Southern California's
Startup Directory
Series B$84.3MRebuilding healthcare with AI at the core
Pre-Seed$250KBetter, faster tech vendor research
Series D$833.1MWe provide efficient in-space mobility that moves payloads from low Earth orbit to any destination. Our vehicles deliver rapid, reliable access, reducing costs and timelines to make space operations feasible for commercial, government, and scientific missions.
Series C$80.1MOutpace AI-driven attacks. Unify Digital Risk Protection, Human Risk Management, and Email Security to stop digital threats before they scale, empower your teams to lead your defense, and scale your SOC with agentic AI.
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
$15.8M
Series B$15.8MAn integrated communications platform using cloud-hosted phone, chat, contact center and analytics to meet the challenges of today’s business.
Series A$15.7MModel Medicines engineers first-in-class small molecules against biological choke points, using AI to advance pipeline-in-a-pill therapeutics across high-impact diseases.
$15.7MRadical Group Inc. is the legal entity behind Intro (intro.co), a marketplace where users book paid one-on-one video calls with celebrities and experts; it was founded in 2017 in the LA area.
Series A$15.6MPrice transparency and plan design tools for self-funded health plan comparisons and enhanced employee benefits strategies.
Series A$15.6Mhuupe brings you the world’s first smart basketball hoop, providing NBA level workouts, on-demand training, live coaching, data tracking and more.
Series B$15.6M
Series B$15.5MSyndex Bio was founded by Geoff Smith and raised a $15.5M seed round backed by ARCH Venture Partners, one of the top-tier biotech venture firms.