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LOS ANGELES · ORANGE COUNTY · SAN DIEGO · INLAND EMPIRE · VENTURA

Southern California's
Startup Directory

330
companies
$1.11B
raised across all listings
iIncludes SEC Form D filings from the last 3 years, plus all-time totals for companies sourced from YC and news coverage. More on /about →
44
cities
SPOTLIGHT
View all funded companies →
Series B$84.3M
Akido Labs
Los Angeles, CA · Founded 2014 · 1000 employees

Rebuilding healthcare with AI at the core

Y CombinatorSeries BHealthcare
Pre-Seed$250K
Taloflow
Los Angeles, CA · Founded 2021 · 4 employees

Better, faster tech vendor research

Y CombinatorPre-SeedB2B
Series D$833.1M
Impulse Space, Inc.
El Segundo, CA · Founded 2021 · ~201-500 employees

We provide efficient in-space mobility that moves payloads from low Earth orbit to any destination. Our vehicles deliver rapid, reliable access, reducing costs and timelines to make space operations feasible for commercial, government, and scientific missions.

Series DB2B
Series C$80.1M
Doppel Inc.
Covina, CA · Founded 2022 · ~201-500 employees

Outpace AI-driven attacks. Unify Digital Risk Protection, Human Risk Management, and Email Security to stop digital threats before they scale, empower your teams to lead your defense, and scale your SOC with agentic AI.

Series CB2B
EXPLORE BY CITY
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Downtown Los Angeles skyline
Los Angeles
394 companies
San Diego skyline
San Diego
231 companies
Aerial view looking east toward Santa Ana and Irvine, California
Irvine
98 companies
Aerial view of the Santa Monica Pier
Santa Monica
75 companies
Collage of scenes from Carlsbad, California
Carlsbad
44 companies
Aerial view of El Segundo, California
El Segundo
43 companies
Aerial photo of Newport Beach, California
Newport Beach
38 companies
Street scene in Beverly Hills showing iconic buildings, busy pedestrian areas, and lively urban atmosphere.
Beverly Hills
37 companies
A scenic street view in Santa Barbara on a sunny day with flags and mountains in the background.
Santa Barbara
34 companies
A beautiful twilight aerial view of Sacramento's urban skyline with historic Old Sacramento in foreground.
Covina
28 companies
Aerial view of Santa Monica city skyline on a bright day with clear blue skies.
Culver City
26 companies
Aerial shot of La Jolla Cove in San Diego, California, showcasing coastal cliffs, cityscape, and foggy atmosphere.
La Jolla
26 companies
A stunning aerial view of the Venice Canals district in Los Angeles on a sunny day.
Venice
24 companies
A grandiose hotel building with classic architecture located in Pasadena, California, under a clear blue sky.
Pasadena
24 companies
Aerial view of a town with lush hills and clear sky, capturing urban and natural beauty.
Woodland Hills
24 companies
View of the Hollywood Sign with palm trees and city scene in West Hollywood, California.
West Hollywood
22 companies
A serene sunset over a bustling harbor with bridges, cranes and tranquil waters.
Long Beach
21 companies
Sunny day street scene with the iconic Encinitas sign and palm trees in California.
Encinitas
18 companies
Aerial view of a coastal city at twilight with shoreline and cityscape.
Goleta
18 companies
Explore Huntington Beach's beautiful neighborhood and coastline in this vibrant aerial shot.
Huntington Beach
18 companies
A stunning aerial view of the Manhattan Beach Pier extending over the ocean with cityscape in the background.
Manhattan Beach
16 companies
Aerial photograph showcasing a suburban neighborhood in Costa Mesa, CA, with neatly arranged houses and streets.
Costa Mesa
14 companies
A beautiful twilight aerial view of Sacramento's urban skyline with historic Old Sacramento in foreground.
Encino
14 companies
Explore Huntington Beach's beautiful neighborhood and coastline in this vibrant aerial shot.
Solana Beach
14 companies
Cityscape featuring palm trees and modern buildings under a bright sunny sky.
Anaheim
13 companies
Aerial view of Santa Monica city skyline on a bright day with clear blue skies.
Santa Ana
13 companies
Street signs with Spanish-style architecture, depicting direction and local street names on a sunny day.
Del Mar
11 companies
Torrance City Hall
Torrance
11 companies
Stunning aerial view of Glendale, showcasing downtown's skyline on a bright day.
Glendale
11 companies
Explore the bustling Marina del Rey Harbor with yachts and cityscape in the background.
Marina Del Rey
11 companies
Busy Los Angeles highway scene in grayscale, featuring vehicles and road signs.
Sherman Oaks
10 companies
Busy Los Angeles highway scene in grayscale, featuring vehicles and road signs.
Thousand Oaks
10 companies
Families stroll along the colorful Redondo Beach Pier under a clear sky in California.
Redondo Beach
8 companies
Colorful neon art studio sign illuminated at twilight in Paso Robles, California.
Studio City
7 companies
Vibrant sunset view of Burbank highway, palm trees, and light trails creating a dynamic urban scene.
Burbank
7 companies
A stunning aerial view of Ventura, California capturing the coastal town and ocean on a sunny day.
Ventura
6 companies
A stunning view of Sacramento's skyline at sunset, with colorful clouds and prominent buildings.
Chula Vista
5 companies
Scenic aerial cityscape of London, Ontario with modern architecture and busy streets.
Ontario
5 companies
Calm waves and a vibrant sky at sunset on Hermosa Beach, CA.
Hermosa Beach
5 companies
A stunning panorama of a cityscape with dramatic sunbeams piercing through overcast clouds above green hills.
Calabasas
5 companies
Coastal street view with modern architecture during sunset, creating a warm and inviting atmosphere.
Oceanside
4 companies
Scenic view of modern hillside homes with lush greenery and blue sky backdrop.
Laguna Beach
4 companies
Vibrant orange tree with street signs on University Avenue, Davis, CA.
Orange
3 companies
Parked ambulance under bright sky in Palm Springs with towering palm trees and mountain view.
Palm Springs
3 companies
Explore a stunning aerial shot of Downtown Riverside, CA, featuring a historic cathedral.
Riverside
2 companies
Griffith Observatory with Los Angeles skyline in the background during a hazy day.
Hollywood
2 companies
Aerial photograph showcasing the iconic Tustin hangars in California, USA.
Tustin
2 companies
Stunning aerial view of Riverside cityscape, with mountains in the background under a twilight sky.
Claremont
2 companies
A winter aerial view of snow-capped mountains with San Bernardino cityscape in the foreground, California.
Simi Valley
1 company
A breathtaking aerial shot of modern urban sprawl in Los Angeles, showcasing diverse architecture.
Playa Vista
1 company
Contemporary upscale residential buildings in Temecula, CA, captured at sunset.
Temecula
1 company
WHAT SOUTHERN CALIFORNIA BUILDS
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A futuristic humanoid robot in an indoor Tokyo setting, showcasing modern technology.

Artificial Intelligence

The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.

Shield AI IncIambic Therapeutics, Inc.RENOVARO INC.
104 in our directoryView all →
Dramatic view of rocket boosters against a bright blue sky, showcasing aerospace technology.

Aerospace & Defense

Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.

HadrianShield AI IncCastelion
39 in our directoryView all →
A behind-the-scenes look at a filming crew setting up a scene indoors with lighting equipment.

Entertainment & Gaming Tech

Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.

Spotter, Inc.WONDER PROJECT, INC.Titan Content, Inc.
35 in our directoryView all →
Detailed view of a motherboard with visible microchips and circuits.

Semiconductor Hardware

Qualcomm and Broadcom anchor a chip-design cluster spanning the region.

Sift Stack, Inc.FOCUS UNIVERSAL INC.Airhart Aeronautics, Inc.
7 in our directoryView all →
A healthcare worker operates a modern infusion pump in a hospital setting, ensuring precise medication delivery.

Medical Technology

A deep biotech research base and a growing bench of medical device and diagnostics startups.

Avenzo Therapeutics, Inc.ImmunityBio, Inc.Mirador Therapeutics, Inc.
291 in our directoryView all →
Laptop on office desk with a city skyline through a large window, offering a modern workspace view.

B2B

Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.

Shield AI IncMetropolis Technologies, Inc.Skims Body, Inc.
964 in our directoryView all →
Modern industrial machine in operation in a manufacturing facility showcasing advanced technology.

Industrials

Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.

Radiant Industries, IncNewlight Technologies, Inc.Advanced Manufacturing Co of America, Inc.
96 in our directoryView all →
A woman helps a man choose a shirt in a modern clothing store.

Consumer

Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.

HWOOD GROUP, LLCOne Source To Market, LLCSauce Ventures, LLC
111 in our directoryView all →
High-tech laboratory equipment with multiple vials in a scientific research facility.

Healthcare

Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.

Avenzo Therapeutics, Inc.ImmunityBio, Inc.Mirador Therapeutics, Inc.
248 in our directoryView all →
Bitcoin coin with financial data, credit cards, and currency on a desk.

Fintech

Financial technology: payments, banking, investing, and financial infrastructure.

FOUNDERS FIRST CHANGE CATALYST, LLCBaseline Risk Partners, LLCCARDIFF, INC.
22 in our directoryView all →
A group of students attending a lecture wearing school uniforms, focused and attentive.

Education

Education technology and learning platforms built across Southern California.

JumpcutRocketLitPanorama Education
3 in our directoryView all →
A construction worker operating a concrete mixer at an active building site, emphasizing safety gear.

Real Estate & Construction

Property technology, construction tech, and real estate services.

Strata Millenia, LLCMaui Business Park, LLCAstera
15 in our directoryView all →
All stagesPre-Seed (44)Seed (330)Series A (260)Series B (124)Series C (40)Series D (26)Series E (3)Series F (6)Series G (1)
View as table →
Seed$1.5M
Global Scouting Database, Inc.
Sherman Oaks, CA · Founded 2021

Does business as ScoutUs Pro, a sports-scouting platform; its president, Alex Nehorayan, is based in Sherman Oaks, CA.

SeedB2B
Seed$1.5M
Great Organic, Inc.
Glendale, CA · Founded 2022

With SolDate, indulge in the velvety richness of almond milk, enhanced with the sweetness and nutrient-rich power of organic dates. Treat your taste buds and nourish your body.

SeedB2B
Seed$1.5M
Talisman Global, LLC
Los Angeles, CA · Founded 2023
SeedB2B
Seed$1.5M
CancerVAX, Inc.
Santa Barbara, CA · Founded 2021

Founded by Ryan Davies in 2021 and led by CEO Byron Elton, the company has raised funds through equity crowdfunding on StartEngine.

SeedHealthcare
Seed$1.5M
Limar AI Inc.
San Diego, CA · Founded 2021
SeedB2B
Seed$1.4M
Shelter DP, LLC
Santa Barbara, CA · Founded 2025

Shelter Products Inc. specializes in delivering high-quality building materials for large-scale construction projects nationwide. Discover how we can help you.

SeedB2B
Seed$1.4M
TPT GLOBAL TECH, INC.
San Diego, CA

TPT Global Tech is a technology holding company with an emphasis on Media Content, Medical Technology and Telecommunications.

SeedB2B
Seed$1.3M
Dropstat, Inc.
Los Angeles, CA

SMARTER STAFF SCHEDULE MANAGEMENT FOR SKILLED NURSING FACILITIES

SeedB2B