Southern California's
Startup Directory
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Early StageCosight builds always-connected telehealth devices — cellular- and satellite-ready — for video consultations and remote patient monitoring, with real-time translation and integration with FDA-approved medical devices, aimed at hospitals and healthcare providers.
Pre-Seed$250KBetter, faster tech vendor research
Series D$833.1MWe provide efficient in-space mobility that moves payloads from low Earth orbit to any destination. Our vehicles deliver rapid, reliable access, reducing costs and timelines to make space operations feasible for commercial, government, and scientific missions.
Series C$80.1MOutpace AI-driven attacks. Unify Digital Risk Protection, Human Risk Management, and Email Security to stop digital threats before they scale, empower your teams to lead your defense, and scale your SOC with agentic AI.
EXPLORE BY CITY
WHAT SOUTHERN CALIFORNIA BUILDS
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
Series A$695KThe Patch Brand offers vitamin patches designed for easy, effective wellness support, including options for sleep, focus, energy & immunity.
Pre-Seed$695KFounded by attorney Curtis Holdsworth, Bot Mediation built one of the first AI-driven legal mediation platforms, using AI-generated attorney avatars to help mediate injury and dispute cases.
Controlled Delivery Systems is developing a medical device to treat venous insufficiency without thermal energy or a permanent implant.
$688KMiso’s AI-powered kitchen automation platform to improve efficiency, reduce costs, and scale restaurant operations seamlessly.
Series A$678KCo-founded in 2019 by Ryan Handel and Scott Leabman in Venice, California, building a bookkeeping and accounting platform specifically for restaurants.
Seed$675K
Seed$670KFounded by Ariel Trybuch, a fintech data/AI platform built for banks and credit unions.
Series A$667KNano porous silicon particles for controlled release drug delivery for the treatment of ocular diseases such AMD and for application to oncology