Southern California's
Tech
Startup Directory
Showcasing Southern California's innovation, one startup at a time. Every funded and bootstrapped company, from seed round to first dollar of revenue, tracked as it happens.
Includes SEC Form D filings from the last 3 years, plus all-time totals for companies sourced from YC and news coverage.
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
Series A$4.8MCo-owned by Issa Rae & Hannah Diop, Sienna Naturals is a vegan hair care line that delivers results. The line is specifically formulated to hydrate textured hair, revive your curl pattern, and repair styling damage.
Series A$4.7MTransposon Therapeutics, Inc. is developing TPN-101 (also known as Censavudine) and other LINE-1 reverse transcriptase inhibitors for the treatment of rare neurodegenerative diseases such as progressive supranuclear palsy (PSP), amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD).
Series A$4.6MModern and intuitive avionics. Our hardware and software are designed from the ground up using state-of-the-art UI/UX technology to create beautiful and safe avionics.
Series A$4.5MDiscover Balboa Geolocation's cutting-edge geolocation solutions for defense and commercial markets, ensuring accuracy in challenging environments.
Nasdaq-listed (QLGN); received a $41 million strategic PIPE investment from Faraday Future, whose founder is Chinese entrepreneur YT Jia (Jia Yueting).
Founded in 2018 by Ahmad Malkawi, a wireless-industry veteran with prior stints at AT&T, Qualcomm, and Sprint; the Irvine-based company builds telecom hardware, software, and AI solutions for IoT connectivity.
Series A$4.2MAI-driven medical coding from Synaptec Health - a more accurate, secure, and comprehensive solution for all your medical coding needs.
Series A$4.2MTenovi remote patient monitoring 40+ FDA-cleared hardware devices power RPM and RTM programs with the first plug-and-play Cellular Gateway.