
Carlsbad
The breakdown
49 startups on file in Carlsbad, spanning B2B, Healthcare, Consumer, 44 of 49 have disclosed funding, $1.2B combined, 13 at Series A stage, founding dates span 1967-2026.
A bit of history
Stanley Crooke founded Isis Pharmaceuticals in Carlsbad in 1989 to develop antisense therapy, a bet that took decades to pay off before Biogen partnership SPINRAZA won approval in 2016 and validated the whole platform; the company renamed itself Ionis Pharmaceuticals in 2015. That early antisense research base helped establish Carlsbad and the rest of San Diego's North County as a life-sciences cluster in its own right, distinct from but connected to San Diego's broader biotech scene to the south.
Sleep.ai; part of SleepScore Labs; provides B2B sleep intelligence solutions through APIs that power digital health; wellness; and consumer products. Originally founded in the Netherlands and later ac
DEBUT BIOTECHNOLOGY; INC. is a Carlsbad; California-based company founded in 2019.
GigaIO builds composable computing infrastructure; including its Gryf portable accelerator system; letting GPUs and storage be pooled and reconfigured for edge and datacentre workloads.
Airspace is a technology-enabled logistics service provider.
Medsphere supplies inpatient electronic health record software to hospitals and behavioural health facilities; alongside revenue cycle management; supply chain management and managed IT services.
U.S-based Cisco subsidiary designing fabless silicon photonics semiconductors.

Nalu Medical offers a neurostimulation system that provides a long-term solution for managing intractable chronic nerve pain.
Equip Health provides virtual eating disorder treatment through a 5-person care team that includes a therapist, medical provider, dietitian, family mentor, and peer mentor.
Co-founded in 2018 by Scott Glenn and Lauren Otsuki, the skincare-tech company (parent of the Ourself brand) is backed by Lightspeed Venture Partners and added former Allergan CEO Brent Saunders to its board.

Ceresti reduces hospitalizations and medical costs for people living with dementia by activating family caregivers to detect changes in the patient's condition.

Proper Voltage is the digital bridge that seamlessly links power and product, opening up access to more choices and possibilities.
The entity behind Nixon, the watch and accessories brand founded in 1997 by Andy Laats and Chad DiNenna, which is now backed by private equity firm Trilantic Capital Management.
German skincare giant Beiersdorf (maker of Nivea) became an investor in the company; Amicrobe later rebranded as Macro Biologics.

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Rapalogix is advancing a portfolio of TORC1-selective therapies and pro-longevity skincare products, addressing skin aging and disease at the root to extend skin healthspan.

Electrolytes formulated with premium, all-natural and organic ingredients. Instant Hydration replenishes you faster and longer than water alone.
This Carlsbad, CA private-equity vehicle for engineered stone manufacturing is run by managing member Oren Klaff, the investor and author best known for the bestselling sales book "Pitch Anything."
Founded by physician-entrepreneur Remo Moomiaie-Qajar, M.D.; the San Diego biotech has raised $14.4M in funding, including from Partners Investment.
RCE Technologies is developing Infrasensor™, a non-invasive wearable that uses infrared spectroscopy and machine learning to detect severe coronary artery occlusion in about three minutes, without a blood draw — aimed at catching the 60%+ of heart attacks that standard chest-pain triage misses.

MUNICIPAL was founded in 2019 to inspire people to bet on themselves and make big things happen. The apparel & footwear we create combines best-in-class quality, versatile performance and extreme comfort.
Nasdaq-listed (QLGN); received a $41 million strategic PIPE investment from Faraday Future, whose founder is Chinese entrepreneur YT Jia (Jia Yueting).

ChromaCode is a leading provider of HDPCR™ multiplexing technology for genomic solutions. Our breakthrough platform enables labs, physicians, and patients to access actionable biomarkers faster and more affordably. With HDPCR™, you can get critical and complete data, analyzed with simplicity, without paying for excess information.
Co-founded by Jeffrey Port and William Blair; the company was acquired by Merit Medical Systems, expanding Merit's therapeutic oncology portfolio.

Virgo builds frontier AI models to solve diseases mediated by the gut. Our flagship model, EndoDINO, was trained on the largest GI endoscopy dataset.
Co-founded by Andrew Morris, Eric Brouwer, and Adolfo Velazquez, the company is developing a rapid lung-cancer diagnostic called the verifi LUNG test.

Effortless, science-backed oral microbiome insights from saliva. Decode your saliva for personalized wellness.
Through its health & fitness AI platform, PEAR creates personalized digital coaching experiences to help people move smarter, get healthier, and live happier.

Priwall helps you find and remove your personal data from data brokers. Protect your identity and reduce your digital footprint.
Ponto is a financial infrastructure company

SAFR Football Helmet Covers reduce the external blunt force that can cause traumatic brain injuries for all ages. Learn more!

Multi-carrier wireless internet for homes, businesses, and specialized equipment. No contracts, 24/7 support, and reliable connectivity across all 50 states.
LenderSquared provides a Unified Intelligence Platform that integrates data, AI, and analytics to help modern lenders evaluate risk, automate workflows, and fund faster with clarity and control.

The Vesteck Inc Endosuture Aneurysm Repair (ESAR) platform, Suture-Tight™, is revolutionizing the aneurysm repair space.
Struggling with your mental health? Our online counsellors meet with you through our video counselling platform, when and where it works best for you.

HAUSER is a world-class musician and magician of the cello. His passion is to show his audience the versatility of the cello. Watch latest videos and events!
ClearPrice Networks, Inc. connects payers and providers directly, transparently, and electronically to eliminate rebilling vendor markups for DME, Orthotics & Prosthetics, Medical Supplies, and Home Care Services.
Renova Therapeutics is focused on developing definitive treatments to restore health to people suffering from congestive heart failure and type 2 diabetes through transformational gene therapies.

Bristlecone is the leading provider of connected logistics solutions, including AI applications, SAP integration, and more.
Founded by MaryRose Reaston (co-founder/CSO) alongside CEO Brett Ottemeier; the Carlsbad-based company makes functional EMG diagnostic technology and has won an industry innovation award.

Multi-model AI with a patent-pending AI Firewall — for teams where data privacy is not optional. 47 models, one workspace, sensitive data stays home.

Macro Biologics designs, patents, and produces advanced biomaterials for healthcare, food and water applications, and packaging.

Colorescience offers mineral sunscreens and clinical skincare products.

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Float is the full-stack platform for Specialty Pharma