Southern California's
Startup Directory
Series B$84.3MRebuilding healthcare with AI at the core
Pre-Seed$250KBetter, faster tech vendor research
Series D$833.1MWe provide efficient in-space mobility that moves payloads from low Earth orbit to any destination. Our vehicles deliver rapid, reliable access, reducing costs and timelines to make space operations feasible for commercial, government, and scientific missions.
Series C$80.1MOutpace AI-driven attacks. Unify Digital Risk Protection, Human Risk Management, and Email Security to stop digital threats before they scale, empower your teams to lead your defense, and scale your SOC with agentic AI.
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
Series C$25.5MProvivi using modern science to help farmers protect crops in a naturally effective and sustainable way.
Series A$25.5MEnhance, extend or replace your legacy GTM software with affordable enterprise-grade AI-native trade and tariff management software from KYG Trade.
Series B$25.5MMapped turns any building's systems, sensors, and devices into a structured, real-time world model — the data foundation AI agents and applications need to understand and act on the physical world.
858 Therapeutics (its name references San Diego's 858 area code) has raised $110M across Series A and B rounds led by Versant Ventures and Avidity Partners, with participation from NEA and Insight Partners.
Series A$25.0MProper Voltage is the digital bridge that seamlessly links power and product, opening up access to more choices and possibilities.
$25.0M
$25.0MCatalex Network is a private capital-backed partner for elite boutique insurance defense law firms — back office, technology, and growth resources without giving up your culture.