Southern California's
Startup Directory
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Early StageCosight builds always-connected telehealth devices — cellular- and satellite-ready — for video consultations and remote patient monitoring, with real-time translation and integration with FDA-approved medical devices, aimed at hospitals and healthcare providers.
Pre-Seed$250KBetter, faster tech vendor research
Series D$833.1MWe provide efficient in-space mobility that moves payloads from low Earth orbit to any destination. Our vehicles deliver rapid, reliable access, reducing costs and timelines to make space operations feasible for commercial, government, and scientific missions.
Series C$80.1MOutpace AI-driven attacks. Unify Digital Risk Protection, Human Risk Management, and Email Security to stop digital threats before they scale, empower your teams to lead your defense, and scale your SOC with agentic AI.
EXPLORE BY CITY
WHAT SOUTHERN CALIFORNIA BUILDS
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
$1.4MTrades publicly on the OTCQB market under the ticker AAPI, unrelated to Apple Inc. despite the similar name and ticker.
Operating as SCATS Gymnastics in Huntington Beach, the nonprofit club has produced 14 U.S. Olympic Team members and over 70 U.S. National Team members.
Series A$1.4MAI-powered travel technology SaaS platform offering end-to-end solutions for Corporates, B2B, and B2C.
Seed$1.3MSMARTER STAFF SCHEDULE MANAGEMENT FOR SKILLED NURSING FACILITIES
Seed$1.3MNext TFX was founded by Eric M.V. Hoek, PhD, a UCLA Samueli School of Engineering professor who invented its ultra-high-pressure filtration technology, alongside co-founder and U.S. Army veteran Pat O'Brien.
$1.3MGood Eat'n is a snack brand founded by NBA legend Chris Paul, and UConn basketball star Paige Bueckers has since become an equity partner in the company.
$1.3MNavega Therapeutics was founded in 2018 by Ana Moreno along with UC San Diego bioengineering professor Prashant Mali, developing gene therapies for chronic pain; it has received a CIRM grant to support its work.
Seed$1.3MOperating as "Beni," this company was founded in 2021 by Sarah Pinner and Celine Mol in Santa Barbara, has raised over $5 million in venture funding, and is a Google for Startups alum.