Southern California's
Startup Directory
Series B$84.3MRebuilding healthcare with AI at the core
Pre-Seed$250KBetter, faster tech vendor research
Series D$833.1MWe provide efficient in-space mobility that moves payloads from low Earth orbit to any destination. Our vehicles deliver rapid, reliable access, reducing costs and timelines to make space operations feasible for commercial, government, and scientific missions.
Series C$80.1MOutpace AI-driven attacks. Unify Digital Risk Protection, Human Risk Management, and Email Security to stop digital threats before they scale, empower your teams to lead your defense, and scale your SOC with agentic AI.
EXPLORE BY CITY
WHAT SOUTHERN CALIFORNIA BUILDS
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
$6.0MA visual conversation at the speed of culture
Series A$6.0MAI workers that quote, dispatch, track, and close loads. Phone, email, WhatsApp. 28 languages, 24/7. Runs inside your TMS.
Seed$6.0MDeveloping novel long-acting therapeutics targeting chronic cardiometabolic diseases.
Seed$6.0MKeeta is a layer-1 blockchain network that connects payment networks. Direct blockchain-to-blockchain transactions are processed with settlement times of 400 milliseconds and a throughput of 10 million transactions per second.
Series A$5.7MPoolsuit, Powersuit, Playsuit. Do it all in one suit. Left On Friday is a premium active swimsuit brand. Designed for sport. Destined for fun.
Series A$5.7MGain unprecedented kinetic insights into your CRISPR workflow with the CRISPR QC’s analytics platform
$5.7MSunshine Holdings PLC is a diversified Sri Lankan conglomerate engaged in the healthcare, consumer goods, and agribusiness sectors in Sri Lanka.