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LOS ANGELES · ORANGE COUNTY · SAN DIEGO · INLAND EMPIRE · VENTURA

Southern California's
Tech
Startup Directory

Showcasing Southern California's innovation, one startup at a time. Every funded and bootstrapped company, from seed round to first dollar of revenue, tracked as it happens.

295
companies
$3.82B
raised across all listings
39
cities

Includes SEC Form D filings from the last 3 years, plus all-time totals for companies sourced from YC and news coverage.

A futuristic humanoid robot in an indoor Tokyo setting, showcasing modern technology.

Artificial Intelligence

The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.

105 in our directoryView all →
Dramatic view of rocket boosters against a bright blue sky, showcasing aerospace technology.

Aerospace & Defense

Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.

39 in our directoryView all →
A behind-the-scenes look at a filming crew setting up a scene indoors with lighting equipment.

Entertainment & Gaming Tech

Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.

35 in our directoryView all →
Detailed view of a motherboard with visible microchips and circuits.

Semiconductor Hardware

Qualcomm and Broadcom anchor a chip-design cluster spanning the region.

7 in our directoryView all →
A healthcare worker operates a modern infusion pump in a hospital setting, ensuring precise medication delivery.

Medical Technology

A deep biotech research base and a growing bench of medical device and diagnostics startups.

291 in our directoryView all →
Laptop on office desk with a city skyline through a large window, offering a modern workspace view.

B2B

Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.

964 in our directoryView all →
Modern industrial machine in operation in a manufacturing facility showcasing advanced technology.

Industrials

Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.

97 in our directoryView all →
A woman helps a man choose a shirt in a modern clothing store.

Consumer

Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.

111 in our directoryView all →
High-tech laboratory equipment with multiple vials in a scientific research facility.

Healthcare

Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.

248 in our directoryView all →
Bitcoin coin with financial data, credit cards, and currency on a desk.

Fintech

Financial technology: payments, banking, investing, and financial infrastructure.

22 in our directoryView all →
A group of students attending a lecture wearing school uniforms, focused and attentive.

Education

Education technology and learning platforms built across Southern California.

3 in our directoryView all →
A construction worker operating a concrete mixer at an active building site, emphasizing safety gear.

Real Estate & Construction

Property technology, construction tech, and real estate services.

15 in our directoryView all →
View as table →
Series A$16.5M
Systm Foods Inc.
Newport Beach, CA · Founded 2022

Newport Beach-based beverage holding company built via a roll-up strategy by GroundForce Capital; it is the parent of recognizable brands REBBL, Chameleon Cold-Brew, and Humm Kombucha.

Series AB2B
Series A$16.5M
Gamefam, Inc.
Los Angeles, CA · Founded 2019

Gamefam creates immersive gaming experiences for brands on Roblox and Fortnite, engaging Gen Z & Alpha audiences through innovative campaigns and full-scale amplification programs.

Series AB2B
Series A$16.4M
Accrual, Inc.
Beverly Hills, CA · Founded 2024

Accrual transforms accounting firms with AI. Automate tax returns, streamline client data collection, and scale your practice with intelligent workflows.

Series AB2B
Series A$16.3M
Tempo Therapeutics, Inc.
San Diego, CA

Tempo Therapeutics is a biotechnology and tissue engineering company based out of San Diego, CA specializing in speeding up patient recovery.

Series AHealthcare
Series A$16.2M
TAD HEALTH INC.
Newport Beach, CA · Founded 2021

TadHealth is the leading school-based EHR platform designed for K‑12 schools, empowering mental health professionals with intuitive tools to manage care, streamline operations, and improve student outcomes.

Series AB2B
Series A$15.7M
Model Medicines, Inc.
La Jolla, CA · Founded 2019

Model Medicines engineers first-in-class small molecules against biological choke points, using AI to advance pipeline-in-a-pill therapeutics across high-impact diseases.

Series AHealthcare
Series A$15.6M
Handl Health, Inc.
Culver City, CA · Founded 2022

Price transparency and plan design tools for self-funded health plan comparisons and enhanced employee benefits strategies.

Series AHealthcare
Series A$15.6M
Huupe Inc.
Irvine, CA · Founded 2020

huupe brings you the world’s first smart basketball hoop, providing NBA level workouts, on-demand training, live coaching, data tracking and more.

Series AB2B