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B2B startups in Southern California

Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.

It's the largest category here by far, and one of the most varied — the best-funded names span Shield AI's defense-focused autonomy software in San Diego, Metropolis Technologies' AI-powered parking infrastructure in Santa Monica, and Impulse Space's in-space transportation services in El Segundo. What ties them together isn't a shared product category, just a shared buyer: another business, not a consumer.

1030
companies
$20.56B
total raised
62
cities

Companies

Proper Voltage, Inc. hero photo
Series A$25.0M
Proper Voltage, Inc.
Carlsbad, CA

Proper Voltage is the digital bridge that seamlessly links power and product, opening up access to more choices and possibilities.

Series AB2B
$25.0M
Mesa Residential Co LLC
Santa Barbara, CA · Founded 2025

Mesa Residential partners with market-leading property managers to grow for decades as a multigenerational platform with over 50 years of history building exceptional growth companies.

B2B
Catalex Network Partners LLC hero photo
$25.0M
Catalex Network Partners LLC
Newport Beach, CA · Founded 2025

Catalex Network is a private capital-backed partner for elite boutique insurance defense law firms — back office, technology, and growth resources without giving up your culture.

B2B
Community.com, Inc. hero photo
Series D$25.0M
Community.com, Inc.
Santa Monica, CA · ~11-50 employees

Personalized, two-way SMS, WhatsApp, Apple Messages, RCS, and more. No algorithms. No noise. Just your Community.

Series DB2B
Arvo Partners, LLC hero photo
$24.9M
Arvo Partners, LLC
San Diego, CA · Founded 2022

Avaamme mahdollisuudet ja takaamme sinulle paremman kasvun: Arvo Partners, täyden palvelun digitaalinen markkinointitoimisto ja tuleva strateginen kumppanisi.

B2B
$24.4M
Muse Organic, LLC
Long Beach, CA · Founded 2020

Muse Organic (maker of MyMuse hydration drinks) was co-founded by Linda Collins, who also co-founded the bottled water brand ZENWTR.

B2B
Charlie Financial Inc. hero photo
Series A$23.5M
Charlie Financial Inc.
Los Angeles, CA · Founded 2021

Access to Social Security 3-5 days early.

Series AB2B
Quintessent Inc. hero photo
Series A$23.2M
Quintessent Inc.
Goleta, CA · Founded 2019

Quintessent is developing optical connectivity solutions to scale computing and Artificial Intelligence (A.I.).

Series AB2B
$23.1M
New Nixon Holdings, Inc.
Carlsbad, CA

The entity behind Nixon, the watch and accessories brand founded in 1997 by Andy Laats and Chad DiNenna, which is now backed by private equity firm Trilantic Capital Management.

B2B
GrowthBook, Inc. hero photo
Series A$22.6M
GrowthBook, Inc.
Anaheim, CA · Founded 2020

The 1st warehouse-native platform for experimentation, feature flags, and product analytics. Open source and fully transparent. Trusted by 3,000+ companies.

Series AB2B
Series A$22.4M
ViaVia Corp
West Hollywood, CA · Founded 2021

Welcome to VIAVIA! Redefining the fashion experience for a new generation // Enjoy free shipping and returns on all orders // New Designers and products dropping daily

Series AB2B
Uplifting Results Labs, Inc. hero photo
Series A$22.0M
Uplifting Results Labs, Inc.
Culver City, CA

Uplifting Results Labs, Inc. provides AI 3D motion capture technology for sports performance, sports medicine, and sports media, utilizing smartphone technology for biomechanical analysis.

Series AB2B
AgentAI Holdings, Inc. hero photo
Series B$22.0M
AgentAI Holdings, Inc.
Woodland Hills, CA · Founded 2025

Medical billing and revenue cycle management where AI agents carry every claim and expert billers fight the hard dollars. Free scan of your last 90 days.

Series BB2B
Innova Vascular, Inc. hero photo
Series A$21.9M
Innova Vascular, Inc.
Irvine, CA

Innova is engaged in developing innovative medical devices for treating vascular disease using a minimally invasive approach. Contact us.

Series AB2B
Series A$21.4M
Caramel, Inc.
Encino, CA · Founded 2021 · ~11-50 employees

Caramel is the safe & easy way to complete any private used car sale. Compatible with any car for sale by owner, Caramel does the DMV work & more for free.

Series AB2B
Kinetic Automation Inc. hero photo
Series B$21.0M
Kinetic Automation Inc.
Santa Ana, CA · Founded 2021

Kinetic Automation provides solutions for modern vehicle repair, including automated imaging for collision estimates with Kinetic Vision and digital collision repair services in Kinetic Hubs.

Series BB2B
Series B$21.0M
SYDNEXIS, INC.
Del Mar, CA · ~11-50 employees

Sydnexis focuses on advancing innovation to treat pediatric progressive myopia, which is the leading cause of vision loss in children, by addressing a critical gap in care.

Series BB2B
Series A$20.5M
Immortal Inc.
Los Angeles, CA · Founded 2025

Immortals Inc is a game and hobby store in Northeast Ohio that offers collectible card games, role-playing adventures, miniature battles, and classic board games, along with dedicated play spaces and events.

Series AB2B
$20.0M
Space & Time Labs, Inc.
San Clemente, CA · Founded 2022
B2B
$20.0M
Anthropocene V, LLC
Studio City, CA · Founded 2025
B2B
$20.0M
PDS Equities, LLC
Irvine, CA · Founded 2021
B2B
NanoImaging Services, Inc. hero photo
Seed$19.7M
NanoImaging Services, Inc.
San Diego, CA

NIS, a US based CRO, provides cryo-EM services to accelerate drug discovery, with structural biology, nanoparticle characterization, and GMP compliant imaging.

SeedB2B
$19.6M
EMBER TECHNOLOGIES, INC.
Westlake Village, CA
B2B
ALT Sports Data, Inc. hero photo
Seed$19.2M
ALT Sports Data, Inc.
Carlsbad, CA · Founded 2021

Unlock Engagement, New Fans & Revenue Through Sports Betting

SeedB2B
Series A$18.9M
Novo Space, Co.
Venice, CA · Founded 2019

Novo Space, Co. offers a full ecosystem of products to simplify the development process of complex space systems, including tailored subsystems, electronic boards, and FPGA IP Cores.

Series AB2B
Infracost Inc hero photo
Series A$18.8M
Infracost Inc
San Diego, CA · Founded 2021

FinOps governance for platform teams. Prevent cloud waste and budget overruns before every deploy.

Series AB2B
$18.6M
Hello Cake, Inc.
North Hollywood, CA
B2B
Series B$18.5M
Buffalo Market, Inc.
Los Angeles, CA · Founded 2019
Series BB2B
JINX, INC. hero photo
Series B$17.8M
JINX, INC.
Los Angeles, CA · Founded 2019 · ~51-200 employees

JINX, INC. offers premium dog and cat food, toppers, and treats crafted with high-quality proteins, superfoods, and probiotics.

Series BB2B
Equatic Inc. hero photo
Series A$17.8M
Equatic Inc.
Torrance, CA · Founded 2021 · ~51-200 employees

Equatic has developed an electrolytic process for atmospheric carbon dioxide removal that leverages the size and scale of the oceans, stabilizing carbon dioxide and producing hydrogen as a co-product.

Series AB2B
Passes, Inc. hero photo
Series A$17.6M
Passes, Inc.
Los Angeles, CA · Founded 2022 · ~11-50 employees

Passes allows creators to monetize their content and build direct relationships with their audience through subscriptions, messaging, and exclusive content.

Series AB2B
Sift Stack, Inc. hero photo
Series B$17.5M
Sift Stack, Inc.
El Segundo, CA · Founded 2022

Sift is the unified observability platform for mission-critical hardware—ingest, store, and analyze telemetry at scale across aerospace, defense, and robotics.

Series BB2B
BlueQubit Inc. hero photo
Seed$17.2M
BlueQubit Inc.
Los Angeles, CA · Founded 2022

Unlock quantum power with BlueQubit's quantum computing software! Seamlessly access and utilize quantum computers for groundbreaking advancements.

SeedB2B
AnySignal, Inc. hero photo
Series A$17.0M
AnySignal, Inc.
El Segundo, CA · Founded 2022

The integrated platform for the electromagnetic spectrum. One platform for RF design, production, and network operations.

Series AB2B
Series B$16.7M
Fictions, Inc.
Los Angeles, CA · Founded 2024

Fictions is a game developer and publisher established in 2025. Current titles include LEGO Party and Beast of Reincarnation.

Series BB2B
Nuon Inc. hero photo
Series A$16.6M
Nuon Inc.
Beverly Hills, CA · ~11-50 employees

Nuon Inc. provides continuous delivery solutions that enable software vendors to deploy applications into their customers' clouds, supporting use cases like data sovereignty and security.

Series AB2B
Series A$16.5M
Systm Foods Inc.
Newport Beach, CA · Founded 2022

SYSTM Foods is a company focused on strategically acquiring and nurturing a portfolio of cold chain beverage brands that offer better-for-you functional beverages, including organic coffee, plant-based protein, and low/no sugar gut health options.

Series AB2B
Gamefam, Inc. hero photo
Series A$16.5M
Gamefam, Inc.
Los Angeles, CA · Founded 2019

Gamefam creates immersive gaming experiences for brands on Roblox and Fortnite, engaging Gen Z & Alpha audiences through innovative campaigns and full-scale amplification programs.

Series AB2B
Accrual, Inc. hero photo
Series A$16.4M
Accrual, Inc.
Beverly Hills, CA · Founded 2024

Accrual transforms accounting firms with AI. Automate tax returns, streamline client data collection, and scale your practice with intelligent workflows.

Series AB2B
Series B$16.4M
Mixed-Signal Devices Inc.
Irvine, CA

Mixed-Signal Devices Inc. delivers multi-gigahertz digital timing solutions with ultra-low jitter, stability, and programmability for AI infrastructure, 5G networks, and high-performance automotive platforms.

Series BB2B
TAD HEALTH INC. hero photo
Series A$16.2M
TAD HEALTH INC.
Newport Beach, CA · Founded 2021

TadHealth is the leading school-based EHR platform designed for K‑12 schools, empowering mental health professionals with intuitive tools to manage care, streamline operations, and improve student outcomes.

Series AB2B
EggCo, Inc. hero photo
Seed$15.8M
EggCo, Inc.
Los Angeles, CA · Founded 2021 · ~11-50 employees

EggCo, Inc., operating as Sunnyside Egg Co., produces eggs from hens raised outdoors in mobile coops on fresh pastures, supplemented with certified organic feed without corn, soy, or flax, using regenerative practices.

SeedB2B
$15.8M
Rosten Capital Investments LLC
Newport Beach, CA · Founded 2021
B2B
Verve Cloud, Inc. hero photo
Series B$15.8M
Verve Cloud, Inc.
San Diego, CA

An integrated communications platform using cloud-hosted phone, chat, contact center and analytics to meet the challenges of today’s business.

Series BB2B
$15.7M
Radical Group Inc.
Venice, CA · ~11-50 employees

Radical Group Inc. helps businesses unlock their full potential through integrated solutions in Data, AI, Digital Design, and Training.

B2B
Huupe Inc. hero photo
Series A$15.6M
Huupe Inc.
Irvine, CA · Founded 2020

huupe brings you the world’s first smart basketball hoop, providing NBA level workouts, on-demand training, live coaching, data tracking and more.

Series AB2B
PM Technologies Corp hero photo
Series B$15.6M
PM Technologies Corp
Beverly Hills, CA · Founded 2022

PM Technologies Corp provides generator sales, installation, service, and maintenance for residential, commercial, and industrial customers, focusing on emergency power solutions.

Series BB2B
FOURSQUARE FINANCIAL SOLUTIONS LOAN FUND, INC. hero photo
$15.1M
FOURSQUARE FINANCIAL SOLUTIONS LOAN FUND, INC.
Los Angeles, CA

Welcome to The Foursquare Church. Discover how Foursquare supports local churches and raises up future leaders.

B2B
SWARM Engineering, Inc. hero photo
Series A$15.0M
SWARM Engineering, Inc.
Irvine, CA

AI-powered optimization platform that uses domain-trained intelligent agents built for operations teams.

Series AB2B
Series B$15.0M
Stone Engineering Equity Group, LLC
Carlsbad, CA · Founded 2025

This Carlsbad, CA private-equity vehicle for engineered stone manufacturing is run by managing member Oren Klaff, the investor and author best known for the bestselling sales book "Pitch Anything."

Series BB2B
$15.0M
HARRISON ROSS FUNERAL HOME INC
Los Angeles, CA

Operating as Harrison-Ross Mortuary in LA, this family-owned funeral home has served the community since 1948 and is now led by its third-generation leader, Chip Smith.

B2B
$15.0M
Cyber Wave X LLC
Los Angeles, CA · Founded 2025

Physical AI infrastructure from code to real world. Abstract with Digital Twins, plug in AI, and ship to production.

B2B
Series A$15.0M
LEGALMATION, INC.
Los Angeles, CA · ~11-50 employees
Series AB2B
North Beam, Inc. hero photo
Series A$15.0M
North Beam, Inc.
El Segundo, CA

Multi-touch attribution and media mix modeling for profitable growth, powered by industry-leading machine learning models. Discover how Northbeam can transform your marketing.

Series AB2B
Goldfinch Technology Co hero photo
Series B$15.0M
Goldfinch Technology Co
Covina, CA · Founded 2021

Unprecedented onchain exposure to the world's leading institutional grade private credit managers, including Ares, Apollo, and more.

Series BB2B
Seed$14.6M
Modyfi, Inc.
Los Angeles, CA · Founded 2021

Modyfi delivers integrative psychiatric care via telehealth — whole-person, insurance-based treatment connecting mind, body, and lifestyle.

SeedB2B
Soapbox Holdings, Inc. hero photo
$14.6M
Soapbox Holdings, Inc.
Santa Monica, CA · Founded 2021

Soapbox provides a platform that centralizes, simplifies, and orchestrates order management, inventory management, and shipping management across the entire supply chain.

B2B
Needed PBC hero photo
Seed$14.6M
Needed PBC
Los Angeles, CA

Science-backed fertility, prenatal, postpartum, perimenopause, and women's health supplements. Trusted by 20,000+ practitioners and experts. Shop Needed.

SeedB2B
Series A$14.5M
JS-WR JV, INC.
San Diego, CA · Founded 2025

JS-WR JV, Inc. does business as Willie's Remedy+, the CBD/THC beverage and wellness product line created by musician Willie Nelson.

Series AB2B
Arrow App, LLC hero photo
Seed$14.4M
Arrow App, LLC
Manhattan Beach, CA · Founded 2023

Arrow turns the heavy equipment industry

SeedB2B