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LOS ANGELES · ORANGE COUNTY · SAN DIEGO · INLAND EMPIRE · VENTURA

Southern California's
Startup Directory

Every VC-backed and bootstrapped startup founded in Los Angeles, Orange County, San Diego, the Inland Empire, and Ventura — company profiles, funding rounds, and the investors and accelerators actually writing checks in the region, not a national list with a few SoCal names mixed in.

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Seed$10.0M
Andrenam
Hawthorne, CA · 6 employees

AndrenaM builds AI-driven autonomous maritime systems for defense; founded by ex-SpaceX engineers.

SeedDefense Technology
Manifest Space hero photo
Manifest Space
Los Angeles, CA

Manifest Space provides infrastructure for persistent spacecraft identity, position, and visibility throughout the mission lifecycle to enable coordinated operations across the orbital ecosystem.

Defense Technology
Landline hero photo
Landline
Hawthorne, CA

Landline builds infrastructure that decentralizes the airport by providing remote screening checkpoints for commercial aviation and premium ground transportation integrated into airline reservation systems.

Defense Technology
Aviation Capital Group
Newport Beach, CA

Aviation Capital Group creates innovative ways to acquire and finance fuel-efficient commercial aircraft to help the aviation industry transition to a sustainable future.

Defense Technology
K2 Space hero photo
K2 Space
Torrance, CA

K2 Space builds high-power satellite platforms, specifically Mega Class satellites, that deliver significant power to payloads, mass on orbit, and resilience across various orbital environments.

Defense Technology
The Adversarial Company hero photo
The Adversarial Company
North Hollywood, CA

The Adversarial Company builds AI-native denial and deception systems, including WRAITH, AI software for generating and evaluating camouflage for machine-observed environments.

Defense Technology
Northwood Space
Torrance, CA

Northwood Space is building a global ground network for space communications by providing hardware that deploys in hours, software that orchestrates contacts, and a network that moves data from spacecraft to customer.

Defense Technology

Artificial Intelligence

The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.

255 in our directoryView all →

Aerospace & Defense

Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.

72 in our directoryView all →

Entertainment & Gaming Tech

Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.

106 in our directoryView all →

Semiconductor Hardware

Qualcomm and Broadcom anchor a chip-design cluster spanning the region.

28 in our directoryView all →

Pharmaceutical & Biopharma

Drug developers and biopharma platforms, concentrated in San Diego's Torrey Pines corridor and the LA biotech cluster. Searched as "pharmaceutical companies in San Diego / Orange County" more than any other industry phrase in our Search Console data.

122 in our directoryView all →

Biotechnology & Life Sciences

The life-science research base behind San Diego's and Los Angeles's biotech reputations: platforms, tools, diagnostics and therapeutics spun out of UCSD, Scripps, Caltech and UCLA.

193 in our directoryView all →

Software & SaaS

Software companies across the region, from Irvine's enterprise SaaS bench to Santa Monica's consumer apps: the broadest category here after AI, and the one people search for by city.

409 in our directoryView all →

Medical Technology

A deep biotech research base and a growing bench of medical device and diagnostics startups.

477 in our directoryView all →

B2B

Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.

1030 in our directoryView all →

Industrials

Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.

114 in our directoryView all →

Consumer

Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.

164 in our directoryView all →

Healthcare

Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.

283 in our directoryView all →

Fintech

Financial technology: payments, banking, investing, and financial infrastructure.

70 in our directoryView all →

Education

Education technology and learning platforms built across Southern California.

9 in our directoryView all →

Real Estate & Construction

Property technology, construction tech, and real estate services.

25 in our directoryView all →