Southern California's
Startup Directory
Series B$84.3MRebuilding healthcare with AI at the core
Pre-Seed$250KBetter, faster tech vendor research
Series D$833.1MWe provide efficient in-space mobility that moves payloads from low Earth orbit to any destination. Our vehicles deliver rapid, reliable access, reducing costs and timelines to make space operations feasible for commercial, government, and scientific missions.
Series C$80.1MOutpace AI-driven attacks. Unify Digital Risk Protection, Human Risk Management, and Email Security to stop digital threats before they scale, empower your teams to lead your defense, and scale your SOC with agentic AI.
EXPLORE BY CITY
WHAT SOUTHERN CALIFORNIA BUILDS
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
Seed$2.8MOption-based portfolio strategies for RIAs and institutional investors — risk-managed income, growth with loss limits, and VOLT™, our tax-smart option overlay for concentrated stock.
MDFZ, LLC is a wholly owned subsidiary of Legion M Entertainment, the self-described "world's first fan-owned entertainment company," per Legion M's SEC offering filings.
Seed$2.7MZymbit Resilient Edge Stack makes Linux devices more secure, reliable and recoverable. Trusted software and hardware that grows with your business.
$2.7MCo-founded by CEO Scott Stout, recognized as one of 2021's top healthcare innovators, and Dr. Dennis Patterson; the El Segundo company builds decentralized clinical-trial technology.
$2.7MBESPOKE SOLUTIONS FOR A DYNAMIC M&A ENVIRONMENT.
Founded in 2021 by sneaker reseller Wayne Mocadlo with his brother John Mocadlo as COO, Impossible Kicks grew into one of the largest sneaker and streetwear resale chains in the US and has raised funds via equity crowdfunding.
Founded in 2023 by games-industry veterans J Aaron Farr, M Yichao, and T Carl Kwoh (with backgrounds at Riot Games and Wizards of the Coast), the studio raised a $3.15M seed round led by London Venture Partners.
Series A$2.6MNew: Custom prescription hair growth formulas from board-certified dermatologists. 200+ Rx formulations with FDA-approved ingredients. 1M+ prescriptions delivered. Start your free assessment.