
The Tongva village of Siutcanga once stood in what is now Encino, and in 1769 the Portolà expedition camped nearby while a Spanish missionary named the valley for its holm oaks, or "encinas." In 1845, Mexican governor Pío Pico granted Rancho Los Encinos, land from the secularized Mission San Fernando, to three Mission Indians; the adobe ranch house that followed still stands as Los Encinos State Historic Park. Sitting on a key travel route between Los Angeles and Santa Barbara, the rancho changed hands among Californio, French, and Basque families over the following decades. Encino was subdivided for residential development in the 1920s and grew into one of the San Fernando Valley's wealthiest neighborhoods.
Caramel is the safe & easy way to complete any private used car sale. Compatible with any car for sale by owner, Caramel does the DMV work & more for free.
Founded by Grammy-winning music producer BloodPop (known for work with Lady Gaga and Madonna), the game studio raised $6.5M in seed funding with a team including former Halo, Cyberpunk 2077, and Red Dead Redemption developers.

Between three square meals a day, there are a million little hunger stops. And for every balance bite, there's Sunnie - made for the in-between moments. We're here for snacking sustainably with no artificial anything - ever. Upgrade your snack routine and snack brighter.
Bridging international capital and know-how with African talent and enterprise since 2004, Helios Investment Partners manages funds totalling c. $3 billion.
NFTco was founded by serial entrepreneur Niel Robertson (previously of Trada and Newmerix), based in West Hollywood; the company later rebranded as 'Based,' an NFT trading platform, with Adam Lurie as CEO.

Modern California Cafe & Bakeshop in Encino, CA

CreatoRev is TikTok Shop's first licensed agency partner. We run mass creator campaigns, train top-selling talent, and produce shop livestreams for brands like L'Oréal, Maybelline, and Clarins across the US, UK, Mexico, Spain, and France.
Azora Therapeutics, an LA biopharma founded in 2019 by Matt Davidson and Julie Saiki, was acquired by Adial Pharmaceuticals in 2026 for up to $64 million.
Virtual Showroom Design operates as WeVisu, an AI-powered digital showroom platform for contractors and interior designers, founded by Betsalel Medioni and Moshe Fishbain.
Edit Hero was founded by Dean Shalit and builds an AI-enhanced editing platform that validates footage based on visual details, per Crunchbase.