Southern California's
Startup Directory
Series B$84.3MRebuilding healthcare with AI at the core
Pre-Seed$250KBetter, faster tech vendor research
Series D$833.1MWe provide efficient in-space mobility that moves payloads from low Earth orbit to any destination. Our vehicles deliver rapid, reliable access, reducing costs and timelines to make space operations feasible for commercial, government, and scientific missions.
Series C$80.1MOutpace AI-driven attacks. Unify Digital Risk Protection, Human Risk Management, and Email Security to stop digital threats before they scale, empower your teams to lead your defense, and scale your SOC with agentic AI.
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
Series A$8.5MGet instant real-time visibility with EdgeX. Wire-free RTLS, asset tracking, and environmental monitoring. Fast ROI, no IT burden, deployed in hours.
Cre8tech Labs does business as Lender Price, a mortgage fintech that received a strategic investment from Regions Bank in 2018.
DermOQ was founded by Bradley Patt, who previously served as CEO of medical imaging company Gamma Medica.
Seed$8.3MTransform job-site drawings into actionable tools for tracking every building element from day one.
Series A$8.3MBuild, deploy, and govern autonomous digital workers across revenue, IT, service, and operations. Automate workflows, execute tasks, and scale work with AI-powered digital workers.
Series B$8.3MMSI is the single platform for medical device cybersecurity compliance — tools, data, and expert support to meet FDA requirements and ship on schedule. 100% FDA approval rate.
Series A$8.2MZuub raised a $9M Series A led by Vertical Venture Partners, with Bonfire Ventures also participating.
$8.2MMUNICIPAL was founded in 2019 to inspire people to bet on themselves and make big things happen. The apparel & footwear we create combines best-in-class quality, versatile performance and extreme comfort.