Southern California's
Startup Directory
Series B$84.3MRebuilding healthcare with AI at the core
Pre-Seed$250KBetter, faster tech vendor research
Series D$833.1MWe provide efficient in-space mobility that moves payloads from low Earth orbit to any destination. Our vehicles deliver rapid, reliable access, reducing costs and timelines to make space operations feasible for commercial, government, and scientific missions.
Series C$80.1MOutpace AI-driven attacks. Unify Digital Risk Protection, Human Risk Management, and Email Security to stop digital threats before they scale, empower your teams to lead your defense, and scale your SOC with agentic AI.
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
Series A$23.5MAccess to Social Security 3-5 days early.
Series A$23.2MQuintessent is developing optical connectivity solutions to scale computing and Artificial Intelligence (A.I.).
$23.1MThe entity behind Nixon, the watch and accessories brand founded in 1997 by Andy Laats and Chad DiNenna, which is now backed by private equity firm Trilantic Capital Management.
Series A$22.6MThe 1st warehouse-native platform for experimentation, feature flags, and product analytics. Open source and fully transparent. Trusted by 3,000+ companies.
Series A$22.4MWelcome to VIAVIA! Redefining the fashion experience for a new generation // Enjoy free shipping and returns on all orders // New Designers and products dropping daily
Serimmune was founded by Patrick Daugherty, a former UC Santa Barbara chemical engineering professor who also co-founded CytomX Therapeutics; backers include Illumina Ventures, LabCorp, and Merck.
Series A$22.0MFounded in 2019 by Marc Washington, who previously grew Beachbody into a $1 billion+ company; the LA-based startup (maker of Muniq gut-health shakes) raised an $8.2M Series A backed by venture foundry The Production Board.