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LOS ANGELES · ORANGE COUNTY · SAN DIEGO · INLAND EMPIRE · VENTURA

Southern California's
Tech
Startup Directory

Showcasing Southern California's innovation, one startup at a time. Every funded and bootstrapped company, from seed round to first dollar of revenue, tracked as it happens.

295
companies
$3.82B
raised across all listings
39
cities

Includes SEC Form D filings from the last 3 years, plus all-time totals for companies sourced from YC and news coverage.

A futuristic humanoid robot in an indoor Tokyo setting, showcasing modern technology.

Artificial Intelligence

The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.

105 in our directoryView all →
Dramatic view of rocket boosters against a bright blue sky, showcasing aerospace technology.

Aerospace & Defense

Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.

39 in our directoryView all →
A behind-the-scenes look at a filming crew setting up a scene indoors with lighting equipment.

Entertainment & Gaming Tech

Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.

35 in our directoryView all →
Detailed view of a motherboard with visible microchips and circuits.

Semiconductor Hardware

Qualcomm and Broadcom anchor a chip-design cluster spanning the region.

7 in our directoryView all →
A healthcare worker operates a modern infusion pump in a hospital setting, ensuring precise medication delivery.

Medical Technology

A deep biotech research base and a growing bench of medical device and diagnostics startups.

291 in our directoryView all →
Laptop on office desk with a city skyline through a large window, offering a modern workspace view.

B2B

Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.

964 in our directoryView all →
Modern industrial machine in operation in a manufacturing facility showcasing advanced technology.

Industrials

Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.

97 in our directoryView all →
A woman helps a man choose a shirt in a modern clothing store.

Consumer

Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.

111 in our directoryView all →
High-tech laboratory equipment with multiple vials in a scientific research facility.

Healthcare

Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.

248 in our directoryView all →
Bitcoin coin with financial data, credit cards, and currency on a desk.

Fintech

Financial technology: payments, banking, investing, and financial infrastructure.

22 in our directoryView all →
A group of students attending a lecture wearing school uniforms, focused and attentive.

Education

Education technology and learning platforms built across Southern California.

3 in our directoryView all →
A construction worker operating a concrete mixer at an active building site, emphasizing safety gear.

Real Estate & Construction

Property technology, construction tech, and real estate services.

15 in our directoryView all →
Series A$74.1M
Alpha Design AI, Inc.
Goleta, CA · Founded 2024

Does business as ChipAgents, an agentic AI chip-design platform founded by CEO William Wang; has raised $134M in funding from investors including Bessemer Venture Partners and Matter Venture Partners.

Series AB2B
Series A$73.6M
Monarch Quantum, Inc.
San Diego, CA · Founded 2025

We’re an integrated photonics company in California building the light engines that power the next era of quantum technology — from advanced computing to precision sensing.

Series AIndustrials
Series A$72.8M
Kate Therapeutics Inc.
San Diego, CA · Founded 2020

Gene therapy company that emerged from stealth in June 2023 with a $51M Series A co-led by Westlake Village BioPartners, developing AAV-based genetic medicines for muscle and heart disease.

Series AHealthcare
Series A$63.3M
CeleCor Therapeutics, Inc.
Del Mar, CA

Co-founded by biomedical engineer Robert S. Hillman, PhD; developing devices/therapies to get STEMI heart-attack patients to treatment with open coronary arteries, and has raised $58.4M.

Series AHealthcare
Series A$60.8M
VST BIO Corp
San Diego, CA

San Diego biologics company led by CEO Krisztina Zsebo, PhD, developing vascular biologic therapies for ischemic stroke and acute cardiovascular disease.

Series AHealthcare
Series A$60.3M
Kudos Technologies, Inc.
Woodland Hills, CA · Founded 2021

Kudos® is the recognition and rewards platform designed to fit your unique workplace culture.

Series AB2B
Series A$55.5M
Big Shot Pictures Inc.
Los Angeles, CA · Founded 2025

Big Shot Pictures is a next-generation studio building global franchises, founded by Brian Robbins.

Series AB2B
Series A$55.0M
Praesidium Holdings, Inc.
Marina Del Rey, CA · Founded 2024

Praesidium applies an owner-oriented, private equity approach to investing in the public markets. Praesidium manages long-term capital for a select group of institutional investors.

Series AB2B