B2B
68 b2b startups based in Irvine, $724.7M raised total, led by ModRetro, Inc. ($164.3M raised). See what B2B means more broadly on the B2B industry page.
The breakdown
62 of 68 companies have disclosed funding, $724.7M combined, 14 at Series A stage, making up 29% of the 231 Irvine startups on file across every industry, founding dates span 2018-2026.
Companies

ModRetro brings the best of the past to modern consumer electronics, for those who crave technology with a human soul.

PatientFi, Inc. provides monthly payment plans to help patients break cost barriers for procedures in areas such as plastic surgery, medspa & dermatology, fertility, hair restoration, audiology, cosmetic dental, and vision.
Vertimass seeks to develop and widely license breakthrough technologies that convert renewable ethanol into hydrocarbons to expand the use of sustainable transportation fuels.
Movandi Corp develops next-generation mmWave solutions that power both terrestrial and non-terrestrial communications, advancing 5G, fixed wireless, and satellite networks worldwide.
GATC Health is a tech-bio company that uses proprietary AI to accelerate and de-risk the discovery and development of safer and more effective drugs for biopharma companies and investors.
Innova is engaged in developing innovative medical devices for treating vascular disease using a minimally invasive approach. Contact us.
Mixed-Signal Devices Inc. delivers multi-gigahertz digital timing solutions with ultra-low jitter, stability, and programmability for AI infrastructure, 5G networks, and high-performance automotive platforms.

huupe brings you the world’s first smart basketball hoop, providing NBA level workouts, on-demand training, live coaching, data tracking and more.

AI-powered optimization platform that uses domain-trained intelligent agents built for operations teams.
Theraheart Inc. is a medical device manufacturer dedicated to providing innovative, minimally invasive solutions aimed at improving the lives of Heart Failure patients.

Accelerating humanity’s galactic destiny
Orbee is the automotive data platform that unifies every customer signal so dealerships can activate smarter audiences, run better campaigns, and close more deals.

The collective brain for high-velocity teams. Join waitlist: highlightai.com

Permissionless Labs is an AI lab providing high-throughput inference, durable model storage, and custom fine-tuning — frontier infrastructure you can access without gatekeepers or lock-in.
CU Direct Corp, founded in 1994 and now branded as Origence, is a credit union service organization (CUSO) collectively owned by 124 credit union shareholders rather than by venture investors.
Autopilot was built by the team behind the viral 'Pelosi Tracker' and lets users copy politicians' and top traders' stock trades; co-founder Brian Schardt has said the app manages roughly $1.8B in tracked assets.
Petalfast Inc. equips cannabis brands for sustainable success through sales and distribution, integrated sales planning, and infrastructure.

We partner with global industry leaders to craft and deliver groundbreaking consumer electronics and connected solutions.

Comprehensive compliance platform for broker-dealers and fintechs. Automate CAT/CAIS reporting, best execution analysis, trade surveillance, corporate actions, and data reconciliation.

Official website of Cochl
Co-founded and led by CEO Isaac Oswalt; it is a private-equity roll-up platform that acquires and consolidates short-term rental operators while letting the original operators retain equity.
ATEN provides solutions across various markets and applications, offering products like KVM switches, professional audio/video equipment, consumer electronics, and USB solutions.
Professional-Grade Sawhorses, Tool Pouches and Knee Pads for work by ToughBuilt. Strictly for construction workers and electricians who need the best for the job!

Turn your bread into dough. The Simply Bread Oven and app help bakers at every stage bake more, sell more, and grow a thriving micro-bakery.

SocialCrowd automatically tracks employee progress towards goals, reminds them of the work they have left, and rewards them instantly – so you can save time and stay focused!

Toro Neurovascular develops advanced stroke devices, specifically catheter technology, for the treatment of ischemic stroke.
AgBlox is an AI platform that predicts agricultural commodity prices.

Telesair, Inc. is a non-invasive ventilation manufacturer. We enable respiratory care in any setting through high-flow oxygen generation and portability.

Experience Viseon's Advanced Digital Visualization CRANIALSPINALExperience Viseon's

Empowering Indie Artists to Connect, Grow, and Earn - OpenWav
ZUUM Transportation is a logistics technology company that develops a comprehensive logistics platform including ZUUM Automated Broker for freight brokers to digitize operations and ZUUM BEYOND TMS for shippers.

Bedrock Servicing provides a hybrid operating model for private credit lenders. We combine institutional-grade loan servicing with proprietary technology to automate complex asset management, ensure audit-readiness, and eliminate administrative friction.

AI-powered travel technology SaaS platform offering end-to-end solutions for Corporates, B2B, and B2C.
XOStem Biosciences' listed principals include UC Irvine professor Jonathan Lakey, who co-developed the Edmonton Protocol, the landmark pancreatic islet cell transplantation procedure for treating type 1 diabetes.
Food Safety Systems LLC provides food safety and sanitation resources, compliance, education & training, verification, and technology services primarily for the food services industry in Southern California.

A unified solution to measure risk, reduce downtime, and strengthen insurance outcomes.
Thumb Technologies, an Irvine, CA conversational-analytics startup, was co-founded by Jae Chung (previously at Amazon and Autodesk) and Daniel Kopeinigg.

Bluon provides indispensable technical data and support to the HVAC professional industry via our proprietary database and AI platform to increase productivity and provide a clear competitive advantage for our users and partners.

World Tree grows Paulownia hardwood through regenerative forestry in partnership with farmers across the Americas.

YouAttest offers cloud based identity auditing solutions and management We Securely manage user access and ensure compliance with ease Get started today!

At Dardo Studios, we provide boutique solutions for comprehensive art creation, including concept art, 3D modeling, animation, VFX, and more. We also offer art direction, recruiting services, and expertise in structuring and managing art departments.

Connect your clients to trusted aging care experts quickly and seamlessly with bQuest. Become their go-to lifeline during family crises through our easy, vetted referral platform.

Timecap is a customizable habit tracker application designed to help users build healthy and productive habits.
Uscape Apparel LLC creates localized lifestyle apparel for collegiate, destination, and custom markets.
Squeeze Software, Inc. provides forward-thinking IT for businesses.

Facility Management Software designed to help businesses save time and money while providing real-time, actionable data.

Vincit is a Nordic digital business partner focusing on commercial solutions, enterprise platforms, and data & AI. We turn digital into business results by combining leading platforms and tailored solutions.

Essential HR Services is a team of experienced, professional Human Resources (HR) Consultants specializing in Labor Law Compliance, Employee Relations, HR Administration, Organizational Development, Training, Health and Wellness Programs, and Payroll. Our goal is to deliver quality service, with the utmost integrity.
Olobby is an all-in-one app for work that provides tasks, files, communication, and more, with both desktop and cloud solutions.
A better dating app, coming soon. Join the waitlist now.

Scientia Capital Management empowers retail investors with AI-powered investing, wealth management, and investment analysis. Smarter, risk-aware strategies for confident growth.

AccessStar empowers independent and meaningful lives for people with intellectual or developmental disabilities by providing various behavioral and developmental services such as group homes, community engagement, and nursing care.
Anchr provides AI agents for physical operations in industries such as food distribution, industrial and MRO, healthcare and pharma, building and technical supplies, and consumer packaged goods.
Synergetics.AI offers a trusted agentic infrastructure platform that allows AI agents to identify, communicate, and transact securely across enterprise boundaries.
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Boumarang builds hydrogen-powered, AI-enabled unmanned systems for air and maritime operations. Long endurance. Domestic IP. Dual-use by design.

Eagle Mountain Data provides next-generation infrastructure, including GPU services, storage, and networking, designed for complex AI workloads and real-time responsiveness at the edge.

The AI-native agency