Southern California's
Tech
Startup Directory
Showcasing Southern California's innovation, one startup at a time. Every funded and bootstrapped company, from seed round to first dollar of revenue, tracked as it happens.
Includes SEC Form D filings from the last 3 years, plus all-time totals for companies sourced from YC and news coverage.
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
Series A$48.2MDiscover how Immunis, a private biotechnology company is developing new secretome products for the treatment of age-related immune dysfunction
Oncocyte is a publicly traded diagnostics company (Nasdaq: OCX) that later renamed itself Insight Molecular Diagnostics and relocated its headquarters to Nashville.
Series B$47.6MRobotics Startup for Space Development
SRT Therapeutics was founded in 2024 by former leaders of Prometheus Biosciences, including President & CEO Lauren Otsuki, and launched with roughly $47M in funding.
$42.0MRestora Medical was founded by Dr. Quan Ni, who previously co-founded Inspire Medical Systems (Nasdaq: INSP).
Series C$41.2MMovandi was founded by siblings Maryam and Reza Rofougaran, recognized pioneers in RF/SoC design from their time at Broadcom, with backers including Sierra Ventures and Celesta Capital.