Southern California's
Tech
Startup Directory
Showcasing Southern California's innovation, one startup at a time. Every funded and bootstrapped company, from seed round to first dollar of revenue, tracked as it happens.
Includes SEC Form D filings from the last 3 years, plus all-time totals for companies sourced from YC and news coverage.
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
Series A$50.0MCounterpart is the first Agentic Insurance™ system specializing in management and professional liability insurance.
Strata Millenia is tied to Strata Equity Group, which partnered with Ryan Companies to develop a 278-unit multifamily community within the Millenia master-planned district in Chula Vista.
Series B$50.0MDisrupt Pain Without Opioids. While other treatments dull pain, Latigo’s solutions target the source of pain before it reaches the central nervous system. The result is healing without dependence, and relief that can help restore quality of life.
Series E$50.0MEledon Pharmaceuticals was co-founded and is led by CEO David-Alexandre Gros, a physician and serial biotech entrepreneur, with investors including BVF Partners, RA Capital Management, and Blue Owl Capital.
Series B$50.0MTS Conductor's AECC technology doubles or triples capacity while cutting costs. Safe, easy installation with industry-leading performance.
Series C$49.0MSteno is a legal tech company offering court reporting services and a software platform to manage depositions, transcripts, and high-stakes litigation, aiming to make the process more efficient.
Series A$48.5MAffinity Biosensors’ LifeScale platform delivers rapid, high-throughput phenotypic antimicrobial susceptibility testing in under four hours, empowering clinical labs to make timely antibiotic decisions and combat drug-resistant infections.