Southern California's
Startup Directory
Series B$84.3MRebuilding healthcare with AI at the core
Pre-Seed$250KBetter, faster tech vendor research
Series D$833.1MWe provide efficient in-space mobility that moves payloads from low Earth orbit to any destination. Our vehicles deliver rapid, reliable access, reducing costs and timelines to make space operations feasible for commercial, government, and scientific missions.
Series C$80.1MOutpace AI-driven attacks. Unify Digital Risk Protection, Human Risk Management, and Email Security to stop digital threats before they scale, empower your teams to lead your defense, and scale your SOC with agentic AI.
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
Series A$765KFounded by Mark De Roche, Aerofex built the Aero-X, one of the first working hoverbikes, and is based in Los Angeles.
Series A$762KGRI Bio is a publicly traded clinical-stage biopharmaceutical company (Nasdaq: GRI), led by CEO Marc Hertz, PhD.
Series A$750KAlderbuck Energy is modernizing power distribution with solid-state transformer technology built for the electricity demands of AI, EVs, and the modern grid.
Series A$720KPi Energy was co-founded by Phil Layton (COO), and the solar technology company has raised capital from retail investors through the equity crowdfunding platform StartEngine.
teaRIOT was founded by husband-and-wife team Laura and Steve Jakobsen in Venice Beach and raised $5M from PearlRock Partners, whose chairman/CEO Brian Kelley (former Keurig Dr Pepper CEO) joined the brand's board.
Series A$695KThe Patch Brand offers vitamin patches designed for easy, effective wellness support, including options for sleep, focus, energy & immunity.
Series A$678KCo-founded in 2019 by Ryan Handel and Scott Leabman in Venice, California, building a bookkeeping and accounting platform specifically for restaurants.