Southern California's
Startup Directory
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Early StageCosight builds always-connected telehealth devices — cellular- and satellite-ready — for video consultations and remote patient monitoring, with real-time translation and integration with FDA-approved medical devices, aimed at hospitals and healthcare providers.
Pre-Seed$250KBetter, faster tech vendor research
Series D$833.1MWe provide efficient in-space mobility that moves payloads from low Earth orbit to any destination. Our vehicles deliver rapid, reliable access, reducing costs and timelines to make space operations feasible for commercial, government, and scientific missions.
Series C$80.1MOutpace AI-driven attacks. Unify Digital Risk Protection, Human Risk Management, and Email Security to stop digital threats before they scale, empower your teams to lead your defense, and scale your SOC with agentic AI.
EXPLORE BY CITY
WHAT SOUTHERN CALIFORNIA BUILDS
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
Series A$607KBerman Medical is a San Diego medical-imaging AI startup founded in 2024 by co-founder and CEO Andrew Hanna, and has raised about $607K to date.
Series A$600KCreatoRev is TikTok Shop's first licensed agency partner. We run mass creator campaigns, train top-selling talent, and produce shop livestreams for brands like L'Oréal, Maybelline, and Clarins across the US, UK, Mexico, Spain, and France.
$600KSpinasana offers a balanced mix of premium rhythmic spin and hot yoga classes designed to strengthen, stretch and rejuvenate the body. Flexible membership options in Pasadena, CA.
Series A$600KCreate engaging, interactive presentations effortlessly with Tiled. Enhance your storytelling and captivate your audience with dynamic, customizable content.
Pre-Seed$600KGolf training studios with expert coaching, tour-level tech, fitness training, and custom club fitting. Locations in AZ, CA, and TX.
Seed$581KAzora Therapeutics, an LA biopharma founded in 2019 by Matt Davidson and Julie Saiki, was acquired by Adial Pharmaceuticals in 2026 for up to $64 million.
Seed$578KVirtual Showroom Design operates as WeVisu, an AI-powered digital showroom platform for contractors and interior designers, founded by Betsalel Medioni and Moshe Fishbain.