, CA · Founded 2021

Butterflies are free to fly

B2B
Seed$8.9M
Cognixion Corp
Santa Barbara, CA · Founded 2021

Cognixion develops accessible, non-invasive brain-computer interfaces combining neuroscience, AI, and spatial computing.

SeedB2B
Series A$7.6M
H2 Clipper, Inc.
Santa Barbara, CA · Founded 2022

The infrastructure for the distribution of liquid hydrogen.

Series AB2B
Series A$7.5M
DIMER INSTRUMENTS, INC.
Santa Barbara, CA · Founded 2023
Series AB2B
Series A$7.3M
bioProtonics, Inc.
Santa Barbara, CA · Founded 2018

BioProtonics is a pioneering company focused on advancing diagnostic imaging through its Magnetic Resonance Histopathology (MRH) technology. MRH offers a non-invasive, high-resolution method for analyzing tissue microarchitecture during routine MRI scans. MRH

Series AB2B
Series A$7.1M
Live Data Technologies, Inc.
Santa Barbara, CA · Founded 2019

Live Data Technologies, led by CEO J. Scott Hamilton, has raised $13.3 million from investors including Entrada Ventures and Tappan Hill Ventures.

Series AB2B
Series D$6.7M
Learning Explorer, Inc.
Santa Barbara, CA · Founded 2021

Learning Explorer, founded by Jim Hurley in 1999, has raised about $18.1M in total funding, including a recent $2.5M investment from Founderpath.

Series DB2B
Seed$6.2M
Musubi Inc.
Santa Barbara, CA · Founded 2023

We are wholesalers in Japan who import / export Japanese-made products such as everyday items, cosmetics, snacks and food at wholesale prices.We also offer proxy marketing for Japanese companies as well as wholesalers.

SeedB2B
Seed$5.6M
Cliq Products Inc.
Santa Barbara, CA · Founded 2020

CLIQ makes the world’s most portable chairs—ultra-compact, quick to set up, and built for everyday adventure. Whether you’re camping, tailgating, or relaxing at the beach, CLIQ chairs offer comfort, durability, and convenience in a sleek, travel-ready design.

SeedB2B
Seed$3.0M
Shoonya Digital, Inc.
Santa Barbara, CA · Founded 2019

Language learning for kids is easy with Shoonya. Designed to be the best language software for kids, we have many languages to choose from.

SeedB2B
Seed$2.8M
SBMAR25, LLC
Santa Barbara, CA · Founded 2025
SeedB2B
$2.7M
Blue-OCN-Capital, Holdings, LLC
Santa Barbara, CA · Founded 2022

BESPOKE SOLUTIONS FOR A DYNAMIC M&A ENVIRONMENT.

B2B
Seed$2.1M
Veles
Santa Barbara, CA · Founded 2024 · 5 employees

CPQ for humans and agents

Y CombinatorSeedB2B
$2.0M
Adaya AI, Inc.
Santa Barbara, CA · Founded 2022

Adaya AI was co-founded by Alicia Evergreen and Justin Evergreen and has raised roughly $2M in seed funding.

B2B
Seed$1.8M
9ZERO INC.
Santa Barbara, CA · Founded 2023

Join 9Zero, a climate innovation hub for founders, investors, scientists, and innovators. Explore memberships, events, and workspace in SF and Seattle.

SeedB2B
Seed$1.4M
Shelter DP, LLC
Santa Barbara, CA · Founded 2025

Shelter Products Inc. specializes in delivering high-quality building materials for large-scale construction projects nationwide. Discover how we can help you.

SeedB2B
Seed$1.3M
KR Investment Partners Select LLC
Santa Barbara, CA · Founded 2024
SeedB2B
Seed$1.3M
Benefact(or), Inc.
Santa Barbara, CA · Founded 2021

Operating as "Beni," this company was founded in 2021 by Sarah Pinner and Celine Mol in Santa Barbara, has raised over $5 million in venture funding, and is a Google for Startups alum.

SeedB2B
Seed$650K
Storygize Inc.
Santa Barbara, CA

Storygize was founded in 2015 by David Osman and has raised roughly $10 million in total funding for its programmatic advertising platform, headquartered in Santa Barbara.

SeedB2B
Seed$500K
Expond Inc.
Santa Barbara, CA · Founded 2021

Explore private in-person and group experiences: Yoga, personal training, kayaking, hiking, surfing, meditation and so much more in Santa Barbara, California!

SeedB2B
Seed$450K
Remaker Labs, Inc.
Santa Barbara, CA

Remaker Labs, co-founded by Sky Gilbar and David Silverander in Santa Barbara, raised $1.2M from over 15,000 Kickstarter backers in 70 countries for its 'Hitch' cup-and-bottle product, according to Forbes.

SeedB2B
Series A$430K
SkillBench, Inc.
Santa Barbara, CA · Founded 2024

AI-enabled productivity and skill optimization for firms using Generative AI

Series AB2B
Series C$200K
Glimmer Wish LLC
Santa Barbara, CA · Founded 2026

Glimmer Wish is Clean & Fun Beauty. Glimmer Wish was created to make self care, hair care, and beauty products that you can trust to be safe, free of harsh chemicals, and as cute as can be.

Series CB2B
$50K
Reel Fit, Inc.
Santa Barbara, CA · Founded 2024
B2B
$30K
Calculated Development LLC
Santa Barbara, CA · Founded 2020

Calculated Development LLC was formed to turn author Nova McBee's bestselling "Calculated" novel series into a film franchise, now in development with One Door Studios and Apelles Entertainment.

B2B
$5K
Skin Safeguard Inc
Santa Barbara, CA · Founded 2024
B2B