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LOS ANGELES · ORANGE COUNTY · SAN DIEGO · INLAND EMPIRE · VENTURA

Southern California's
Tech
Startup Directory

Showcasing Southern California's innovation, one startup at a time. Every funded and bootstrapped company, from seed round to first dollar of revenue, tracked as it happens.

155
companies
$5.27B
raised across all listings
31
cities

Includes SEC Form D filings from the last 3 years, plus all-time totals for companies sourced from YC and news coverage.

A futuristic humanoid robot in an indoor Tokyo setting, showcasing modern technology.

Artificial Intelligence

The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.

105 in our directoryView all →
Dramatic view of rocket boosters against a bright blue sky, showcasing aerospace technology.

Aerospace & Defense

Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.

39 in our directoryView all →
A behind-the-scenes look at a filming crew setting up a scene indoors with lighting equipment.

Entertainment & Gaming Tech

Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.

35 in our directoryView all →
Detailed view of a motherboard with visible microchips and circuits.

Semiconductor Hardware

Qualcomm and Broadcom anchor a chip-design cluster spanning the region.

7 in our directoryView all →
A healthcare worker operates a modern infusion pump in a hospital setting, ensuring precise medication delivery.

Medical Technology

A deep biotech research base and a growing bench of medical device and diagnostics startups.

291 in our directoryView all →
Laptop on office desk with a city skyline through a large window, offering a modern workspace view.

B2B

Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.

964 in our directoryView all →
Modern industrial machine in operation in a manufacturing facility showcasing advanced technology.

Industrials

Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.

97 in our directoryView all →
A woman helps a man choose a shirt in a modern clothing store.

Consumer

Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.

111 in our directoryView all →
High-tech laboratory equipment with multiple vials in a scientific research facility.

Healthcare

Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.

248 in our directoryView all →
Bitcoin coin with financial data, credit cards, and currency on a desk.

Fintech

Financial technology: payments, banking, investing, and financial infrastructure.

22 in our directoryView all →
A group of students attending a lecture wearing school uniforms, focused and attentive.

Education

Education technology and learning platforms built across Southern California.

3 in our directoryView all →
A construction worker operating a concrete mixer at an active building site, emphasizing safety gear.

Real Estate & Construction

Property technology, construction tech, and real estate services.

15 in our directoryView all →
View as table →
Series B$24.1M
ASHOC Beverage, LLC
Newport Beach, CA · Founded 2018

A SHOC Energy was founded in 2019 by Lance Collins, who previously founded the beverage brands Fuze, NOS Energy, and Core.

Series BConsumer
Series B$24.0M
Kinderfarms LLC
Redondo Beach, CA · Founded 2022

KinderFarms was co-founded in 2018 by actress Jessica Biel, along with Jeremy Adams and Greg Willsey.

Series BIndustrials
Series B$23.0M
Abrexa Pharmaceuticals, Inc.
San Diego, CA
Series BHealthcare
Series B$22.0M
AgentAI Holdings, Inc.
Woodland Hills, CA · Founded 2025

Medical billing and revenue cycle management where AI agents carry every claim and expert billers fight the hard dollars. Free scan of your last 90 days.

Series BB2B
Series B$21.0M
Kinetic Automation Inc.
Santa Ana, CA · Founded 2021

CEO Nikhil Naikal is a two-time founder in the automotive industry — he previously founded Mapper, which was acquired by Velodyne Lidar; Kinetic has raised $31M from Menlo Ventures, Lux Capital and Construct Capital.

Series BB2B
Series B$21.0M
SYDNEXIS, INC.
Del Mar, CA

Raised a $45M Series B from RA Capital, Longitude Capital, Visionary Ventures and Bluestem Capital to develop a drug for pediatric myopia progression.

Series BB2B
Series B$20.6M
Pictor Labs, Inc.
Los Angeles, CA · Founded 2019

Pictor Labs is The Virtual Staining Company enabling digital pathology adoption through computational virtual staining technology that preserves tissue for comprehensive downstream analysis.

Series BHealthcare
Series B$20.3M
Sylke, Inc.
La Jolla, CA · Founded 2023

SYLKE® Skin Closure is a sterile, single-use, silk fibroin mesh strip with a pressure-sensitive adhesive intended for topical skin closure and wound support. The device is used to hold together well-approximated skin edges of a wound, and to cover and protect the wound. Learn more at sylke.com.

Series BHealthcare