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LOS ANGELES · ORANGE COUNTY · SAN DIEGO · INLAND EMPIRE · VENTURA

Southern California's
Startup Directory

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Artificial Intelligence

The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.

104 in our directoryView all →
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Aerospace & Defense

Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.

39 in our directoryView all →
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Entertainment & Gaming Tech

Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.

35 in our directoryView all →
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Semiconductor Hardware

Qualcomm and Broadcom anchor a chip-design cluster spanning the region.

7 in our directoryView all →
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Medical Technology

A deep biotech research base and a growing bench of medical device and diagnostics startups.

291 in our directoryView all →
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B2B

Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.

964 in our directoryView all →
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Industrials

Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.

96 in our directoryView all →
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Consumer

Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.

111 in our directoryView all →
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Healthcare

Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.

248 in our directoryView all →
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Fintech

Financial technology: payments, banking, investing, and financial infrastructure.

22 in our directoryView all →
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Education

Education technology and learning platforms built across Southern California.

3 in our directoryView all →
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Real Estate & Construction

Property technology, construction tech, and real estate services.

15 in our directoryView all →
View all funded companies →
$17.0M
Palomino Laboratories Inc.
Goleta, CA · Founded 2022

GaN semiconductor company co-founded by CEO Jeffrey Shealy and UC Santa Barbara materials scientist Dr. Steven DenBaars; raised $15M and is acquiring Vega Links.

B2B
Series A$17.0M
AnySignal, Inc.
El Segundo, CA · Founded 2022

The integrated platform for the electromagnetic spectrum. One platform for RF design, production, and network operations.

Series AB2B
Series B$16.8M
LiveOne, Inc.
Beverly Hills, CA

LiveOne (NASDAQ:LVO) is a global digital media company dedicated to music and live entertainment. LiveOne powered by Slacker Radio is your home for music, podcasts, and more featuring Dolly Parton: DNA, Weezer: The Count Up, Album of the Week, The Magnificent Others with Billy Corgan, Hip Hop/R&B Hits

Series BB2B
$16.7M
Dare Bioscience, Inc.
San Diego, CA

At Daré Bioscience, women’s health is our mission. From clinical trials and non-hormonal contraception to therapies for menopause and vaginal dryness to vaginal health, our research is evidence-based and built exclusively for women.

Healthcare
Series B$16.7M
Fictions, Inc.
Los Angeles, CA · Founded 2024

Fictions is a game developer and publisher established in 2025. Current titles include LEGO Party and Beast of Reincarnation.

Series BB2B
Series A$16.6M
Nuon Inc.
Beverly Hills, CA · ~11-50 employees
Series AB2B
Series A$16.5M
Systm Foods Inc.
Newport Beach, CA · Founded 2022

Newport Beach-based beverage holding company built via a roll-up strategy by GroundForce Capital; it is the parent of recognizable brands REBBL, Chameleon Cold-Brew, and Humm Kombucha.

Series AB2B
Series A$16.5M
Gamefam, Inc.
Los Angeles, CA · Founded 2019

Gamefam creates immersive gaming experiences for brands on Roblox and Fortnite, engaging Gen Z & Alpha audiences through innovative campaigns and full-scale amplification programs.

Series AB2B