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LOS ANGELES · ORANGE COUNTY · SAN DIEGO · INLAND EMPIRE · VENTURA

Southern California's
Tech
Startup Directory

A futuristic humanoid robot in an indoor Tokyo setting, showcasing modern technology.

Artificial Intelligence

The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.

104 in our directoryView all →
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Aerospace & Defense

Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.

39 in our directoryView all →
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Entertainment & Gaming Tech

Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.

35 in our directoryView all →
Detailed view of a motherboard with visible microchips and circuits.

Semiconductor Hardware

Qualcomm and Broadcom anchor a chip-design cluster spanning the region.

7 in our directoryView all →
A healthcare worker operates a modern infusion pump in a hospital setting, ensuring precise medication delivery.

Medical Technology

A deep biotech research base and a growing bench of medical device and diagnostics startups.

291 in our directoryView all →
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B2B

Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.

964 in our directoryView all →
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Industrials

Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.

96 in our directoryView all →
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Consumer

Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.

111 in our directoryView all →
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Healthcare

Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.

248 in our directoryView all →
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Fintech

Financial technology: payments, banking, investing, and financial infrastructure.

22 in our directoryView all →
A group of students attending a lecture wearing school uniforms, focused and attentive.

Education

Education technology and learning platforms built across Southern California.

3 in our directoryView all →
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Real Estate & Construction

Property technology, construction tech, and real estate services.

15 in our directoryView all →
View as table →
Series A$4.0M
F42 Corp
Newport Beach, CA · Founded 2026
Series AB2B
Series A$3.9M
Trinary Solar Group VIII LLC
Long Beach, CA · Founded 2025

Providing solar installations to commercial, industrial, and agricultural facilities. Trinary Energy uses a power purchase agreement to provide renewable energy at no up-front cost to you.

Series AIndustrials
Series A$3.8M
LumiTerra, Inc.
Los Angeles, CA · Founded 2021

Lumiterra is a brand-new, multiplayer, open-world survival crafting game where you can battle, farm with your friends or mysterious collected creatures in a vast world!

Series AIndustrials
Series A$3.8M
Thorwear Inc
San Diego, CA · Founded 2019

Also known as Elevate Dynamics; co-founder Daniel Magy previously founded Citadel Defense Company, a counter-drone defense firm that was later acquired by Blue Halo.

Series AB2B
Series A$3.7M
Virgo Surgical Video Solutions, Inc.
Carlsbad, CA

Virgo builds frontier AI models to solve diseases mediated by the gut. Our flagship model, EndoDINO, was trained on the largest GI endoscopy dataset.

Series AHealthcare
Series A$3.7M
NewPayHealth, Inc.
Los Angeles, CA · Founded 2023
Series AB2B
Series A$3.6M
ProCode Inc.
Los Angeles, CA · Founded 2024 · ~51-200 employees

Operating as Procode AI, the company was founded in 2024 by Jeff Cripe, Dr. Kameron Rezzadeh, and James Baez-Silva to build an AI-powered roll-up of revenue cycle management companies; backed by Story Ventures and Health Velocity Capital.

Series AB2B
Series A$3.6M
Project Obelisk, Inc.
Glendale, CA · Founded 2025
Series AB2B