Southern California's
Startup Directory
Series B$84.3MRebuilding healthcare with AI at the core
Pre-Seed$250KBetter, faster tech vendor research
Series D$833.1MWe provide efficient in-space mobility that moves payloads from low Earth orbit to any destination. Our vehicles deliver rapid, reliable access, reducing costs and timelines to make space operations feasible for commercial, government, and scientific missions.
Series C$80.1MOutpace AI-driven attacks. Unify Digital Risk Protection, Human Risk Management, and Email Security to stop digital threats before they scale, empower your teams to lead your defense, and scale your SOC with agentic AI.
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
Series A$1.5MFounders First Capital Partners - Revenue-Based Funding & Business Advisory
Series A$1.5MSphere 500 Fossil-Free Index. We track the biggest 500 US companies, minus fossil fuel companies and a few others. Our funds vote our shares for climate action.
Series A$1.5MDiscover Allevion Therapeutics’ Allevx™ Smart-Band, a wearable device designed to reduce movement-related disorders due to Essential Tremor.
Series A$1.4MAI-powered travel technology SaaS platform offering end-to-end solutions for Corporates, B2B, and B2C.
Series A$1.2MHalla was founded in 2016 by Spencer Price, Henry Michaelson, and Gabriel Nipote and built an AI 'taste intelligence' engine to predict grocery purchases; it raised a $4.5M Series A1 in 2021.
Series A$1.2MWe build high-completion learning programs using educational creators. Financial literacy, career skills, and benefits education that employees actually finish.
Series A$1.2MSan Diego cancer-drug-discovery company co-founded in 2020 by Pilgrim Jackson (13 years at Celgene) and Afshin Mahmoudi; backers include CONNECT San Diego.