Southern California's
Startup Directory
Series B$84.3MRebuilding healthcare with AI at the core
Pre-Seed$250KBetter, faster tech vendor research
Series D$833.1MWe provide efficient in-space mobility that moves payloads from low Earth orbit to any destination. Our vehicles deliver rapid, reliable access, reducing costs and timelines to make space operations feasible for commercial, government, and scientific missions.
Series C$80.1MOutpace AI-driven attacks. Unify Digital Risk Protection, Human Risk Management, and Email Security to stop digital threats before they scale, empower your teams to lead your defense, and scale your SOC with agentic AI.
EXPLORE BY CITY
WHAT SOUTHERN CALIFORNIA BUILDS
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
Series B$4.9MThe world’s leading platform for packaging and financing independent films, with tools for filmmakers, talent, and investors to connect and succeed.
$4.9MAs leaders in cathode innovation, we develop materials that drive clean energy solutions. Click here to explore our pioneering work in battery technology.
Seed$4.9MCo-founded by Brian Wong, who previously founded Kiip, a mobile rewards-platform startup he built starting at age 19 that made him one of Silicon Valley's youngest venture-backed CEOs.
Series A$4.9MAn easy-to-launch mixed reality platform that blends physical and digital experiences for unparalleled fan engagement. Request a demo.
Series A$4.8MFounded in 2017 by Dr. Hoon Kim, who brought over 20 years of academic R&D experience in nanoengineered CMOS image sensors to the company's quantum image sensor technology.
Series A$4.8MSlips is the next-generation peer-to-peer betting platform where players bet against each other — not the house. Offering Heads Up, Pools, Tourlays, and AI-Generated Predictions, Slips creates a social-first experience where users win, connect, and compete in real time.
Seed$4.8M
Series A$4.8MCo-owned by Issa Rae & Hannah Diop, Sienna Naturals is a vegan hair care line that delivers results. The line is specifically formulated to hydrate textured hair, revive your curl pattern, and repair styling damage.