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LOS ANGELES · ORANGE COUNTY · SAN DIEGO · INLAND EMPIRE · VENTURA

Southern California's
Tech
Startup Directory

Showcasing Southern California's innovation, one startup at a time. Every funded and bootstrapped company, from seed round to first dollar of revenue, tracked as it happens.

155
companies
$5.27B
raised across all listings
31
cities

Includes SEC Form D filings from the last 3 years, plus all-time totals for companies sourced from YC and news coverage.

A futuristic humanoid robot in an indoor Tokyo setting, showcasing modern technology.

Artificial Intelligence

The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.

105 in our directoryView all →
Dramatic view of rocket boosters against a bright blue sky, showcasing aerospace technology.

Aerospace & Defense

Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.

39 in our directoryView all →
A behind-the-scenes look at a filming crew setting up a scene indoors with lighting equipment.

Entertainment & Gaming Tech

Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.

35 in our directoryView all →
Detailed view of a motherboard with visible microchips and circuits.

Semiconductor Hardware

Qualcomm and Broadcom anchor a chip-design cluster spanning the region.

7 in our directoryView all →
A healthcare worker operates a modern infusion pump in a hospital setting, ensuring precise medication delivery.

Medical Technology

A deep biotech research base and a growing bench of medical device and diagnostics startups.

291 in our directoryView all →
Laptop on office desk with a city skyline through a large window, offering a modern workspace view.

B2B

Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.

964 in our directoryView all →
Modern industrial machine in operation in a manufacturing facility showcasing advanced technology.

Industrials

Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.

97 in our directoryView all →
A woman helps a man choose a shirt in a modern clothing store.

Consumer

Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.

111 in our directoryView all →
High-tech laboratory equipment with multiple vials in a scientific research facility.

Healthcare

Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.

248 in our directoryView all →
Bitcoin coin with financial data, credit cards, and currency on a desk.

Fintech

Financial technology: payments, banking, investing, and financial infrastructure.

22 in our directoryView all →
A group of students attending a lecture wearing school uniforms, focused and attentive.

Education

Education technology and learning platforms built across Southern California.

3 in our directoryView all →
A construction worker operating a concrete mixer at an active building site, emphasizing safety gear.

Real Estate & Construction

Property technology, construction tech, and real estate services.

15 in our directoryView all →
View as table →
Series B$18.5M
Paulex Bio Inc.
La Jolla, CA · Founded 2023

Paulex Bio stands at the threshold of what could be a transformative breakthrough for type 1 and type 2 diabetes: beta cell regeneration through an oral medicine designed to eliminate the root cause of diabetes.​

Series BHealthcare
Series B$18.5M
Buffalo Market, Inc.
Los Angeles, CA · Founded 2019
Series BB2B
Series B$17.8M
Athos Therapeutics, Inc.
Torrance, CA · Founded 2019

Its co-founders include one of the founders of Kite Pharma, which was acquired by Gilead for $12 billion.

Series BHealthcare
Series B$17.8M
JINX, INC.
Los Angeles, CA · Founded 2019

Co-founded in 2019 by three former Casper executives (Terri Rockovich, Sameer Mehta, Michael Kim); its investors have included actor Will Smith.

Series BB2B
Series B$17.5M
Sift Stack, Inc.
El Segundo, CA · Founded 2022

Sift is the unified observability platform for mission-critical hardware—ingest, store, and analyze telemetry at scale across aerospace, defense, and robotics.

Series BB2B
Series B$17.1M
AristaMD, Inc.
San Diego, CA

AristaMD empowers primary care providers with excellent specialty care - improving patient outcomes with timely, cost-effective access.

Series BHealthcare
Series B$16.8M
LiveOne, Inc.
Beverly Hills, CA

LiveOne (NASDAQ:LVO) is a global digital media company dedicated to music and live entertainment. LiveOne powered by Slacker Radio is your home for music, podcasts, and more featuring Dolly Parton: DNA, Weezer: The Count Up, Album of the Week, The Magnificent Others with Billy Corgan, Hip Hop/R&B Hits

Series BB2B
Series B$16.7M
Fictions, Inc.
Los Angeles, CA · Founded 2024

Fictions is a game developer and publisher established in 2025. Current titles include LEGO Party and Beast of Reincarnation.

Series BB2B