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LOS ANGELES · ORANGE COUNTY · SAN DIEGO · INLAND EMPIRE · VENTURA

Southern California's
Startup Directory

A futuristic humanoid robot in an indoor Tokyo setting, showcasing modern technology.

Artificial Intelligence

The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.

104 in our directoryView all →
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Aerospace & Defense

Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.

39 in our directoryView all →
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Entertainment & Gaming Tech

Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.

35 in our directoryView all →
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Semiconductor Hardware

Qualcomm and Broadcom anchor a chip-design cluster spanning the region.

7 in our directoryView all →
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Medical Technology

A deep biotech research base and a growing bench of medical device and diagnostics startups.

291 in our directoryView all →
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B2B

Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.

964 in our directoryView all →
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Industrials

Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.

96 in our directoryView all →
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Consumer

Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.

111 in our directoryView all →
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Healthcare

Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.

248 in our directoryView all →
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Fintech

Financial technology: payments, banking, investing, and financial infrastructure.

22 in our directoryView all →
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Education

Education technology and learning platforms built across Southern California.

3 in our directoryView all →
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Real Estate & Construction

Property technology, construction tech, and real estate services.

15 in our directoryView all →
View as table →
Seed$575K
Vetmab Biosciences, Inc.
San Diego, CA · Founded 2022

Developing Life-Changing Therapeutics For Our Pets Monoclonal antibodies (mAbs) for modern veterinary practices Developing Life-Changing Therapeutics For Our Pets Monoclonal... Read More

SeedHealthcare
Seed$568K
Scout Distribution AZ, LLC
San Diego, CA · Founded 2022
SeedB2B
Seed$525K
Purple Magpie Mandarin LLC
Los Angeles, CA · Founded 2022
SeedB2B
Seed$524K
Electric Avenue Software, Inc.
Solana Beach, CA

Electric Avenue is a smart electric vehicle charging and energy management provider for commercial and residential charging needs. Compatible with all North American EVs. Level 2 and DC Fast Charging. Charge Management Software. Dynamic Load Management. iOS and Android App. Open-Source. OCPP. It's time to go electric!

SeedB2B
Seed$520K
Orbital Operations Inc
Huntington Beach, CA · Founded 2024

Founded by aerospace veterans Ben Schleuniger and Ross Doherty (formerly of NASA, SpaceX, and Relativity Space) and backed through Y Combinator's Winter 2025 batch; investors include Batch Ventures, DTX Ventures, and Mercury co-founder Immad Akhund.

SeedB2B
Seed$500K
Expond Inc.
Santa Barbara, CA · Founded 2021

Explore private in-person and group experiences: Yoga, personal training, kayaking, hiking, surfing, meditation and so much more in Santa Barbara, California!

SeedB2B
Seed$500K
Primary Club, Inc.
Los Angeles, CA
SeedB2B
Seed$500K
Cassette, Inc.
Los Angeles, CA

Cassette Modular Homes are move-in ready in as little as 6 months.

SeedReal Estate and Construction