Southern California's
Startup Directory
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Early StageCosight builds always-connected telehealth devices — cellular- and satellite-ready — for video consultations and remote patient monitoring, with real-time translation and integration with FDA-approved medical devices, aimed at hospitals and healthcare providers.
Pre-Seed$250KBetter, faster tech vendor research
Series D$833.1MWe provide efficient in-space mobility that moves payloads from low Earth orbit to any destination. Our vehicles deliver rapid, reliable access, reducing costs and timelines to make space operations feasible for commercial, government, and scientific missions.
Series C$80.1MOutpace AI-driven attacks. Unify Digital Risk Protection, Human Risk Management, and Email Security to stop digital threats before they scale, empower your teams to lead your defense, and scale your SOC with agentic AI.
EXPLORE BY CITY
WHAT SOUTHERN CALIFORNIA BUILDS
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
Series A$765KFounded by Mark De Roche, Aerofex built the Aero-X, one of the first working hoverbikes, and is based in Los Angeles.
Series A$762KGRI Bio is a publicly traded clinical-stage biopharmaceutical company (Nasdaq: GRI), led by CEO Marc Hertz, PhD.
$755KFiGPiNS are hand-crafted enamel character pins featuring a patented backer that serves as a pin clasp AND display stand! FiGPiN elevates collectible pins!
Series A$750KAlderbuck Energy is modernizing power distribution with solid-state transformer technology built for the electricity demands of AI, EVs, and the modern grid.
$750KSalon Republic is the industry leader of modern salon suites for rent for beauty professionals. Join our community - the place to go for salon rental space.
$750KGenseeAI, an AI agent infrastructure startup, was co-founded by UC San Diego professor Dr. Yiying Zhang and former Google tech lead Dr. Shengqi Zhu, and is backed by Two Small Fish Ventures.