Southern California's
Tech
Startup Directory
Showcasing Southern California's innovation, one startup at a time. Every funded and bootstrapped company, from seed round to first dollar of revenue, tracked as it happens.
Includes SEC Form D filings from the last 3 years, plus all-time totals for companies sourced from YC and news coverage.
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
Series A$10.9MWe're an ambitious startup developing a groundbreaking new UGC gaming platform.
Series A$10.8MFounded by Atandra Burman, the Carlsbad, California company is developing a transdermal wearable for early detection of heart attacks.
Series A$10.8MTransform your productivity, efficiency & scalability through the MES manufacturing software from First Resonance!
Series A$10.7MPublicly traded on Nasdaq (BRFH), the company was founded by Riccardo Delle Coste, who invented its patented blended-beverage technology in 2005.
Series A$10.7MIdentify complex security vulnerabilities and sensitive data exposures to reduce risk of security incidents and provide assurance to your customers.
Series A$10.6MDirect Investment & Distribution Platform Gulf of America
Series A$10.6MCooler Heads is the creator of Amma™, an FDA-cleared scalp cooling system that helps cancer patients reduce hair loss during chemotherapy. Amma delivers hospital-grade cold-cap therapy that’s simple, portable, and patient-first.
Digital Surgery Systems, Inc. is the legal name behind True Digital Surgery, a Goleta, CA maker of 3D robotic-assisted surgical microscopy systems that was fully acquired by German medical device company B. Braun SE in September 2025.