Southern California's
Tech
Startup Directory
Showcasing Southern California's innovation, one startup at a time. Every funded and bootstrapped company, from seed round to first dollar of revenue, tracked as it happens.
Includes SEC Form D filings from the last 3 years, plus all-time totals for companies sourced from YC and news coverage.
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
Series A$25.0MProper Voltage is the digital bridge that seamlessly links power and product, opening up access to more choices and possibilities.
Poseida Therapeutics, a San Diego cell and gene therapy company founded by Eric Ostertag and once listed on Nasdaq as PSTX, was acquired by Roche in a December 2024 tender offer at $9.00/share cash plus a contingent value right.
Series A$23.5MAccess to Social Security 3-5 days early.
Series A$23.2MQuintessent is developing optical connectivity solutions to scale computing and Artificial Intelligence (A.I.).
Series A$22.6MThe 1st warehouse-native platform for experimentation, feature flags, and product analytics. Open source and fully transparent. Trusted by 3,000+ companies.
Series A$22.4MWelcome to VIAVIA! Redefining the fashion experience for a new generation // Enjoy free shipping and returns on all orders // New Designers and products dropping daily
Serimmune was founded by Patrick Daugherty, a former UC Santa Barbara chemical engineering professor who also co-founded CytomX Therapeutics; backers include Illumina Ventures, LabCorp, and Merck.
Series A$22.0MFounded in 2019 by Marc Washington, who previously grew Beachbody into a $1 billion+ company; the LA-based startup (maker of Muniq gut-health shakes) raised an $8.2M Series A backed by venture foundry The Production Board.