Southern California's
Startup Directory
Every VC-backed and bootstrapped startup founded in Los Angeles, Orange County, San Diego, the Inland Empire, and Ventura — company profiles, funding rounds, and the investors and accelerators actually writing checks in the region, not a national list with a few SoCal names mixed in.
SeedStaxiom provides diligence-grade accounting for startups — bookkeeping, tax prep, and capital strategy, with an AI-assisted R&D tax credit engine reviewed by EY-trained CPAs. Founded by the team behind Ardius, the R&D tax credit company Gusto acquired in 2021.
Pre-Seed$4.0MSocialCrowd automatically tracks employee progress towards goals, reminds them of the work they have left, and rewards them instantly – so you can save time and stay focused!
Pre-Seed$250KBetter, faster tech vendor research
Series D$833.1MWe provide efficient in-space mobility that moves payloads from low Earth orbit to any destination. Our vehicles deliver rapid, reliable access, reducing costs and timelines to make space operations feasible for commercial, government, and scientific missions.
Series D$36.5MNutrition and longevity company behind the Fasting Mimicking Diet (Prolon), founded by USC's Dr. Valter Longo.
Series D$42.2MRenata Medical develops cardiovascular devices for children with congenital heart disease. Its Minima Stent System is the first balloon-expandable growth stent designed for neonates; infants and young
Series D$1.37BHadrian is building highly automated factories to manufacture critical components and systems for defense and aerospace.
Series D$204.5MObsidian Security protects the SaaS applications a company runs on; from Newport Beach; founded in 2017. It sells posture management and governance for third-party apps - Microsoft 365; Google Workspa
Series D$441.7MNetradyne engages in improving fleet safety through computer vision and in-depth data analysis.
Series D$407.5MSpacecraft represent the most pressing need across the entire aerospace industry. As more launch vehicles come online and the cost to orbit decreases; more companies launching payloads to space contin
Series D$191.0MBoulevard is a business management platform developed to help streamline the operations of appointment-based businesses.
Series D$60.0MFounded in 2016 and headquartered in San Diego; Clearspeed provides voice-based risk assessment software that returns real-time risk indicators for insurance; government; defense; and financial-servic
EXPLORE TOP CITIES
WHAT SOUTHERN CALIFORNIA BUILDS
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Pharmaceutical & Biopharma
Drug developers and biopharma platforms, concentrated in San Diego's Torrey Pines corridor and the LA biotech cluster. Searched as "pharmaceutical companies in San Diego / Orange County" more than any other industry phrase in our Search Console data.
Biotechnology & Life Sciences
The life-science research base behind San Diego's and Los Angeles's biotech reputations: platforms, tools, diagnostics and therapeutics spun out of UCSD, Scripps, Caltech and UCLA.
Software & SaaS
Software companies across the region, from Irvine's enterprise SaaS bench to Santa Monica's consumer apps: the broadest category here after AI, and the one people search for by city.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.