Southern California's
Startup Directory
Series B$84.3MRebuilding healthcare with AI at the core
Pre-Seed$250KBetter, faster tech vendor research
Series D$833.1MWe provide efficient in-space mobility that moves payloads from low Earth orbit to any destination. Our vehicles deliver rapid, reliable access, reducing costs and timelines to make space operations feasible for commercial, government, and scientific missions.
Series C$80.1MOutpace AI-driven attacks. Unify Digital Risk Protection, Human Risk Management, and Email Security to stop digital threats before they scale, empower your teams to lead your defense, and scale your SOC with agentic AI.
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
Seed$670KFounded by Ariel Trybuch, a fintech data/AI platform built for banks and credit unions.
Seed$658KGrinData micro markets software leverages best-in-class high-frequency trading and machine learning to deliver reliable odds pricing on the most markets. Brought to you by Grin Gaming.
Seed$655KYouAttest offers cloud based identity auditing solutions and management We Securely manage user access and ensure compliance with ease Get started today!
Seed$650KStorygize was founded in 2015 by David Osman and has raised roughly $10 million in total funding for its programmatic advertising platform, headquartered in Santa Barbara.
Seed$581KAzora Therapeutics, an LA biopharma founded in 2019 by Matt Davidson and Julie Saiki, was acquired by Adial Pharmaceuticals in 2026 for up to $64 million.
Seed$578KVirtual Showroom Design operates as WeVisu, an AI-powered digital showroom platform for contractors and interior designers, founded by Betsalel Medioni and Moshe Fishbain.
Seed$578K