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Cosight builds always-connected telehealth devices — cellular- and satellite-ready — for video consultations and remote patient monitoring, with real-time translation and integration with FDA-approved medical devices, aimed at hospitals and healthcare providers.

Pre-Seed$250KBetter, faster tech vendor research

We provide efficient in-space mobility that moves payloads from low Earth orbit to any destination. Our vehicles deliver rapid, reliable access, reducing costs and timelines to make space operations feasible for commercial, government, and scientific missions.

Outpace AI-driven attacks. Unify Digital Risk Protection, Human Risk Management, and Email Security to stop digital threats before they scale, empower your teams to lead your defense, and scale your SOC with agentic AI.












































The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.

Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.

Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.

Qualcomm and Broadcom anchor a chip-design cluster spanning the region.

A deep biotech research base and a growing bench of medical device and diagnostics startups.

Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.

Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.

Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.

Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.

Financial technology: payments, banking, investing, and financial infrastructure.

Education technology and learning platforms built across Southern California.

Property technology, construction tech, and real estate services.

Discover Pinhook—Kentucky bourbon and rye whiskey crafted in annual vintages, inspired by horse racing, and blended every year to be the best, not the same
Does business as ScoutUs Pro, a sports-scouting platform; its president, Alex Nehorayan, is based in Sherman Oaks, CA.
A Japanese-American startup founded in 2021 by CEO Tomoya Ogawa (with a Japan-based sister company, Kreation Inc.), it has raised roughly $1.5 million combined from VCs in both Japan and the U.S.

With SolDate, indulge in the velvety richness of almond milk, enhanced with the sweetness and nutrient-rich power of organic dates. Treat your taste buds and nourish your body.
Founded by Ryan Davies in 2021 and led by CEO Byron Elton, the company has raised funds through equity crowdfunding on StartEngine.
Looq.ai builds an AI handheld photogrammetry platform (qCam/qAI/qApp) for 3D land and utility surveying.

Sphere 500 Fossil-Free Index. We track the biggest 500 US companies, minus fossil fuel companies and a few others. Our funds vote our shares for climate action.