Southern California's
Startup Directory
Series B$84.3MRebuilding healthcare with AI at the core
Pre-Seed$250KBetter, faster tech vendor research
Series D$833.1MWe provide efficient in-space mobility that moves payloads from low Earth orbit to any destination. Our vehicles deliver rapid, reliable access, reducing costs and timelines to make space operations feasible for commercial, government, and scientific missions.
Series C$80.1MOutpace AI-driven attacks. Unify Digital Risk Protection, Human Risk Management, and Email Security to stop digital threats before they scale, empower your teams to lead your defense, and scale your SOC with agentic AI.
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
$10.0MLearn how Genomic Life enhances health and well-being through genetic screenings, early detection, personalized cancer navigation, and ongoing support. Optimize employee benefits and create a healthier workforce.
Seed$10.0MExplore Starlings
Seed$10.0M
Series A$10.0MAllVoices is the AI-native employee relations platform for anonymous reports, cases, and investigations. Save hours with AI case summaries and reports.
Series B$10.0MTopicals is transforming the way you feel about skin through effective science backed products for chronic skin conditions and mental health advocacy.
Seed$10.0MCo-founded by Prakash Chandran, Xano raised a $5M round led by MHS Capital and Engineering Capital to build its no-code backend development platform.
Founded by Grammy-winning music producer BloodPop (known for work with Lady Gaga and Madonna), the game studio raised $6.5M in seed funding with a team including former Halo, Cyberpunk 2077, and Red Dead Redemption developers.
Seed$9.8MFounded by Dr. S. Eric Ryan, a former Volcano Corporation VP, Provisio Medical develops intravascular ultrasound smart-catheter technology and has raised tens of millions in venture funding, including backing tied to MedTech Innovator.