B2B startups in Huntington Beach. Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.

Mach Industries is building faster, smarter defense infrastructure for the modern era.

AstroForge is a commercial space startup focused on asteroid mining and the extraction of platinum group metals and other critical minerals. Explore our deep space missions and discover how we’re shaping the future of space resources and off-world mining.

Replacing Hearts. Restoring Lives. HEART FAILURE Heart failure is a global epidemic affecting at least 26 million people worldwide, 6.2 million adults in the U.S., and is increasing in prevalence. Heart transplantations are reserved for those with severe heart failure and
Boardriders is the ultimate destination for action sports & lifestyle. We connect a global community of dreamers through authentic experiences & the most legendary brands.

Authentically bringing the flavors of Mexico to the canned cocktail and beer industry through a lineup of sessionable, premium tequila cocktails and crafted beers.
Operating as SCATS Gymnastics in Huntington Beach, the nonprofit club has produced 14 U.S. Olympic Team members and over 70 U.S. National Team members.

Founded by aerospace veterans Ben Schleuniger and Ross Doherty (formerly of NASA, SpaceX, and Relativity Space) and backed through Y Combinator's Winter 2025 batch; investors include Batch Ventures, DTX Ventures, and Mercury co-founder Immad Akhund.
Co-founded in 2023 by JB Jakubek and based in Huntington Beach, building a social, gamified sports collectibles and rewards platform.