Pharmaceutical & Biopharma startups in Southern California
Drug developers and biopharma platforms, concentrated in San Diego's Torrey Pines corridor and the LA biotech cluster. Searched as "pharmaceutical companies in San Diego / Orange County" more than any other industry phrase in our Search Console data.
Companies
Pharma and medical-device compliance software plus licensing consulting.
Develops FDA-authorized virtual reality therapeutics, including RelieVRx (formerly EaseVRx), a prescription VR program for chronic lower back pain.
Daré Bioscience (Nasdaq: DARE) is a San Diego-based biopharmaceutical company developing and commercializing therapies for women's reproductive and sexual health, an area of medicine it argues has been chronically underfunded relative to its size.


Aggregates medical records from doctors, clinics, hospitals, labs, and pharmacies into one shared patient workspace.
Khartis Therapeutics is a San Diego biotechnology company developing oral small-molecule medicines targeting clinically validated immunology pathways. Its lead program is an oral; selective IGF-1R inh
Amplifica is a San Diego clinical-stage biopharmaceutical company developing injectable treatments for hair loss. Rather than slowing loss; its approach works on the signalling molecules that govern t
Crystalys Therapeutics is a San Diego clinical-stage biotechnology company developing treatments for gout; a disease it argues remains badly served despite being common. Its lead candidate is in pivot
Wugen is an off-the-shelf Cell Therapies for Cancer founded by Matthew Cooper; Todd Fehniger; Melissa Berrien-Elliott and John DiPersio.
Founded in 2017; Onchilles Pharma is a drug-discovery and development company pioneering first-in-class cytotoxic therapies that selectively kill cancer cells while preserving and activating immune fu
Arnatar Therapeutics develops RNA medicines from a platform it calls DARGER; which pairs highly active siRNA for silencing a gene with ACT-UP1; an antisense technology that does the opposite and incre
Entos Pharmaceuticals develops nucleic acid-based therapies using its proprietary Fusogenix drug delivery system.
Lomond Therapeutics creates pharmacological platforms that target escape mutations.
Dyania Health develops a research platform for pharma companies and hospital systems.
Terray Therapeutics is a Los Angeles-based biotechnology company that combines ultra-high throughput experimentation; generative AI; biology; medicinal chemistry; automation; and nanotechnology to exp
Escient Pharmaceuticals is a GPCR-targeted Drugs founded in 2018.
Alterome Therapeutics; Inc. is an oncology Treatments founded in 2021 by Eric Murphy.
Abintus Bio; Inc. is a San Diego-based; preclinical stage gene therapy company focused on the discovery and development of a portfolio of product candidates that are designed to directly reprogram imm
A biotechnology company focused on the discovery and development of next-generation therapeutics.
Shoreline Biosciences; Inc. is a Cell-Based Immunotherapies; founded in 2020. It has raised $229M across 4 funding rounds; most recently a $140M in November 2021; from investors including Janus Capita
Kumquat Biosciences is a San Diego-based biotechnology company focused on the research and development of oncology medicines.
Aristea Therapeutics is a small Molecules founded in 2018.
Operator of a biotechnology company intended to improve outcomes for people with cancer. The company offers a pipeline against validated oncology targets to deliver radioisotopes that emit alpha parti
BioTheryX is a small Molecules founded in 2008.
Phanes Therapeutics is a treatments for solid tumors and eye diseases.
Biosplice Therapeutics is a clinical-stage biotechnology company developing lorecivivint; an injectable small-molecule CLK/DYRK-family inhibitor for knee osteoarthritis.
Fortis Therapeutics is a San Diego; CA-based immuno-oncology biotech company
Neurelis Inc. is a private specialty pharmaceutical company based in San Diego; California; US; providing treatment options for epilepsy and central nervous system disorders.
DTx Pharma; Inc. is a San Diego-based company.
Vividion Therapeutics is a proprietary Screening founded in 2017.
Pipeline Therapeutics is a small Molecule for MS founded in 2017.
A biopharmaceutical company developing protein therapeutics
Output is a United Kingdom-based company.
Novus Therapeutics is an Irvine; California-based company founded in 2017.
Libra Therapeutics is a small Molecules for Neurodegenerative Indications founded in 2019.
Amplyx Pharmaceuticals; Inc. is a preclinical stage company focusing on the development of small molecule drugs.
GPB Scientific is an automation of Cell Therapy Manufacturing.
Cold Genesys is a privately-held; immunotherapy based biopharmaceutical company
Mirum Therapeutics is a San Diego-based company in the pharmaceutical industry.
Qpex Biopharma is a San Diego-based company founded in 2018.
Neurana Pharmaceuticals is a small Molecule.
Synthetic biology company that created novel DNA base pairs and uses them to incorporate novel amino acids into proteins for potential therapeutics in areas of cancer and autoimmune disorders.
A company focused on developing products for oncology surgery and therapeutic intervention
Bioniz is a multi-cytokine inhibitory therapeutics.
A biotechnology company developing molecular-based diagnostic; prognostic; and predictive medical tests designed to help healthcare practitioners treat cancer.
Cerulean Pharma; Inc is a company founded in 2006 by Ram Sasisekharan.
Crown Bioscience is a contract research organisation for drug discovery; best known for oncology models and also working in cardiovascular and metabolic disease; with sites across the United States; E
A company developing therapeutics for veterinary medicine
A biopharmaceutical company that develops therapeutics to treat depressive disorders
A biotechnology company developing cancer therapeutics based on antibodies
A company that develops therapeutics for the treatment of cancer
GeneTex is a research Antibodies founded in 1997.
CombiMatrix is an Irvine; California-based healthcare company developing products and service for drug development; genetic analysis and diagnostics.
Femta Pharmaceuticals is a biotechnology company that develops protein therapeutics
A company developing biologically active compounds and drug candidates
A company developing pharmaceutical and diagnostic products to help physicians personalize patient care
A biopharmaceutical company developing small molecule therapeutics for respiratory and inflammatory disorders
Genoptix is a Carlsbad; California-based medical diagnostics company offering next-generation sequencing for oncology founded in 1999 by Tina Nova.

Developing the next generation of oncology therapies for patients.
Mirador Therapeutics is focused on discovering and developing precision medicines for immune-mediated inflammatory and fibrotic diseases using its Mirador360™ engine, which harnesses biology, multi-modal data, AI, and advanced analytics.
Avidity Biosciences is a company driven by the mission to profoundly improve people's lives by revolutionizing a new class of targeted RNA therapeutics through its Antibody Oligonucleotide Conjugates (AOC™) platform.