Southern California's
Tech
Startup Directory
Showcasing Southern California's innovation, one startup at a time. Every funded and bootstrapped company, from seed round to first dollar of revenue, tracked as it happens.
Includes SEC Form D filings from the last 3 years, plus all-time totals for companies sourced from YC and news coverage.
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
TRC 2004 was co-founded by Third Rock Ventures and Two River, the same investor group behind Kite Pharma (sold to Gilead for roughly $11.9B), and later emerged publicly as Candid Therapeutics with a $370M capital raise.
Series C$90.0MBright Peak Therapeutics was founded in 2017 by Vijaya Pattabiraman and Jeffrey Bode and raised a $90M Series C backed by Versant Ventures, Fidelity, RA Capital, and the Qatar Investment Authority.
Series B$85.0MAardvark Therapeutics is a clinical-stage biopharmaceutical company developing novel, small-molecule therapies designed to inhibit hunger and treat metabolic
Series B$85.0MProactive health memberships combining Whole Body MRI, advanced blood biomarker testing, and ongoing clinical guidance—designed to help you track your health year over year.
Series B$84.3MRebuilding healthcare with AI at the core
Series C$84.2MBloom Nutrition provides health and wellness supplements for women, with high quality ingredients to support energy, gut health and hormone balance. Shop our greens, beauty and fitness supplements.
Series A$83.3MAstroForge is a commercial space startup focused on asteroid mining and the extraction of platinum group metals and other critical minerals. Explore our deep space missions and discover how we’re shaping the future of space resources and off-world mining.
Series A$83.0MFirestorm Labs - Democratize the fight with radically-affordable, mission-adaptable power for air, land, and sea.