Southern California's
Startup Directory
Series B$84.3MRebuilding healthcare with AI at the core
Pre-Seed$250KBetter, faster tech vendor research
Series D$833.1MWe provide efficient in-space mobility that moves payloads from low Earth orbit to any destination. Our vehicles deliver rapid, reliable access, reducing costs and timelines to make space operations feasible for commercial, government, and scientific missions.
Series C$80.1MOutpace AI-driven attacks. Unify Digital Risk Protection, Human Risk Management, and Email Security to stop digital threats before they scale, empower your teams to lead your defense, and scale your SOC with agentic AI.
EXPLORE BY CITY
WHAT SOUTHERN CALIFORNIA BUILDS
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
Growthsayer was founded by Phillip Geltman, a San Diego-based supply chain specialist who originally built the platform to optimize cannabis industry supply chains before expanding into broader retail demand planning.
$2.2MEco-luxury clothing from regenerative materials. TreeSilk TENCEL-blend, GOTS organic cotton, European Flax. Made in LA. Every purchase plants a tree.
$2.2MUnlock the power of data-driven investing with Bancreek Capital Advisors. Explore our actively managed ETFs and interactive visualization tools for smarter investment decisions.
Seed$2.2MEmpowering Indie Artists to Connect, Grow, and Earn - OpenWav
Hualapai Ventures, a Beverly Hills-based entity, has been reported as the front company behind TKO Group's (UFC/WWE parent) new boxing league venture.
Seed$2.2MAtmosphere Data Centers, led by CEO Chuck McBride, secured a strategic growth investment from global institutional investor AGC Equity Partners in 2025.
Seed$2.2MHauler Hero is a waste management software solution that helps waste haulers improve their operations, increase efficiency, and reduce costs.
$2.2MSpecialist Wealth Management