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LOS ANGELES · ORANGE COUNTY · SAN DIEGO · INLAND EMPIRE · VENTURA

Southern California's
Tech
Startup Directory

Showcasing Southern California's innovation, one startup at a time. Every funded and bootstrapped company, from seed round to first dollar of revenue, tracked as it happens.

62
companies
$5.67B
raised across all listings
22
cities

Includes SEC Form D filings from the last 3 years, plus all-time totals for companies sourced from YC and news coverage.

A futuristic humanoid robot in an indoor Tokyo setting, showcasing modern technology.

Artificial Intelligence

The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.

105 in our directoryView all →
Dramatic view of rocket boosters against a bright blue sky, showcasing aerospace technology.

Aerospace & Defense

Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.

39 in our directoryView all →
A behind-the-scenes look at a filming crew setting up a scene indoors with lighting equipment.

Entertainment & Gaming Tech

Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.

35 in our directoryView all →
Detailed view of a motherboard with visible microchips and circuits.

Semiconductor Hardware

Qualcomm and Broadcom anchor a chip-design cluster spanning the region.

7 in our directoryView all →
A healthcare worker operates a modern infusion pump in a hospital setting, ensuring precise medication delivery.

Medical Technology

A deep biotech research base and a growing bench of medical device and diagnostics startups.

291 in our directoryView all →
Laptop on office desk with a city skyline through a large window, offering a modern workspace view.

B2B

Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.

964 in our directoryView all →
Modern industrial machine in operation in a manufacturing facility showcasing advanced technology.

Industrials

Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.

97 in our directoryView all →
A woman helps a man choose a shirt in a modern clothing store.

Consumer

Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.

111 in our directoryView all →
High-tech laboratory equipment with multiple vials in a scientific research facility.

Healthcare

Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.

248 in our directoryView all →
Bitcoin coin with financial data, credit cards, and currency on a desk.

Fintech

Financial technology: payments, banking, investing, and financial infrastructure.

22 in our directoryView all →
A group of students attending a lecture wearing school uniforms, focused and attentive.

Education

Education technology and learning platforms built across Southern California.

3 in our directoryView all →
A construction worker operating a concrete mixer at an active building site, emphasizing safety gear.

Real Estate & Construction

Property technology, construction tech, and real estate services.

15 in our directoryView all →
View as table →
Series C$218K
My Village Innovations Inc
Encinitas, CA · Founded 2024

My Village Innovations (MVI Medical) is a women-led medical device company co-founded by Andrea "Annie" Munoz, PA-C, and Alfonso Munoz, focused on reimagining the vaginal speculum for gynecologic care.

Series CHealthcare
Series C$200K
Glimmer Wish LLC
Santa Barbara, CA · Founded 2026

Glimmer Wish is Clean & Fun Beauty. Glimmer Wish was created to make self care, hair care, and beauty products that you can trust to be safe, free of harsh chemicals, and as cute as can be.

Series CB2B
Series C$167K
Renova Therapeutics, Inc.
Carlsbad, CA

Co-founder Dr. H. Kirk Hammond of UC San Diego previously co-founded Collateral Therapeutics; CEO and co-founder Jack W. Reich received an Entrepreneur of the Year award.

Series CHealthcare
Series C$150K
Inherence, Inc
Los Angeles, CA · Founded 2026

Founder Jing Jian studied math at MIT and holds an MFA in fiction from the Iowa Writers' Workshop; Inherence grew out of a novel she spent years writing.

Series CB2B
Series C$111K
AirVitalize Innovations, Inc.
Los Angeles, CA · Founded 2022

Founded by CEO Serena Allen, who built an outdoor air-purification device; Allen has since announced she is shutting the company down.

Series CIndustrials
Series C$55K
Seren Bio Corp.
Encinitas, CA · Founded 2023

Founded by Jongdae Lee, a San Diego/Encinitas-based researcher and CSO with over 20 years of experience working on inflammatory disease drug development, including viral and bacterial infections and Crohn's disease.

Series CHealthcare