Southern California's
Tech
Startup Directory
Showcasing Southern California's innovation, one startup at a time. Every funded and bootstrapped company, from seed round to first dollar of revenue, tracked as it happens.
Includes SEC Form D filings from the last 3 years, plus all-time totals for companies sourced from YC and news coverage.
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
A Santa Monica company still operating in stealth mode (its actual business is undisclosed) that has nonetheless filed SEC Form D notices for roughly $150M in offerings since 2023.
According to Crunchbase, it was founded by actor Darius McCrary, best known for playing Eddie Winslow on the sitcom "Family Matters."
$106.8MRenovaro revolutionizes cancer and neurology care through early detection, drug discovery, and personalized treatments. AI-powered precision medicine.
A Foresite Labs-incubated biotech backed by Foresite Capital, Qiming Venture Partners, and Samsara BioCapital that raised over $100M before being folded into Candid Therapeutics' $370M launch in 2024.
Series C$103.0MCarlsmed® uses patient data and digital technologies to create optimal surgical plans and personalized aprevo® spine fusion devices.
Series C$102.0MMach Industries is building faster, smarter defense infrastructure for the modern era.
Series B$100.8MAutobahn aims to improve life health for people affected by CNS disorders by driving the regenerative power of the human body.
Series C$100.4MJenaValve's investors include Bain Capital Life Sciences and the Qatar Investment Authority.