Southern California's
Startup Directory
Series B$84.3MRebuilding healthcare with AI at the core
Pre-Seed$250KBetter, faster tech vendor research
Series D$833.1MWe provide efficient in-space mobility that moves payloads from low Earth orbit to any destination. Our vehicles deliver rapid, reliable access, reducing costs and timelines to make space operations feasible for commercial, government, and scientific missions.
Series C$80.1MOutpace AI-driven attacks. Unify Digital Risk Protection, Human Risk Management, and Email Security to stop digital threats before they scale, empower your teams to lead your defense, and scale your SOC with agentic AI.
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
Seed$6.6MRypplzz is the 3D positioning infrastructure that transforms telecom networks into spatially intelligent systems, powering the next evolution of the internet.
Elodie Games was co-founded by Riot Games/League of Legends veterans Christina Norman and David Banks, and raised $32.5M in Series A funding backed by Andreessen Horowitz before shutting down in 2025.
Mosh, the brain-health protein bar brand, was co-founded by Maria Shriver and her son Patrick Schwarzenegger, and raised a $13M Series A led by Main Street Advisors.
$6.5MMeasurabl offers comprehensive ESG solutions, empowering businesses with data-driven insights for sustainability & compliance. Learn More
Series B$6.5M
Series A$6.5MArena Club, an online sports card marketplace, was co-founded by entrepreneur Brian Lee (co-founder of LegalZoom/ShoeDazzle/The Honest Company) and Baseball Hall of Famer Derek Jeter, and raised a $10M Series A.
Series B$6.5MIndependa Health Hub® is a simple to use ecosystem of health & wellness benefits on any screen — TV, tablet, computer, or phone. Many benefits absolutely FREE!
Series B$6.5MORANGE COMET is a next-generation gaming and entertainment company creating immersive games in partnership with the biggest properties in the world.