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Southern California's
Startup Directory

BlossomHill Therapeutics, Inc. hero photo
Series B$172.8M
BlossomHill Therapeutics, Inc.
San Diego, CA · Founded 2020

We are on a mission to exponentially improve the number of quality years for patients.

Series BHealthcare
ModRetro, Inc. hero photo
Series F$164.3M
ModRetro, Inc.
Irvine, CA · Founded 2023

ModRetro brings the best of the past to modern consumer electronics, for those who crave technology with a human soul.

Series FB2B
CaskX LLC hero photo
$161.8M
CaskX LLC
Beverly Hills, CA · Founded 2020

CaskX offers whiskey cask investment and American bourbon barrel investment products to investors around the globe. Start your whiskey portfolio now.

B2B
$160.0M
HWOOD GROUP, LLC
West Hollywood, CA

The h.wood Group is a Los-Angeles based hospitality and lifestyle company with a diversified portfolio of upscale nightlife & restaurant venues.

Consumer
Series C$158.3M
TORL Biotherapeutics LLC
Culver City, CA

Founded in 2019 with co-founder Dave Licata, and has raised over $450 million total, with investors including Goldman Sachs Asset Management and Blue Owl Capital.

Series CHealthcare
Series B$155.8M
Equip Health, Inc.
Carlsbad, CA · Founded 2019

Equip was co-founded by CEO Kristina Saffran, who drew on her own recovery from anorexia; she previously co-founded the nonprofit Project Heal. Actress Kerry Washington has also personally invested in the company.

Series BHealthcare
Skye Bioscience, Inc. hero photo
Series B$152.2M
Skye Bioscience, Inc.
San Diego, CA

We are a biopharmaceutical company focused on the development of proprietary cannabinoid derivatives for the treatment of glaucoma and other diseases with significant unmet medical needs. Our innovative approach to drug development combines strong science with the drive to find solutions where the need is the greatest.

Series BHealthcare
Series C$152.1M
Lightship Inc.
El Segundo, CA · ~51-200 employees

Lightship is a clinical trial site network that expands participant choice through in-clinic, hybrid, virtual, and mobile research models.

Series CHealthcare
A futuristic humanoid robot in an indoor Tokyo setting, showcasing modern technology.

Artificial Intelligence

The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.

107 in our directoryView all →
Dramatic view of rocket boosters against a bright blue sky, showcasing aerospace technology.

Aerospace & Defense

Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.

40 in our directoryView all →
A behind-the-scenes look at a filming crew setting up a scene indoors with lighting equipment.

Entertainment & Gaming Tech

Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.

38 in our directoryView all →
Detailed view of a motherboard with visible microchips and circuits.

Semiconductor Hardware

Qualcomm and Broadcom anchor a chip-design cluster spanning the region.

7 in our directoryView all →
A healthcare worker operates a modern infusion pump in a hospital setting, ensuring precise medication delivery.

Medical Technology

A deep biotech research base and a growing bench of medical device and diagnostics startups.

290 in our directoryView all →
Laptop on office desk with a city skyline through a large window, offering a modern workspace view.

B2B

Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.

909 in our directoryView all →
Modern industrial machine in operation in a manufacturing facility showcasing advanced technology.

Industrials

Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.

93 in our directoryView all →
A woman helps a man choose a shirt in a modern clothing store.

Consumer

Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.

135 in our directoryView all →
High-tech laboratory equipment with multiple vials in a scientific research facility.

Healthcare

Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.

247 in our directoryView all →
Bitcoin coin with financial data, credit cards, and currency on a desk.

Fintech

Financial technology: payments, banking, investing, and financial infrastructure.

23 in our directoryView all →
A group of students attending a lecture wearing school uniforms, focused and attentive.

Education

Education technology and learning platforms built across Southern California.

3 in our directoryView all →
A construction worker operating a concrete mixer at an active building site, emphasizing safety gear.

Real Estate & Construction

Property technology, construction tech, and real estate services.

13 in our directoryView all →